Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Sheng-Ning Yuan"'
Cbl Negatively Regulates NLRP3 Inflammasome Activation through GLUT1-Dependent Glycolysis Inhibition
Autor:
Hsin-Chung Lin, Yu-Jen Chen, Yau-Huei Wei, Yu-Ting Chuang, Su-Heng Hsieh, Jing-Yu Hsieh, Yi-Lin Hsieh, David M. Ojcius, Kuo-Yang Huang, I.-Che Chung, Sheng-Ning Yuan, Yu-Sun Chang, Lih-Chyang Chen
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 14, p 5104 (2020)
Activation of the nod-like receptor 3 (NLRP3) inflammasomes is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Cbl plays a pivotal role in suppressing NLRP3 inflammasome acti
Externí odkaz:
https://doaj.org/article/32a319ce91a54b7caaec0925ec873ee4
Autor:
I-Che Chung, Chun-Nan OuYang, Sheng-Ning Yuan, Hsin-Chung Lin, Kuo-Yang Huang, Pao-Shu Wu, Chia-Yuan Liu, Kuen-Jou Tsai, Lai-Keng Loi, Yu-Jen Chen, An-Ko Chung, David M. Ojcius, Yu-Sun Chang, Lih-Chyang Chen
Publikováno v:
Nutrients, Vol 11, Iss 3, p 516 (2019)
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Inflammation contributes to cancer development and inflammatory bowel disease is an important risk factor for CRC. The aim of this study is to assess whether a widely used prob
Externí odkaz:
https://doaj.org/article/ac73e4b917b54fc9bc33e4a5fa898835
Autor:
Ching-Liang Chu, David M. Ojcius, Yu-Jen Chen, Chun-Nan OuYang, Kuo-Yang Huang, An-Ko Chung, Lih-Chyang Chen, Yu-Sun Chang, I-Che Chung, Sheng-Ning Yuan, Hsin-Chung Lin
Publikováno v:
Cell Death and Disease, Vol 9, Iss 11, Pp 1-14 (2018)
Cell Death & Disease
Cell death & disease, vol 9, iss 11
Cell Death & Disease
Cell death & disease, vol 9, iss 11
Activation of the NLRP3 inflammasome is crucial for immune defense, but improper and excessive activation causes inflammatory diseases. We previously reported that Pyk2 is essential for NLRP3 inflammasome activation. Here we show that the Src-family
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6428b0bdeecee6b311c115f92ee0657
http://link.springer.com/article/10.1038/s41419-018-1163-z
http://link.springer.com/article/10.1038/s41419-018-1163-z
Autor:
Wen-Yu Chuang, I-Che Chung, Yu-Sun Chang, Chun-Nan OuYang, Lih-Chyang Chen, Chih-Ching Wu, David M. Ojcius, Ngan-Ming Tsang, Tzu-Chieh Liao, Sheng-Ning Yuan
Publikováno v:
Mol Cell Proteomics
We previously reported that tumor inflammasomes play a key role in tumor control and act as favorable prognostic markers in nasopharyngeal carcinoma (NPC). Activated inflammasomes frequently form distinguishable specks and govern the cellular secreti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a9004f33ec2d426bc8fb7a35dcce0cf
https://pubmed.ncbi.nlm.nih.gov/31723016
https://pubmed.ncbi.nlm.nih.gov/31723016
Autor:
Wei-Ning Lin, Sheng-I Hu, Lih-Chyang Chen, Hsin-Chung Lin, Yu-Ting Chuang, Kuo-Yang Huang, Sheng-Ning Yuan, David M. Ojcius, Chun-Nan OuYang, I-Che Chung, Yu-Sun Chang, Yu-Jen Chen
Publikováno v:
Cytokine. 127
Psoriasis is a chronic inflammatory skin disease that affects about 2% of the general population. Activation of the Absent in Melanoma 2 (AIM2) inflammasome is crucial for immune defense, but it can also cause inflammatory and autoimmune diseases, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::618f55fb951f60ebd82398c696cc8940
https://pubmed.ncbi.nlm.nih.gov/31837587
https://pubmed.ncbi.nlm.nih.gov/31837587
Autor:
An-Ko Chung, Lih-Chyang Chen, Lai-Keng Loi, Kuo-Yang Huang, Pao-Shu Wu, I-Che Chung, Yu-Jen Chen, Chun-Nan OuYang, Sheng-Ning Yuan, Kuen-Jou Tsai, Hsin-Chung Lin, Yu-Sun Chang, David M. Ojcius, Chia-Yuan Liu
Publikováno v:
Nutrients, vol 11, iss 3
Nutrients, Vol 11, Iss 3, p 516 (2019)
Nutrients
Volume 11
Issue 3
Nutrients, Vol 11, Iss 3, p 516 (2019)
Nutrients
Volume 11
Issue 3
Colorectal cancer (CRC) is one of the most common malignancies worldwide. Inflammation contributes to cancer development and inflammatory bowel disease is an important risk factor for CRC. The aim of this study is to assess whether a widely used prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41367669261751ceba3462170c55b3f1
https://escholarship.org/uc/item/4sq1g22v
https://escholarship.org/uc/item/4sq1g22v
Autor:
Hsin-Pai Li, Yu-Sun Chang, Chun-Nan OuYang, Ching-Liang Chu, Jau-Song Yu, Yu-Jen Chen, David M. Ojcius, Hui-Ru Shieh, I-Che Chung, Lih-Chyang Chen, Jeng-Ting Chen, Sheng-Ning Yuan
Publikováno v:
Scientific Reports
Scientific reports, vol 6, iss 1
Scientific reports, vol 6, iss 1
The inflammasome adaptor protein, ASC, contributes to both innate immune responses and inflammatory diseases via self-oligomerization, which leads to the activation of the protease, caspase-1. Here, we report that the cytosolic tyrosine kinases, FAK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8701a3edb62891a94294407f41b8e984
http://europepmc.org/articles/PMC5087076
http://europepmc.org/articles/PMC5087076
Autor:
Sheng Ning Yuan, 袁聖甯
96
Nasopharyngeal carcinoma (NPC), which is prominent in Southern Asia including Taiwan, is closely associated with genetic background and Epstein-Barr virus (EBV) infection. Monocyte chemoattractant protein-1 (MCP-1) is known as a potent chemoa
Nasopharyngeal carcinoma (NPC), which is prominent in Southern Asia including Taiwan, is closely associated with genetic background and Epstein-Barr virus (EBV) infection. Monocyte chemoattractant protein-1 (MCP-1) is known as a potent chemoa
Externí odkaz:
http://ndltd.ncl.edu.tw/handle/74436258246565136669