Zobrazeno 1 - 10
of 464
pro vyhledávání: '"Sheng-Nan Wu"'
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 10, Pp 442-453 (2024)
Abstract Despite advancement in anti‐seizure medications, 30% of patients continue to experience recurrent seizures. Previous data indicated the antiepileptic properties of melatonin and its agonists in several animal models. However, the underlyin
Externí odkaz:
https://doaj.org/article/0e6496c17f0d47ef958f5c5c0e933a89
Autor:
Geng-Bai Lin, Chia-Lung Shih, Rasa Liutkevičienė, Vita Rovite, Edmund Cheung So, Chao-Liang Wu, Sheng-Nan Wu
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 128-141 (2024)
As the need for effective antiviral treatment intensifies, such as with the coronavirus disease 19 (COVID-19) infection, it is crucial to understand that while the mechanisms of action of these drugs or compounds seem apparent, they might also intera
Externí odkaz:
https://doaj.org/article/b5f0b6da8f1349f480475baa21045259
Autor:
Greta Gedvilaite-Vaicechauskiene, Loresa Kriauciuniene, Arimantas Tamasauskas, Vita Rovite, Ilona Mandrika, Sheng-Nan Wu, Chin-Wei Huang, Lina Poskiene, Rasa Liutkeviciene
Publikováno v:
Medicina, Vol 60, Iss 8, p 1252 (2024)
Background and Objectives: This study explores the complex pathogenesis of pituitary adenomas (PAs), prevalent intracranial tumors in the pituitary gland. Despite their generally benign nature, PAs exhibit a diverse clinical spectrum involving hormon
Externí odkaz:
https://doaj.org/article/94cac27050e744549fdb60a5a7012498
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/d3c1c64457e54b8a9f54981c4ddca37d
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
Carisbamate (CRS, RWJ-333369) is a new anti-seizure medication. It remains unclear whether and how CRS can perturb the magnitude and/or gating kinetics of membrane ionic currents, despite a few reports demonstrating its ability to suppress voltage-ga
Externí odkaz:
https://doaj.org/article/ccfd70f2ef644a98b7d1110a489e245e
Publikováno v:
Biomedicines, Vol 11, Iss 10, p 2651 (2023)
Cannabidiol (CBD) is a naturally occurring compound found in the Cannabis plant that is known for its potential therapeutic effects. However, its impact on membrane ionic currents remains a topic of debate. This study aimed to investigate how CBD mod
Externí odkaz:
https://doaj.org/article/694d440352744b70a75c91ae1b05bd5b
Publikováno v:
Biomedicines, Vol 11, Iss 8, p 2177 (2023)
The hyperpolarization-activated cation current (Ih) exhibits a slowly activating time course of the current (Ih) when the cell membrane is hyperpolarized for an extended duration. It is involved in generating electrical activity in various excitable
Externí odkaz:
https://doaj.org/article/56dcc7692b474f51b75a2ecd06c5bcf2
Autor:
Hong-Fu Li, Yu-Lan Chen, Ling Zhuang, Dian-Fu Chen, Hua-Zhen Ke, Wen-Jiao Luo, Gong-Lu Liu, Sheng-Nan Wu, Wen-Hao Zhou, Zhi-Qi Xiong, Zhi-Ying Wu
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-4 (2021)
Externí odkaz:
https://doaj.org/article/2ca3f68050574d9285259ab5681da437
Publikováno v:
Biomedicines, Vol 11, Iss 5, p 1351 (2023)
Omecamtiv mecarbil (OM, CK-1827452) is recognized as an activator of myosin and has been demonstrated to be beneficial for the treatment of systolic heart failure. However, the mechanisms by which this compound interacts with ionic currents in electr
Externí odkaz:
https://doaj.org/article/12d591edbb3144fc91d72578cab61049
Publikováno v:
BMC Pharmacology and Toxicology, Vol 22, Iss 1, Pp 1-9 (2021)
Abstract Background Vigabatrin (VGB) is an approved non-traditional antiepileptic drug that has been revealed to have potential for treating brain tumors; however, its effect on ionic channels in glioma cells remains largely unclear. Methods With the
Externí odkaz:
https://doaj.org/article/3b1f39587359415e977b75b614c2ed9d