Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Sheng-Ming Peng"'
Publikováno v:
Chinese Chemical Letters. 30:1224-1228
Recently we found that multi-walled carbon nanotube (MWCNT) exposure alters the mRNA levels of endoplasmic reticulum (ER) stress/autophagic genes, but the impact of biological molecules on this response is unclear. Herein, we compared the different a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80ed1ee16c2f528f7b634be524638df5
https://doi.org/10.1016/j.cclet.2019.03.042
https://doi.org/10.1016/j.cclet.2019.03.042
Publikováno v:
Chinese Chemical Letters. 25:1094-1098
Several derivatives have been synthesized from chrysin, diosmetin, apigenin, and luteolin, which were isolated from diverse natural plants. The α-glucosidase inhibitory activity of these compounds was evaluated. The glucosidase inhibitory activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e7963305e0cabb01c907e8d05746233
https://doi.org/10.1016/j.cclet.2014.05.021
https://doi.org/10.1016/j.cclet.2014.05.021
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:4301-4310
Aldose reductase (AR) plays an important role in the design of drugs that prevent and treat diabetic complications. Aldose reductase inhibitors (ARIs) have received significant attentions as potent therapeutic drugs. Based on combination principles,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f526e3dc460169a6edc402bd6d92cda
https://doi.org/10.1016/j.bmc.2013.04.066
https://doi.org/10.1016/j.bmc.2013.04.066
Nitric Oxide-Donating Derivatives of Chrysin Stimulate Angiogenesis and Upregulating VEGF Production
Publikováno v:
Advanced Materials Research. 340:363-368
Angiogenesis, the development of new capillaries from pre-existing vessels, requires the coordinate activation of endothelial cells, which migrate and proliferate to form functional vessels. Endothelial dysfunction and decreased nitric oxide bioavail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac12574320f7b0c0560a6f4ae15bdbf5
https://doi.org/10.4028/www.scientific.net/amr.340.363
https://doi.org/10.4028/www.scientific.net/amr.340.363
Autor:
Yuan-Jian Li, Han-Wu Deng, Li-Feng Tan, Qiong Yuan, Sheng-Ming Peng, Xiao-Qing Zou, Chang-Ping Hu
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:3020-3025
Vascular complications are major causes of disability and death in patients with diabetes mellitus. It is often characterized by endothelial dysfunction. Studies have shown that either the loss of nitric oxide bioactivity or the decreased biosynthesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d64e60335defa38500968261b3a79e9
https://doi.org/10.1016/j.bmc.2010.03.056
https://doi.org/10.1016/j.bmc.2010.03.056
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:1264-1266
Two types of new chrysin derivatives were prepared by coupling NO donors of alkyl nitrate and furazan derivatives and were fully characterized by 1 H NMR and other techniques. These compounds were tested in human umbilical vein endothelial cells (HUV
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cde855189f9644a09bda87504d2d33
https://doi.org/10.1016/j.bmcl.2008.12.116
https://doi.org/10.1016/j.bmcl.2008.12.116
Publikováno v:
Bioorganicmedicinal chemistry. 22(5)
α-Glucosidase (AG) play crucial roles in the digestion of carbohydrates. Inhibitors of α-glucosidase (AGIs) are promising candidates for the development of anti-diabetic drugs. Here, five series of apigenin and chrysin nitric oxide (NO)-donating de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6296a6ac2e8ee6a849a1086b123ecba
https://pubmed.ncbi.nlm.nih.gov/24508143
https://pubmed.ncbi.nlm.nih.gov/24508143
Publikováno v:
Journal of agricultural and food chemistry. 60(40)
The water extraction and composition of pu-erh tea, as well as the hypoglycemic effect of the water extract of pu-erh tea (WEPT) in vivo and in vitro, are reported to investigate its hypoglycemic effect on diabetes. High-performance liquid chromatogr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c341a27bd80be1be47ef8501729fe333
https://pubmed.ncbi.nlm.nih.gov/22957968
https://pubmed.ncbi.nlm.nih.gov/22957968
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(4)
A series of furoxan-based nitric oxide-releasing chrysin derivatives were synthesized. Pharmacological assays indicated that all chrysin derivatives exhibited in vitro inhibitory activities against aldose reductase and advanced glycation end-product
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2707ca373e56d1d4d3e3092a14d641eb
https://pubmed.ncbi.nlm.nih.gov/21256748
https://pubmed.ncbi.nlm.nih.gov/21256748
Publikováno v:
Journal of Agricultural & Food Chemistry; 10/10/2012, Vol. 60 Issue 40, p10126-10132, 7p