Výsledky vyhledávání - "Sheng-Lan Shi"

Cooperative methylation of human tRNA3Lys at positions A58 and U54 drives the early and late steps of HIV-1 replication

Autor: Sheng-Lan Shi, Hiroyuki Fukuda, Mayumi Hirayama, Kazuhito Tomizawa, Hiroyuki Oshiumi, Fan-Yan Wei, Takahiro Yamamoto, Takeshi Chujo, Taku Kaitsuka

Publikováno v: Nucleic Acids Research

Retroviral infection requires reverse transcription, and the reverse transcriptase (RT) uses cellular tRNA as its primer. In humans, the TRMT6-TRMT61A methyltransferase complex incorporates N1-methyladenosine modification at tRNA position 58 (m1A58);

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52054e2351b7e972f44783004b184e50
https://doi.org/10.1093/nar/gkab879

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Export of RNA-derived modified nucleosides by equilibrative nucleoside transporters defines the magnitude of autophagy response and Zika virus replication

Autor: Kazuhito Tomizawa, Sheng-Lan Shi, Hiroyuki Oshiumi, Hiroyuki Fukuda, Fan-Yan Wei, Takahisa Kouwaki, Takeshi Chujo

Publikováno v: RNA Biology
article-version (VoR) Version of Record

RNA contains a wide variety of posttranscriptional modifications covalently attached to its base or sugar group. These modified nucleosides are liberated from RNA molecules as the consequence of RNA catabolism and released into extracellular space, b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f046c5111671356dea5b6f3b798b7aaa

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Amyloid β-42 induces neuronal apoptosis by targeting mitochondria

Autor: Ye‑Ru Li, Yang‑Yang Hu, Xiao‑Jian Han, Li‑Ping Jiang, Sheng‑Lan Shi, Yu‑Ying Wan, Hong‑Li Wu, Zhang‑Jian Yang, Miao‑Yu Guo

Publikováno v: Molecular Medicine Reports

Alzheimer's disease (AD), with a typical pathological hallmark of amyloid‑beta (Aβ)‑containing plaques and neurofibrillary tangles, is one of the most common types of chronic neurodegenerative diseases. Aβ oligomers serve a crucial role in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4d0ed5f7b2c6899b3da8d123b1da937
https://doi.org/10.3892/mmr.2017.7203

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Involvement of mitochondrial dynamics in the antineoplastic activity of cisplatin in murine leukemia L1210 cells

Autor: Hong‑Li Wu, Miao-Yu Guo, Xiao-Jian Han, Sheng-Lan Shi, Yu-Ying Wan, Li-Ping Jiang, Yong-Fang Wei

Publikováno v: Oncology Reports. 38:985-992

Leukemia is a type of hematopoietic stem cell malignant cloned disease with high mortality. Cisplatin-based chemotherapy is one of the most common treatments for leukemia. Similar to other chemotherapeutic agents, cisplatin resistance has become a se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79acfab8114b8c0b12153e43ba826f8e
https://doi.org/10.3892/or.2017.5765

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