Zobrazeno 1 - 10
of 115
pro vyhledávání: '"Sheng Zhong Duan"'
Autor:
Peter E O'Donnell, Xiu Zhen Ye, Melissa A DeChellis, Vannessa M Davis, Sheng Zhong Duan, Richard M Mortensen, David S Milstone
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0160636 (2016)
Peroxisome proliferator activated receptor gamma (PPARγ) is a pleiotropic ligand activated transcription factor that acts in several tissues to regulate adipocyte differentiation, lipid metabolism, insulin sensitivity and glucose homeostasis. PPARγ
Externí odkaz:
https://doaj.org/article/fe1360a1884649e6b99b5b554bfbab27
Autor:
Chao Li, Yu Yao Zhang, Ryan A Frieler, Xiao Jun Zheng, Wu Chang Zhang, Xue Nan Sun, Qing Zhen Yang, Shu Min Ma, Baozhuan Huang, Stefan Berger, Wang Wang, Yong Wu, Ying Yu, Sheng Zhong Duan, Richard M Mortensen
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110950 (2014)
Mineralocorticoid receptor (MR) blockade has been shown to suppress cardiac hypertrophy and remodeling in animal models of pressure overload (POL). This study aims to determine whether MR deficiency in myeloid cells modulates aortic constriction-indu
Externí odkaz:
https://doaj.org/article/b31ec9161d554da1aa47956b8cbccd75
Publikováno v:
Cell Death Discovery, Vol 9, Iss 1, Pp 1-9 (2023)
Abstract Macrophage polarization plays an important role in asthma. Nuclear receptor corepressor 1 (NCOR1) plays an important role in metabolic and cardiovascular diseases by regulating the function of macrophages. The aim of this research was to exa
Externí odkaz:
https://doaj.org/article/4c0f75dc41f04b06b4ec469fc3dfe244
Autor:
Xue-Bing Bai, Shuo Xu, Lu-Jun Zhou, Xiao-Qian Meng, Yu-Lin Li, Yan-Lin Chen, Yi-Han Jiang, Wen-Zhen Lin, Bo-Yan Chen, Lin-Juan Du, Guo-Cai Tian, Yan Liu, Sheng-Zhong Duan, Ya-Qin Zhu
Publikováno v:
Microbiome, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background Parkinson’s disease (PD) is a common chronic neurological disorder with a high risk of disability and no cure. Periodontitis is an infectious bacterial disease occurring in periodontal supporting tissues. Studies have shown that
Externí odkaz:
https://doaj.org/article/375dd234b9a448a695dd6555d7af6809
Autor:
Michelangela Barbieri, Clara Di Filippo, Antonietta Esposito, Raffaele Marfella, Maria Rosaria Rizzo, Michele D'Amico, Franca Ferraraccio, Cristina Di Ronza, Sheng Zhong Duan, Richard M Mortensen, Francesco Rossi, Giuseppe Paolisso
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e35999 (2012)
Understanding the molecular regulatory mechanisms controlling for myocardial lipid metabolism is of critical importance for the development of new therapeutic strategies for heart diseases. The role of PPARγ and thiazolidinediones in regulation of m
Externí odkaz:
https://doaj.org/article/6196ef34124949568f4f242482bdbd90
Publikováno v:
PPAR Research, Vol 2008 (2008)
Peroxisome proliferator-activated receptor-γ (PPAR-γ), an essential transcriptional mediator of adipogenesis, lipid metabolism, insulin sensitivity, and glucose homeostasis, is increasingly recognized as a key player in inflammatory cells and in ca
Externí odkaz:
https://doaj.org/article/1d17facecbf545f5b1612992b11c4aa3
Autor:
Hui-Lin Ye, Meng-Fan Zhi, Bo-Yan Chen, Wen-Zhen Lin, Yu-Lin Li, Shi-Jia Huang, Lu-Jun Zhou, Shuo Xu, Jun Zhang, Wu-Chang Zhang, Qiang Feng, Sheng-Zhong Duan
Publikováno v:
mSystems, Vol 9, Iss 1 (2024)
ABSTRACTThe microbiota plays an important role in both hypertension (HTN) and periodontitis (PD), and PD exacerbates the development of HTN by oral and gut microbiota. Previous studies have focused on exploring the importance of the bacteriome in HTN
Externí odkaz:
https://doaj.org/article/9025433a1d7d492991416a901e1a2e4c
Autor:
Wen-Zhen Lin, Bo-Yan Chen, Peng Qiu, Lu-Jun Zhou, Yu-Lin Li, Lin-Juan Du, Yuan Liu, Yong-Li Wang, Hong Zhu, Xiao-Yu Wu, Xiaobing Liu, Sheng-Zhong Duan, Ya-Qin Zhu
Publikováno v:
Heliyon, Vol 9, Iss 12, Pp e23040- (2023)
Evidence suggests that the DNA of oral pathogens is detectable in the dilated aortic tissue of abdominal aortic aneurysm (AAA), one of the most fatal cardiovascular diseases. However, the association between oral microbial homeostasis and aneurysm fo
Externí odkaz:
https://doaj.org/article/7f671c2de62446b6bdaf698c40d77e4c
Autor:
Hong Zhu, Min He, Yong‐Li Wang, Yuanxin Zhang, Jingsong Dong, Bo‐Yan Chen, Yu‐Lin Li, Lu‐Jun Zhou, Lin‐Juan Du, Yuan Liu, Wu‐Chang Zhang, Dean Ta, Sheng‐Zhong Duan
Publikováno v:
Bioengineering & Translational Medicine, Vol 8, Iss 6, Pp n/a-n/a (2023)
Abstract Doxorubicin (DOX)‐induced cardiotoxicity limits its broad use as a chemotherapy agent. The development of effective and non‐invasive strategies to prevent DOX‐associated adverse cardiac events is urgently needed. We aimed to examine wh
Externí odkaz:
https://doaj.org/article/d6d93053e94042b4aa78e81b36c4cd6b
Autor:
Chu-Mao Chen, Xiao-Qian Meng, Hong Zhu, Ting Liu, Yuan Liu, Lu-Jun Zhou, Guo-Dong Zhu, Xiao-Bei Chen, Xu-Guang Guo, Sheng-Zhong Duan
Publikováno v:
Journal of Lipid Research, Vol 64, Iss 11, Pp 100449- (2023)
Activation of brown adipose tissue (BAT) contributes to energy dissipation and metabolic health. Although mineralocorticoid receptor (MR) antagonists have been demonstrated to improve metabolism under obesity, the underlying mechanisms remain incompl
Externí odkaz:
https://doaj.org/article/dcdf5baebb5b49c0bb8b265bbb89f6e4