Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Sheng Yu Ku"'
Autor:
Sylvan C. Baca, David Y. Takeda, Ji-Heui Seo, Justin Hwang, Sheng Yu Ku, Rand Arafeh, Taylor Arnoff, Supreet Agarwal, Connor Bell, Edward O’Connor, Xintao Qiu, Sarah Abou Alaiwi, Rosario I. Corona, Marcos A. S. Fonseca, Claudia Giambartolomei, Paloma Cejas, Klothilda Lim, Monica He, Anjali Sheahan, Amin Nassar, Jacob E. Berchuck, Lisha Brown, Holly M. Nguyen, Ilsa M. Coleman, Arja Kaipainen, Navonil De Sarkar, Peter S. Nelson, Colm Morrissey, Keegan Korthauer, Mark M. Pomerantz, Leigh Ellis, Bogdan Pasaniuc, Kate Lawrenson, Kathleen Kelly, Amina Zoubeidi, William C. Hahn, Himisha Beltran, Henry W. Long, Myles Brown, Eva Corey, Matthew L. Freedman
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
The molecular processes that lead to neuroendocrine prostate cancer after treating prostate adenocarcinoma (PRAD) are not well understood. Here the authors show that regulation by FOXA1 and changes in the epigenomic profile drive the transition from
Externí odkaz:
https://doaj.org/article/c9b61c7dcf794ef5947cc08ad8806fa3
Autor:
Varadha Balaji Venkadakrishnan, Adam G. Presser, Richa Singh, Matthew A. Booker, Nicole A. Traphagen, Kenny Weng, Nathaniel C. E. Voss, Navin R. Mahadevan, Kei Mizuno, Loredana Puca, Osasenaga Idahor, Sheng-Yu Ku, Martin K. Bakht, Ashir A. Borah, Zachary T. Herbert, Michael Y. Tolstorukov, David A. Barbie, David S. Rickman, Myles Brown, Himisha Beltran
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Enhancer of zeste homolog 2 (EZH2) is a histone methyltransferase and emerging therapeutic target that is overexpressed in most castration-resistant prostate cancers and implicated as a driver of disease progression and resistance to hormona
Externí odkaz:
https://doaj.org/article/3a09fcc40a5640f5a97df040787fb9ed
Autor:
Sheng-Yu Ku1, Yanqing Wang2, Garcia, Maria Mica1, Yasutaka Yamada1, Kei Mizuno1, Long, Mark D.3, Rosario, Spencer2,3, Chinnam, Meenalakshmi2, Al Assaad, Majd4, Puca, Loredana5, Min Jin Kim1, Bakht, Martin K.1, Venkadakrishnan, Varadha Balaji1, Robinson, Brian D.4, Acosta, Andrés M.6, Wadosky, Kristine M.2, Mosquera, Juan Miguel4, Goodrich, David W.2,7 david.goodrich@roswellpark.org, Beltran, Himisha1 himisha_beltran@dfci.harvard.edu.
Publikováno v:
Journal of Clinical Investigation. 9/3/2024, Vol. 134 Issue 17, p1-17. 17p.
Autor:
Martin K. Bakht, Yasutaka Yamada, Sheng-Yu Ku, Varadha Balaji Venkadakrishnan, Joshua A. Korsen, Teja M. Kalidindi, Kei Mizuno, Shin Hye Ahn, Ji-Heui Seo, Maria Mica Garcia, Francesca Khani, Olivier Elemento, Henry W. Long, Alain Chaglassian, Nagavarakishore Pillarsetty, Jason S. Lewis, Matthew Freedman, Anthony P. Belanger, Quang-De Nguyen, Himisha Beltran
Publikováno v:
Nature Cancer. 4:699-715
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8055913d919d251e89a3a93d03518d65
https://doi.org/10.1038/s43018-023-00539-6
https://doi.org/10.1038/s43018-023-00539-6
Autor:
Roberto Pili, Georg A. Bjarnason, Sreenivasulu Chintala, Michael Buck, Gerald Fetterly, Joshua Prey, Ashley Orillion, Sheng-Yu Ku, Swathi Ramakrishnan, Li Shen, Dylan Conroy, Maria Tsompana, Jonathan Bard, Paula Sotomayor, Kiersten Marie Miles, Eric Ciamporcero, Remi Adelaiye
Supplementary Fig. 5. Histone marks expression associated with resistance to sunitinib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::780089b8d33dd75288e9e1e7c3f5f271
https://doi.org/10.1158/1535-7163.22501774
https://doi.org/10.1158/1535-7163.22501774
Autor:
Roberto Pili, Angela Coxon, Sean Caenepeel, Karen Rex, Sheng-yu Ku, Swathi Ramakrishnan, Eric Ciamporcero, Sreenivasulu Chintala, Kiersten Marie Miles, Li Shen, Remi Adelaiye-Ogala, Nur P. Damayanti, Ashley R. Orillion, May Elbanna
Supplementary Figure S9 shows TIE2 and macrophage markers expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e7449173a57b557eaa1044023411f0e
https://doi.org/10.1158/1535-7163.22506595
https://doi.org/10.1158/1535-7163.22506595
Autor:
Roberto Pili, Georg A. Bjarnason, Sreenivasulu Chintala, Michael Buck, Gerald Fetterly, Joshua Prey, Ashley Orillion, Sheng-Yu Ku, Swathi Ramakrishnan, Li Shen, Dylan Conroy, Maria Tsompana, Jonathan Bard, Paula Sotomayor, Kiersten Marie Miles, Eric Ciamporcero, Remi Adelaiye
Supplementary Fig 4. Intratumoral and plasma sunitinib concentrations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46a94fe1e8fefbc650c4999b4154e67e
https://doi.org/10.1158/1535-7163.22501786
https://doi.org/10.1158/1535-7163.22501786
Autor:
Roberto Pili, Georg A. Bjarnason, Sreenivasulu Chintala, Michael Buck, Gerald Fetterly, Joshua Prey, Ashley Orillion, Sheng-Yu Ku, Swathi Ramakrishnan, Li Shen, Dylan Conroy, Maria Tsompana, Jonathan Bard, Paula Sotomayor, Kiersten Marie Miles, Eric Ciamporcero, Remi Adelaiye
Supplementary Figure legend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e51e8f21d996bd092f1da2d7a4cb888
https://doi.org/10.1158/1535-7163.22501765
https://doi.org/10.1158/1535-7163.22501765
Autor:
Roberto Pili, Georg A. Bjarnason, Sreenivasulu Chintala, Michael Buck, Gerald Fetterly, Joshua Prey, Ashley Orillion, Sheng-Yu Ku, Swathi Ramakrishnan, Li Shen, Dylan Conroy, Maria Tsompana, Jonathan Bard, Paula Sotomayor, Kiersten Marie Miles, Eric Ciamporcero, Remi Adelaiye
Supplementary Fig. 7. EZH2 and E-cadherin mRNA expression in 786-0shRNA scramble, 786-0shEZH2 (clone a and d), and 786-0 treated with GSK126
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1161f8f2a1ff602e7d306f6a66d7c676
https://doi.org/10.1158/1535-7163.22501768.v1
https://doi.org/10.1158/1535-7163.22501768.v1
Autor:
Roberto Pili, Georg A. Bjarnason, Sreenivasulu Chintala, Michael Buck, Gerald Fetterly, Joshua Prey, Ashley Orillion, Sheng-Yu Ku, Swathi Ramakrishnan, Li Shen, Dylan Conroy, Maria Tsompana, Jonathan Bard, Paula Sotomayor, Kiersten Marie Miles, Eric Ciamporcero, Remi Adelaiye
Supplementary Fig. 2. Tumor growth of RP-R-01 ccRCC xenograft treated with sunitinib and associated changes in EZH2, H3K27me3 and E-cadherin expression.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b482ec93c58fb1cf3c3d502b6867c156
https://doi.org/10.1158/1535-7163.22501777.v1
https://doi.org/10.1158/1535-7163.22501777.v1