Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Sheng Hui Lan"'
Autor:
Pei‐Wen Lin, Man‐Ling Chu, Yu‐Wen Liu, Yu‐Cing Chen, Yao‐Hsiang Shih, Sheng‐Hui Lan, Shang‐Ying Wu, I‐Ying Kuo, Hong‐Yi Chang, Hsiao‐Sheng Liu, Ying‐Ray Lee
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 642-649 (2024)
Abstract Autophagy can be classified as degradative and secretory based on distinct functions. The small GTPase proteins Rab8a and Rab37 are responsible for secretory autophagy‐mediated exocytosis of IL‐1β, insulin, and TIMP1 (tissue inhibitor o
Externí odkaz:
https://doaj.org/article/e258c7ae7ddd4ed3a3137a5a976dbe9c
Autor:
Hsiao‐Sheng Liu, Yin‐Ping Wang, Pei‐Wen Lin, Man‐Ling Chu, Sheng‐Hui Lan, Shan‐Ying Wu, Ying‐Ray Lee, Hong‐Yi Chang
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 40, Iss 7, Pp 631-641 (2024)
Abstract Autophagy is a self‐recycling machinery to maintain cellular homeostasis by degrading harmful materials in the cell. Autophagy‐related gene 5 (Atg5) is required for autophagosome maturation. However, the role of Atg5 in tumorigenesis und
Externí odkaz:
https://doaj.org/article/f842293ee22c4ac499453b39c2812390
Autor:
Man‐Ling Chu, Pei‐Wen Lin, Yu‐Wen Liu, Shan‐Ying Wu, Sheng‐Hui Lan, Chun‐Li Su, Hsiao‐Sheng Liu
Publikováno v:
Kaohsiung Journal of Medical Sciences, Vol 39, Iss 5, Pp 489-500 (2023)
Abstract Formosanin C (FC) is a natural compound extracted from Paris formosana Hayata with anticancer activity. FC induces both autophagy and apoptosis in human lung cancer cells. FC‐induced depolarization of mitochondrial membrane potential (MMP)
Externí odkaz:
https://doaj.org/article/4d919fd7ccc7474c9776b02b6282a07f
Autor:
Shan-Ying Wu, Jia-Wen Chen, Hsi-Yu Liu, Yi-Ching Wang, Yeh-Shiu Chu, Chi-Ying Huang, Kai-Ying Lan, Hsiao-Sheng Liu, Sheng-Hui Lan
Publikováno v:
Journal of Biomedical Science, Vol 29, Iss 1, Pp 1-18 (2022)
Abstract Background Rab37-mediated exocytosis of tissue inhibitor of metalloproteinase 1 (TIMP1), an inflammatory cytokine, under serum-depleted conditions which leads to suppression of lung cancer cell metastasis has been reported. Starvation is als
Externí odkaz:
https://doaj.org/article/7903b545231c4c54a14c56fea5a03f20
Autor:
Hong-Yi Chang, Chi-Hua Lee, Yi-Syuan Li, Jing-Tong Huang, Sheng-Hui Lan, Yi-Fang Wang, Wu-Wei Lai, Yi-Ching Wang, Yan-Ju Lin, Hsiao-Sheng Liu, Hung-Chi Cheng
Publikováno v:
Journal of Biomedical Science, Vol 27, Iss 1, Pp 1-14 (2020)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is widely prevalent in Taiwan, and high metastatic spread of ESCC leads to poor survival rate. Fibronectin (FN) assembly on the cell membrane may induce ESCC mobility. MicroRNAs (MiRNAs) a
Externí odkaz:
https://doaj.org/article/7d791233644e407588c6f294fa56885a
Autor:
Sheng-Hui Lan, Shu-Ching Lin, Wei-Chen Wang, Yu-Chan Yang, Jenq-Chang Lee, Pei-Wen Lin, Man-Ling Chu, Kai-Ying Lan, Roberto Zuchini, Hsiao-Sheng Liu, Shan-Ying Wu
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Many studies reported that microRNAs (miRNAs) target autophagy-related genes to affect carcinogenesis, however, autophagy-deficiency-related miRNA dysfunction in cancer development remains poorly explored. During autophagic progression, we identified
Externí odkaz:
https://doaj.org/article/d2597a9e82fa4b389240004411da9254
Autor:
Chien-An Chu, Chung-Ta Lee, Jenq-Chang Lee, Yi-Wen Wang, Ching-Tang Huang, Sheng-Hui Lan, Peng-Chan Lin, Bo-Wen Lin, Yu-Feng Tian, Hsiao-Sheng Liu, Nan-Haw Chow
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 270-281 (2019)
Background: In our preliminary screening, expression of miR-338-5p was found to be higher in primary colorectal cancer (CRC) with metastasis. The autophagy related gene- phosphatidylinositol 3-kinase, catalytic subunit type 3 (PIK3C3) appeared to be
Externí odkaz:
https://doaj.org/article/d76130558dfb4fbbae0b98e63c873fb3
Autor:
Shan-Ying Wu, Hung-Tsung Wu, Yi-Ching Wang, Chih-Jen Chang, Yan-Shen Shan, Shang-Rung Wu, Yen-Chi Chiu, Chia-Lang Hsu, Hsueh-Fen Juan, Kai-Ying Lan, Chi-Wen Chu, Ying-Ray Lee, Sheng-Hui Lan, Hsiao-Sheng Liu
Publikováno v:
Autophagy. 19:1239-1257
High blood glucose is one of the risk factors for metabolic disease and INS (insulin) is the key regulatory hormone for glucose homeostasis. Hypoinsulinemia accompanied with hyperglycemia was diagnosed in mice with pancreatic β-cells exhibiting auto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90a202bf78ea7653cb6dc2e0a8c6f72
https://doi.org/10.1080/15548627.2022.2123098
https://doi.org/10.1080/15548627.2022.2123098
Autor:
Shan-Ying Wu, Yu-Lun Chen, Ying-Ray Lee, Chiou-Feng Lin, Sheng-Hui Lan, Kai-Ying Lan, Man-Ling Chu, Pei-Wen Lin, Zong-Lin Yang, Yen-Hsu Chen, Wen-Hung Wang, Hsiao-Sheng Liu
Publikováno v:
Viruses, Vol 13, Iss 10, p 2034 (2021)
Autophagic machinery is involved in selective and non-selective recruitment as well as degradation or exocytosis of cargoes, including pathogens. Dengue virus (DENV) infectioninduces autophagy that enhances virus replication and vesicle release to ev
Externí odkaz:
https://doaj.org/article/6504f4ad4c0444fa8196ba9740457ade
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-10 (2017)
Abstract Background Arsenic is a widely distributed metalloid compound that has biphasic effects on cultured cells. In large doses, arsenic can be toxic enough to trigger cell death. In smaller amounts, non-toxic doses may promote cell proliferation
Externí odkaz:
https://doaj.org/article/29e9bc058c1a4388be1a0e5511038537