Dual Effects of Let-7b in the Early Stage of Hepatitis C Virus Infection

Autor: Yung-Ju Yeh, His-Yuan Huang, Hsien Da Huang, Sheng Da Hsu, Ju-Chien Cheng, Michael M. C. Lai, Ching-Ping Tseng

Publikováno v: J Virol

MicroRNA let-7b expression is induced by infection of hepatitis C virus (HCV) and is involved in the regulation of HCV replication by directly targeting the HCV genome. The current study demonstrated that let-7b directly targets negative regulators o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f982c1189e682cdffeb94f7e08c1b1
https://doi.org/10.1128/jvi.01800-20

Honeysuckle aqueous extract and induced let-7a suppress dengue virus type 2 replication and pathogenesis

Autor: Hsiao Sheng Liu, Ying-Ray Lee, Sheng Da Hsu, Hao Zhang, Xiao Ming Ruan, Siao Fen Yeh, Chang Chi Hsieh, Dai Di Gan, Trai Ming Yeh, Yee Shin Lin, Hsien Da Huang

Publikováno v: Journal of Ethnopharmacology. 198:109-121

Ethnopharmacological relevance Honeysuckle ( Lonicera japonica Thunb.), a traditional Chinese herb, has widely been used to treat pathogen infection. However, the underlying-mechanism remains elusive. Aims of the study To reveal the host microRNA (mi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::453aeb3e2454d413648c35b781f96067
https://doi.org/10.1016/j.jep.2016.12.049

Integrated analyses to reconstruct microRNAmediated regulatory networks in mouse liver using high-throughput profiling.

Autor: Sheng-Da Hsu^1,2,3 (AUTHOR), Hsi-Yuan Huang^1,2,3 (AUTHOR), Chih-Hung Chou^1,3 (AUTHOR), Yi-Ming Sun⁴ (AUTHOR), Ming-Ta Hsu⁵ (AUTHOR), Ann-Ping Tsou^5,6 (AUTHOR) annptsou@gmail.com

Publikováno v: BMC Genomics. 2015 Suppl 2, Vol. 16, p1-16. 16p. 3 Charts, 6 Graphs.

miRTarBase 2016: updates to the experimentally validated miRNA-target interactions database

Autor: Nai-Wen Chang, Chun-Chi Liu, Tzi Ren Tsai, Chung Yuan Pai, Sirjana Shrestha, Ting-Yen Wei, Chi Dung Yang, Pin Rong Chen, Wen-Liang Chen, Ting Yan Jian, Sheng Da Hsu, Hsiao Chin Hong, Siang Jyun Tu, Wei Hsiang Lee, Hsin Yi Wu, Shun Long Weng, Chih Hung Chou, Chun San Tai, Hsien Da Huang, Wen-Lian Hsu, Nai Chieh Lin, Kuang-Wen Liao, Yu Ling Lin, Chia-Yen Huang, Hsin Tzu Huang, Tzu Ling Yang, Shu Yi Ho

Publikováno v: Nucleic Acids Research

MicroRNAs (miRNAs) are small non-coding RNAs of approximately 22 nucleotides, which negatively regulate the gene expression at the post-transcriptional level. This study describes an update of the miRTarBase (http://miRTarBase.mbc.nctu.edu.tw/) that

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abff11735ed4b328ba9fa4c6457be6a
https://doi.org/10.1093/nar/gkv1258

Integrated MicroRNA-mRNA Analysis Reveals miR-204 Inhibits Cell Proliferation in Gastric Cancer by Targeting CKS1B, CXCL1 and GPRC5A

Autor: Wei Yun Huang, Men Yee Chiew, Meng Lin Lee, Sheng Da Hsu, Chih Hung Chou, Chi Dung Yang, Shun Long Weng, Wen-Liang Chen, Chung Chu Chen, Sirjana Shrestha, Hsien Da Huang, Yi An Chang, Chun San Tai, Yi-Chang Chen, Hsiao Chin Hong

Publikováno v: International Journal of Molecular Sciences
International Journal of Molecular Sciences; Volume 19; Issue 1; Pages: 87
International Journal of Molecular Sciences, Vol 19, Iss 1, p 87 (2017)

Gastric cancer (GC) is the second most frequent cause of cancer-related deaths worldwide. MicroRNAs are single-stranded RNA molecules of 21–23 nucleotides that regulate target gene expression through specific base-pairing interactions between miRNA

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a87b104ba2361e8dbef447e794cf90c
https://pubmed.ncbi.nlm.nih.gov/29283424