Zobrazeno 1 - 10
of 381
pro vyhledávání: '"Sheng Chu Kuo"'
Autor:
Yi-Fong Chen, Bashir Lawal, Li-Jiau Huang, Sheng-Chu Kuo, Maryam Rachmawati Sumitra, Ntlotlang Mokgautsi, Hung-Yun Lin, Hsu-Shan Huang
Publikováno v:
Molecules, Vol 28, Iss 2, p 555 (2023)
Our previous study found that 2-phenyl-4-quinolone (2-PQ) derivatives are antimitotic agents, and we adopted the drug design concept of scaffold hopping to replace the 2-aromatic ring of 2-PQs with a 4-aromatic ring, representing 4-phenyl-2-quinolone
Externí odkaz:
https://doaj.org/article/1ed60b03c4ea474186cda1f3f11edc1b
Autor:
Der-Yen Lee, Hui-Yi Lin, Manickavasakam Ramasamy, Sheng-Chu Kuo, Pei-Chih Lee, Min-Tsang Hsieh
Publikováno v:
Molecules, Vol 26, Iss 22, p 7050 (2021)
Natural phenolic products from herbal medicines and dietary plants constitute the main source of lead compounds for the development of the new drug. 4,4-Dimethylcurcumin (DMCU) is a synthetic curcumin derivative and exhibits anticancer activities aga
Externí odkaz:
https://doaj.org/article/ca82165300ea4a049a17af6cc97b4170
Autor:
Yih-Dih Cheng, Chi‑Cheng Lu, Yuan-Man Hsu, Fuu-Jen Tsai, Da-Tian Bau, Shih-Chang Tsai, Ching-Chang Cheng, Jen-Jyh Lin, Yuang-Yu Huang, Yu-Ning Juan, Yu-Jen Chiu, Sheng-Chu Kuo, Jai-Sing Yang, Lii-Tzu Wu
Publikováno v:
BioMedicine. 12:56-71
Autor:
Sio-Hong Lam, Hui-Kang Liu, Shih-Yuan Chung, Jia-Ling Chang, Mao-Xuan Hong, Sheng-Chu Kuo, Chih-Chuang Liaw
Publikováno v:
Journal of Natural Products.
Autor:
Shin-Hun Juang, Min-Tsang Hsieh, Pei-Ling Hsu, Ju-Ling Chen, Hui-Kang Liu, Fong-Pin Liang, Sheng-Chu Kuo, Chen-Yuan Chiu, Shing-Hwa Liu, Chen-Hsi Chou, Tian-Shung Wu, Hsin-Yi Hung
Publikováno v:
Molecules, Vol 26, Iss 1, p 164 (2020)
Constitutive androstane receptor (CAR) activation has found to ameliorate diabetes in animal models. However, no CAR agonists are available clinically. Therefore, a safe and effective CAR activator would be an alternative option. In this study, sixty
Externí odkaz:
https://doaj.org/article/30bfc32eb7534be8a4d05ff37022e91c
Autor:
Der-Yen Lee, Yu-Chi Hou, Jai-Sing Yang, Hui-Yi Lin, Tsu-Yuan Chang, Kuo-Hsiung Lee, Sheng-Chu Kuo, Min-Tsang Hsieh
Publikováno v:
Molecules, Vol 25, Iss 3, p 479 (2020)
Compound 1 is a curcumin di-O-2,2-bis(hydroxymethyl)propionate that shows significant in vitro and in vivo inhibitory activity against MDA-MB-231 cells with eight to ten-fold higher potency than curcumin. Here, we modified the α-position (C-4 positi
Externí odkaz:
https://doaj.org/article/fe2a24688e6b4f0b8dee0f3739064ea8
Publikováno v:
Journal of Functional Foods, Vol 12, Iss , Pp 439-449 (2015)
Curcuminoids, including curcumin (CUR), demethoxycurcumin (DMC), and bisdemethoxycurcumin (BDMC), show the maximum absorption wavelength near blue light. Photodynamic therapy (PDT) has been developed as a therapeutic modality, which could induce cell
Externí odkaz:
https://doaj.org/article/511ed6e8eef3411fa4bc237e8cf6f409
Autor:
Tung-Ho Wu, Yung-Yi Cheng, Chao-Jung Chen, Lean-Teik Ng, Li-Chen Chou, Li-Jiau Huang, Yung-Husan Chen, Sheng-Chu Kuo, Mohamed El-Shazly, Yang-Chang Wu, Fang-Rong Chang, Chih-Chuang Liaw
Publikováno v:
Molecules, Vol 19, Iss 2, Pp 2049-2060 (2014)
Three new clerodane diterpenes, (4→2)-abeo-cleroda-2,13E-dien-2,14-dioic acid (1), (4→2)-abeo-2,13-diformyl-cleroda-2,13E-dien-14-oic acid (2), and 16(R&S)- methoxycleroda-4(18),13-dien-15,16-olide (3), were isolated from the unripe fruit of Poly
Externí odkaz:
https://doaj.org/article/38311024fd584298a255bd51103ab67e
Autor:
Xuan Hong, Min-Tsang Hsieh, Tzu-Yu Tseng, Hui-Yi Lin, Hung-Chih Chang, Sir-Theng Yau, Wei-Chung Cheng, Baozhen Ke, Hsiao-Hui Liao, Chih-Ying Wu, An-An Liu, Meei-Maan Wu, Kuo-Yen Huang, Pan-Chyr Yang, Sheng-Chu Kuo, Mien-Chie Hung, Pei-Chih Lee
Publikováno v:
Journal of Biological Chemistry. :104814
Autor:
Jai Sing Yang, Mann-Jen Hour, Yu-Jen Chiu, Hai-Anh Ha, Ching-Chang Cheng, Yu‑Shiang Lo, Yih-Dih Cheng, Shih Chang Tsai, Chih-Wei Fu, Jo Hua Chiang, Jen Jyh Lin, Sheng-Chu Kuo, Fuu Jen Tsai, Yu‑Ning Juan
Publikováno v:
BioMedicine. 11:1-18
Coronavirus disease 2019 (COVID-19) has been spreading worldwide with a mind-boggling speed According to a statement from World Health Organization (WHO), COVID-19 has infected more than six billions people and caused more than one and half million p