Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Sheng‐Xiao Zhang"'
Autor:
Qin-Yi Su, Yan Zhang, Dan Qiao, Xia Song, Yang Shi, Rong-Qi Li, Ying-Fang Zhang, Sheng-Xiao Zhang
Publikováno v:
Exploration of Medicine, Vol 5, Iss 6, Pp 709-719 (2024)
Background: Rheumatoid arthritis (RA) is an autoimmune joint disease with systemic manifestations. Emerging evidence implicates the gut microbiota in the pathophysiology of RA. However, the specific changes in the gut microbiota in RA patients remain
Externí odkaz:
https://doaj.org/article/c65fe8d562004717bdd41a915072994f
Autor:
Qin-Yi Su, Jing Luo, Yan Zhang, Qian Li, Zhong-Qing Jiang, Zi-Rong Wen, Yu-Ying Wang, Mo-Ran Shi, Sheng-Xiao Zhang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-9 (2024)
Abstract Background Difficult-to-treat Rheumatoid arthritis (D2T RA) is primarily characterised by failure of at least two different mechanism of action biologic/targeted synthetic disease-modifying antirheumatic drug (DMARDs) with evidence of active
Externí odkaz:
https://doaj.org/article/5ab7ddb6be99449abd2c368578eb91c6
Autor:
Fen-Ping Lian, Fen Zhang, Chun-Miao Zhao, Xu-Xia Wang, Yu-Jie Bu, Xing Cen, Gui-Fang Zhao, Sheng-Xiao Zhang, Jun-Wei Chen
Publikováno v:
BMC Immunology, Vol 25, Iss 1, Pp 1-9 (2024)
Abstract Background Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by disturbance of pro-inflammatory and anti-inflammatory lymphocytes. Growing evidence shown that gut microbiota participated in the occurrence and developm
Externí odkaz:
https://doaj.org/article/f07651d383ea421ea13d928dda95aacd
Autor:
Qin-Yi Su, Yan Zhang, Dan Qiao, Xia Song, Yang Shi, Zhe Wang, Chen-Yan Wang, Sheng-Xiao Zhang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
BackgroundAnkylosing spondylitis (AS) is a connective tissue disease that primarily affects spinal joints, peripheral joints, and paravertebral soft tissues, leading to joint stiffness and spinal deformity. Growing evidence has implicated gut microbi
Externí odkaz:
https://doaj.org/article/f30437f0b58b43f389568ab5d597174a
Autor:
Ting Cheng, Jia-Lin Hou, Zi-Yi Han, Xin-Lei Geng, Yao-Chen Zhang, Ke-Yi Fan, Liu Liu, He-Yi Zhang, Yue-Hong Huo, Xiao-Feng Li, Sheng-Xiao Zhang
Publikováno v:
Experimental Gerontology, Vol 191, Iss , Pp 112434- (2024)
Background: Observational evidence suggests that type 1 diabetes mellitus (T1DM) is associated with the risk of osteoporosis (OP). Nevertheless, it is not apparent whether these correlations indicate a causal relationship. To elucidate the causal rel
Externí odkaz:
https://doaj.org/article/d0d945d28a2a48e0958470e4829eb77e
Autor:
Qin-Yi Su, Hao-Nan Zhou, Guo-Mei Xia, Rui-Yuan Zhang, Hong-Yuan Tian, Chang Su, Yu-Xin Liu, He-Yi Zhang, Ting Cheng, Yue-Hong Huo, Qian Li, Sheng-Xiao Zhang
Publikováno v:
Rheumatology and Therapy, Vol 11, Iss 2, Pp 227-237 (2024)
Abstract Introduction Currently, the cause of psoriatic arthritis (PsA) is unknown, and the effectiveness of current drug treatments is unsatisfactory. In March 2019, the US Food and Drug Administration (FDA) approved risankizumab, a humanized immuno
Externí odkaz:
https://doaj.org/article/02e8c4b1e856444593e5ab8c9f52f166
Autor:
Rong Zhao, Yi-Wen Zhang, Jin-Cheng Guo, Jun Qiao, Shan Song, Ting-Ting Zhang, He-Yi Zhang, Sheng-Xiao Zhang
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Background/purpose: Previous epidemiological studies have associated interstitial lung disease (ILD) with rheumatoid arthritis (RA), yet the causality of this relationship remains uncertain. This study aimed to investigate the genetic causal link bet
Externí odkaz:
https://doaj.org/article/34f5e339affc43bda56bdbe5bf868a99
Autor:
Qin-Yi Su, Huan-Cheng Li, Xiao-Jing Jiang, Zhong-Qing Jiang, Yan Zhang, He-Yi Zhang, Sheng-Xiao Zhang
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 174, Iss , Pp 116440- (2024)
Rheumatoid arthritis (RA) is a complex autoimmune inflammatory rheumatic disease characterized by an imbalance between immunological reactivity and immune tolerance. Regulatory T cells (Tregs), which play a crucial role in controlling ongoing autoimm
Externí odkaz:
https://doaj.org/article/0948e788335f42bf9dbc3dfac6ec179b
Autor:
Sheng-Xiao Zhang, Hao-Ran Chen, Jia Wang, Hong-Fang Shao, Ting Cheng, Ruo-Meng Pei, Qin-Yi Su, He-Yi Zhang, Xiao-Feng Li
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundImmunotherapy targeting factors related to immune imbalance has been widely employed for RA treatment. This study aimed to evaluate the efficacy and safety of low-dose interleukin (IL)-2 combined with tocilizumab (TCZ), a biologics targetin
Externí odkaz:
https://doaj.org/article/193bff2f11244cda91d0ec1adc9d4576
Autor:
Rong Zhao, Yi-wen Zhang, Jia-yuan Yao, Jun Qiao, Shan Song, Sheng-xiao Zhang, Cai-hong Wang, Xiao-feng Li
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-10 (2023)
Abstract Background The pathogenesis of rheumatoid arthritis (RA) is an immune imbalance, in which various inflammatory immune cells and pro-inflammatory factors are involved. Interleukin-17 (IL-17), a potent pro-inflammatory cytokine, has been found
Externí odkaz:
https://doaj.org/article/af0d6a8d790e4bf8b1f5e7a4d85c5f9c