Výsledky vyhledávání - "Sheneil K. Black"

Akademický článek

Self‐Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design

Autor: Michelle L. Bookstaver, Qin Zeng, Robert S. Oakes, Senta M. Kapnick, Vikas Saxena, Camilla Edwards, Nishedhya Venkataraman, Sheneil K. Black, Xiangbin Zeng, Eugene Froimchuk, Thomas Gebhardt, Jonathan S. Bromberg, Christopher M. Jewell

Publikováno v: Advanced Science, Vol 10, Iss 1, Pp n/a-n/a (2023)

Abstract Recent clinical studies show activating multiple innate immune pathways drives robust responses in infection and cancer. Biomaterials offer useful features to deliver multiple cargos, but add translational complexity and intrinsic immune sig

Externí odkaz: https://doaj.org/article/07ac2af086f849e8bda97b396a8fbfd9

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Impact of Excipients on Stability of Polymer Microparticles for Autoimmune Therapy

Autor: Emily A. Gosselin, Maeesha Noshin, Sheneil K. Black, Christopher M. Jewell

Publikováno v: Frontiers in Bioengineering and Biotechnology, Vol 8 (2021)

Therapies for autoimmune diseases such as multiple sclerosis and diabetes are not curative and cause significant challenges for patients. These include frequent, continued treatments required throughout the lifetime of the patient, as well as increas

Externí odkaz: https://doaj.org/article/7365d217c8eb4617914f2dc16a4d4fdf

Zobrazit plný text záznamu

Self-Assembly of Immune Signals to Program Innate Immunity through Rational Adjuvant Design

Publikováno v: Advanced science (Weinheim, Baden-Wurttemberg, Germany).

Recent clinical studies show activating multiple innate immune pathways drives robust responses in infection and cancer. Biomaterials offer useful features to deliver multiple cargos, but add translational complexity and intrinsic immune signatures t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76d9657f27248d361e0c92e32f1223e
https://pubmed.ncbi.nlm.nih.gov/36373708

Zobrazit plný text záznamu

Microfluidics-generated immunomodulatory nanoparticles and formulation-dependent effects on lipopolysaccharide-induced macrophage inflammation

Autor: Ryan M. Pearson, Jacob Shaw, Brianna L. Scotland, Nhu Truong, Sheneil K Black

Publikováno v: AAPS J

Nanoparticles (NPs) have emerged as a highly useful and clinically translatable drug delivery platform for vast therapeutic payloads. Through the precise tuning of their physicochemical properties, NPs can be engineered to exhibit controlled drug rel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c605a3fc45ccf350124e748a28a8fb65
https://europepmc.org/articles/PMC8728808/

Zobrazit plný text záznamu

Exploiting Rational Assembly to Map Distinct Roles of Regulatory Cues during Autoimmune Therapy

Autor: Eugene Froimchuk, Xiangbin Zeng, Sheneil K Black, Robert S. Oakes, Senta M. Kapnick, Lisa H. Tostanoski, Christopher M. Jewell

Publikováno v: ACS Nano

Autoimmune diseases like multiple sclerosis (MS), type 1 diabetes, and lupus occur when the immune system attacks host tissue. Immunotherapies that promote selective tolerance without suppressing normal immune function are of tremendous interest. Her

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f192a3365d5396692ea3ff5a591bb462
https://pubmed.ncbi.nlm.nih.gov/33645967

Zobrazit plný text záznamu

Leveraging the Modularity of Biomaterial Carriers to Tune Immune Responses

Autor: Christopher M. Jewell, Sheneil K Black, Shannon J. Tsai

Publikováno v: Adv Funct Mater

Biomaterial carriers offer modular features to control the delivery and presentation of vaccines and immunotherapies. This tunability is a distinct capability of biomaterials. Understanding how tunable material features impact immune responses is imp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee229a90de2f6563c8f8332b21b0355f
https://doi.org/10.1002/adfm.202004119

Zobrazit plný text záznamu