Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shendra R. Miller"'
Autor:
Vanessa Pirrone, Shendra R. Miller, Simon Cocklin, Sabine Baxter, Ferit Tuzer, Irwin Chaiken, Judith M. LaLonde, M. Umashankara, Jeffrey C. Klein, Navneet Jawanda, Fred C. Krebs, Arne Schön, Amos B. Smith, Joseph Sodroski, Ernesto Freire, Navid Madani, Hosahudya N. Gopi, Isaac Zentner
Publikováno v:
Journal of Medicinal Chemistry. 51:2638-2647
Structure-activity correlations were investigated for substituted peptide conjugates that function as dual receptor site antagonists of HIV-1 gp120. A series of peptide conjugates were constructed via click reaction of both aryl and alkyl acetylenes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f3bd9ceed55edf3bccdc7ccc21887b3
https://doi.org/10.1021/jm070814r
https://doi.org/10.1021/jm070814r
Autor:
Mohamed E. Labib, Robert F. Rando, Fred C. Krebs, Sakae Shin-Etsu Chemical Co. Ltd. Obara, Mark C. Osterling, Marie K. Mankowski, Hiroyasu Kokubo, Brian Wigdahl, Mary L Ferguson, Shendra R. Miller
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:3081-3089
Recent studies of cellulose-based polymers substituted with carboxylic acids like cellulose acetate phthalate (CAP) have demonstrated the utility of using carboxylic acid groups instead of the more common sulfate or sulfonate moieties. However, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa718c8d8b9b453627f2d22cae3ec341
https://doi.org/10.1128/aac.01609-05
https://doi.org/10.1128/aac.01609-05
Autor:
Luke A. Pallansch, Ena Bromley, Mary K. Howett, Brigitte E. Beer, Patricia A. Welsh, Robert W. Buckheit, Brian Wigdahl, Nicola Richardson-Harman, Bradley J. Catalone, Carol Lackman-Smith, Fred C. Krebs, Shendra R. Miller, Gustavo F. Doncel, Clay Osterling, Robin J. Shattock, Karen M. Watson, Jim A. Turpin, James E. Cummins, Charlene S. Dezzutti, Patricia Reichelderfer, Marie K. Mankowski, Patricia S. Fletcher
Publikováno v:
Antimicrobial Agents and Chemotherapy. 50:713-723
The first product to be clinically evaluated as a microbicide contained the nonionic surfactant nonoxynol-9 (nonylphenoxypolyethoxyethanol; N-9). Many laboratories have used N-9 as a control compound for microbicide assays. However, no published comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71945f46c22cf2a64a2b867425893553
https://doi.org/10.1128/aac.50.2.713-723.2006
https://doi.org/10.1128/aac.50.2.713-723.2006
Autor:
Brian Wigdahl, Shendra R. Miller, Tina Kish-Catalone, Bradley J. Catalone, Daniel Malamud, Mary K. Howett, Mary L Ferguson, Nina Thakkar, Fred C. Krebs
Publikováno v:
Biomedicine & Pharmacotherapy. 59:430-437
C31G, which has potent activity against the human immunodeficiency virus type 1 (HIV-1) and an established record of safety in animal studies and human trials, is a microbicidal agent comprised of a buffered equimolar mixture of two amphoteric, surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177693239defce1568f1400ddbcaf00e
https://doi.org/10.1016/j.biopha.2005.07.008
https://doi.org/10.1016/j.biopha.2005.07.008
Autor:
Nina Thakkar, Tina Kish-Catalone, Mary K. Howett, Brian Wigdahl, Bradley J. Catalone, Shendra R. Miller, Daniel Malamud, Fred C. Krebs, Mary L Ferguson
Publikováno v:
Biomedicine & Pharmacotherapy. 59:460-468
Comparative assays of in vitro cytotoxicity using nonoxynol-9 (N-9) and the candidate microbicides C31G and sodium dodecyl sulfate (SDS) demonstrated that these agents, which are, respectively, characterized as nonionic, amphoteric, and anionic surfa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6cde8f3c76e17c38702c1018addbd72
https://doi.org/10.1016/j.biopha.2005.07.009
https://doi.org/10.1016/j.biopha.2005.07.009
Autor:
Robert F. Rando, Shendra R. Miller, Mary L Ferguson, Brian Wigdahl, Fred C. Krebs, Mohamed E. Labib
Publikováno v:
Biomedicine & Pharmacotherapy. 59:438-445
Polyhexamethylene biguanide (PHMB) is a polybiguanide (PBG) oligomer with antimicrobial activity that is used extensively and safely as a disinfectant. The reported mechanism of PHMB antimicrobial activity, which involves interactions with cell membr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::809d1b48c2f974c7e55efccd537267da
https://doi.org/10.1016/j.biopha.2005.07.007
https://doi.org/10.1016/j.biopha.2005.07.007
Publikováno v:
Antiviral Research. 43:157-173
A highly desirable approach to prevention of human immunodeficiency virus type 1 (HIV-1) transmission during sexual intercourse is the development of nontoxic, topical, broad spectrum microbicides effective against transmission of cell-associated and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b5aaf22a3808fc357037ccc0e53d91
https://doi.org/10.1016/s0166-3542(99)00044-3
https://doi.org/10.1016/s0166-3542(99)00044-3
Autor:
Shendra R. Miller, Robert F. Rando, Fred C. Krebs, Lori Schlipf, Mary L Ferguson, Brian Wigdahl, Mohamed E. Labib, Nina Thakkar
Publikováno v:
Retrovirology. 2
Microbicides, which are products capable of reducing or eliminating the risk of HIV-1 sexual transmission, are urgently needed to combat the global spread of HIV-1. Our efforts in this area are focused on the preclinical development of the polybiguan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68b26bc8e606602f5f46558bbe6cf0fe
https://doi.org/10.1186/1742-4690-2-s1-p94
https://doi.org/10.1186/1742-4690-2-s1-p94
Use of the Synthetic Copolymer PSMA as a Component in a Combination Microbicide Active Against HIV-1
Autor:
Mohamed E. Labib, Mary L Ferguson, Robert F. Rando, Fred C. Krebs, Brian Wigdahl, Lori Schlipf, Jin Qian, Shendra R. Miller
Publikováno v:
Retrovirology, Vol 2, Iss Suppl 1, p S96 (2005)
The remarkable successes achieved using combination therapy to treat systemic human immunodeficiency virus type 1 (HIV-1) infection suggest that combination microbicides, which include two or more active ingredients, may also provide a particularly e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07e00a0e46218a6ac410d9f86881c470
https://doi.org/10.1186/1742-4690-2-s1-s96
https://doi.org/10.1186/1742-4690-2-s1-s96
Autor:
Mohamed E. Labib, Shendra R. Miller, Vanessa Pirrone, Robert F. Rando, Fred C. Krebs, Brian Wigdahl, Mary L Ferguson, Lori Schlipf
Publikováno v:
Retrovirology, Vol 2, Iss Suppl 1, p S95 (2005)
Topical microbicides that reduce or eliminate the risk of human immunodeficiency virus type 1 (HIV-1) sexual transmission must function effectively within the cervicovaginal environment where multiple factors may impact the efficacy of the active age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b20afa458b29b39d0c625701a065306
https://doi.org/10.1186/1742-4690-2-s1-s95
https://doi.org/10.1186/1742-4690-2-s1-s95