Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Shen-Hsing Hsu"'
Publikováno v:
Biomedical Journal, Vol 46, Iss 4, Pp 100595- (2023)
Leptospirosis is a neglected bacterial disease caused by leptospiral infection that carries a substantial mortality risk in severe cases. Research has shown that acute, chronic, and asymptomatic leptospiral infections are closely linked to acute and
Externí odkaz:
https://doaj.org/article/f19b7f913c5743bda4ff78b790fe141c
Autor:
Li-Fang Chou, Ting-Wen Chen, Huang-Yu Yang, Ya-Chung Tian, Ming-Yang Chang, Cheng-Chieh Hung, Chih-Ho Lai, Shen-Hsing Hsu, Chung-Ying Tsai, Yi-Ching Ko, Jang-Hau Lian, Chih-Wei Yang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 3 (2022)
ABSTRACT Leptospirosis, an emerging infectious disease caused by pathogenic Leptospira spp., occurs in ecoregions with heavy rainfall and has public health implications. Macrophages are the major anti-Leptospira phagocytes that infiltrate the kidneys
Externí odkaz:
https://doaj.org/article/3330caecaa3d4cfb93d2a7430eeceb8f
Autor:
Shen-Hsing Hsu, Ming-Yang Chang, Shih-Ming Lin, Yi-Ching Ko, Li-Feng Chou, Ya-Chung Tian, Cheng-Chieh Hung, Chih-Wei Yang
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Leptospirosis is an overlooked zoonotic disease caused by pathogenic Leptospira depended on virulence of Leptospira and the host–pathogen interaction. Kidney is the major organ infected by Leptospira which causes tubulointerstitial nephrit
Externí odkaz:
https://doaj.org/article/38354aa785de4392a55780792a68e3c6
Autor:
Shen-Hsing Hsu, Chih-Wei Yang
Publikováno v:
Membranes, Vol 12, Iss 3, p 300 (2022)
Leptospirosis is a widespread zoonosis that frequently occurs in tropical and subtropical countries. Leptospira enters the host through wounds or mucous membranes and spreads to the whole body through the blood, causing systemic infection. Kidneys ar
Externí odkaz:
https://doaj.org/article/0120b3ea8d3945aa83d24b122934962d
Autor:
Chung-Ying Tsai, Hsiang-Cheng Chi, Ren-Chin Wu, Cheng-Hao Weng, Tzong-Shyuan Tai, Chan-Yu Lin, Tai-Di Chen, Ya-Hui Wang, Li-Fang Chou, Shen-Hsing Hsu, Po-Hung Lin, See-Tong Pang, Huang-Yu Yang
Publikováno v:
Biomedicines, Vol 10, Iss 1, p 8 (2021)
In contrast to Western counties, the incidence of urothelial carcinoma (UC) remains mar-edly elevated in Taiwan. Regulatory T cells (Tregs) play a crucial role in limiting immune responses within the tumor microenvironment. To elucidate the relations
Externí odkaz:
https://doaj.org/article/d7da16ebe4764e3bab957c06c5066ae4
Autor:
Shen-Hsing Hsu, Cheng-Chieh Hung, Ming-Yang Chang, Yi-Ching Ko, Huang-Yu Yang, Hsiang-Hao Hsu, Ya-Chung Tian, Li-Fang Chou, Rong-Long Pan, Fan-Gang Tseng, Chih-Wei Yang
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Abstract Proteins belonging to the toll-like receptor (TLR) family, particularly TLR2, are the major components of innate immunity against Leptospira infection. The ligands for TLR2 harbor several conserved patterns such as lipidation molecules, leuc
Externí odkaz:
https://doaj.org/article/3ad6c781ed7149ee97f56bd56d6fc6b2
Autor:
Shen‐Hsing Hsu, Che‐Ting Wu, Yuh‐Ju Sun, Ming‐Yang Chang, Chien Li, Yi‐Ching Ko, Li‐Fang Chou, Chih‐Wei Yang
Publikováno v:
The FEBS Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0b1c12ff30ad28f6b027c2b9882ffe2
https://doi.org/10.1111/febs.16874
https://doi.org/10.1111/febs.16874
Autor:
Chung-Ying Tsai, Hsiang-Cheng Chi, Ren-Chin Wu, Cheng-Hao Weng, Tzong-Shyuan Tai, Chan-Yu Lin, Tai-Di Chen, Ya-Hui Wang, Li-Fang Chou, Shen-Hsing Hsu, Po-Hung Lin, See-Tong Pang, Huang-Yu Yang
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 8 (2022)
Biomedicines; Volume 10; Issue 1; Pages: 8
Biomedicines
Biomedicines; Volume 10; Issue 1; Pages: 8
Biomedicines
In contrast to Western counties, the incidence of urothelial carcinoma (UC) remains mar-edly elevated in Taiwan. Regulatory T cells (Tregs) play a crucial role in limiting immune responses within the tumor microenvironment. To elucidate the relations
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36dc6e2fc4e3b7bc77f00967534e10af
https://www.mdpi.com/2227-9059/10/1/8
https://www.mdpi.com/2227-9059/10/1/8
Metformin induces lactate accumulation and accelerates renal cyst progression in Pkd1-deficient mice
Autor:
Ming-Yang Chang, Chung-Ying Tsai, Li-Fang Chou, Shen-Hsing Hsu, Huang-Yu Yang, Cheng-Chieh Hung, Ya-Chung Tian, Albert C M Ong, Chih-Wei Yang
Publikováno v:
Human Molecular Genetics. 31:1560-1573
Metabolic reprogramming is a potential treatment strategy for autosomal dominant polycystic kidney disease (ADPKD). Metformin has been shown to inhibit the early stages of cyst formation in animal models. However, metformin can lead to lactic acidosi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::987e59923506b96c44a3c77fa54eae6c
https://doi.org/10.1093/hmg/ddab340
https://doi.org/10.1093/hmg/ddab340
Autor:
Ming-Yang Chang, Shen-Hsing Hsu, Li-Yi Ma, Li-Feng Chou, Cheng-Chieh Hung, Ya-Chung Tian, Chih-Wei Yang
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8499
The aberrant activation of the purinergic signaling pathway has been shown to promote cyst growth and fluid secretion in autosomal dominant polycystic kidney disease (ADPKD). Suramin is an anti-parasitic drug that has strong anti-purinergic propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::072b112252c440a481ae50e6bc2e667b
https://pubmed.ncbi.nlm.nih.gov/35955634
https://pubmed.ncbi.nlm.nih.gov/35955634