Zobrazeno 1 - 10
of 97
pro vyhledávání: '"Shen Ruling"'
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 56, Pp 1687-1698 (2024)
The Gt(ROSA)26Sor (ROSA26) and H11 loci are commonly used as safe harbors for the construction of targeted transgenic mice. However, it remains unclear whether these two loci have distinct effects on transgene expression. In this study, we insert thr
Externí odkaz:
https://doaj.org/article/1701b06e25594f5d9393c647733bc2f1
Autor:
LIANG Min, GUO Yang, WANG Jinjin, ZHU Mengyan, CHI Jun, CHEN Yanjuan, WANG Chengji, YU Zhilan, SHEN Ruling
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 44, Iss 1, Pp 42-51 (2024)
Objective The aim is to utilize CRISPR/Cas9 gene editing technology to construct Dmd gene mutant mice with a point mutation in exon 23 of the Dmd gene. Subsequently, the phenotypic changes of the mice in muscles and immune systems are analyzed and ve
Externí odkaz:
https://doaj.org/article/1152b6457674413fb72977efc60826ca
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 43, Iss 5, Pp 541-547 (2023)
Objective Construction of a negative control line for the Drosophila transgenic system based on ΦC31 integrase and vector plasmid pUASTattB to provide a more scientific negative control for transgenic Drosophila research experiments.Methods The vect
Externí odkaz:
https://doaj.org/article/06769877bc5949dfad80eca3aa3e1b53
Autor:
WANG Chengji, WANG Jue, WANG Haijie, LU Weisheng, SHI Yan, GU Zhengye, WAN Mingqiu, SHEN Ruling
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 43, Iss 5, Pp 574-578 (2023)
Objective Optimize the latex perfusion technique and apply it to the construction of a murine craniofacial venous vascular model. Methods A total of nine 8-week-old male C57BL/6 mice weighing (25.0±1.3) g were randomly divided into three groups: 60%
Externí odkaz:
https://doaj.org/article/2839596aa60449c3a2e5d410189dc007
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 43, Iss 5, Pp 504-511 (2023)
As the incidence of male infertility has been increasing during recent years, it is urgent to reveal the pathogenesis of male infertility, as well as to develop the new drugs for treatment of male infertility, in order to solve the declining birth ra
Externí odkaz:
https://doaj.org/article/4eb33b1da5cc4411add22b3e000814d7
Autor:
CHEN Yanjuan, SHEN Ruling
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 43, Iss 5, Pp 512-523 (2023)
Colorectal cancer (CRC) is the third most common malignant tumor in the world. The latest statistics show that CRC accounts for 10% of all cancer cases worldwide and is the second leading cause of cancer deaths. CRC is a highly heterogeneous disease,
Externí odkaz:
https://doaj.org/article/bb93bbeb4a584cb78e9be737fbccddb3
Publikováno v:
Shiyan dongwu yu bijiao yixue, Vol 42, Iss 1, Pp 31-35 (2022)
ObjectiveTo observe the duration of anesthesia in C57BL/6J mice anesthetized using different doses of Zoletil combined with serazine hydrochloride to provide an effective reference for all types of mouse surgery and related experimental design.Method
Externí odkaz:
https://doaj.org/article/3217e345388649158637778a8650c00f
Autor:
Zhao, Huan, Liu, Zixin, Chen, Hui, Han, Maoying, Zhang, Mingjun, Liu, Kuo, Jin, Hengwei, Liu, Xiuxiu, Shi, Mengyang, Pu, Wenjuan, Werner, Markus, Meister, Michael, Kauschke, Stefan G., Sun, Ruilin, Wang, Jinjin, Shen, Ruling, Wang, Qing-Dong, Ma, Xin, Tchorz, Jan S., Zhou, Bin
Publikováno v:
In Cell 12 December 2024 187(25):7314-7334
Autor:
Lu, Yue, Cai, Tiantian, Gao, Juanjuan, Ren, Yangge, Ding, Yi, Liu, Shujing, Liu, Linyuan, Huang, Hao, Wang, Haijie, Wang, Chengji, Wang, Wei, Shen, Ruling, Zhu, Bo, Jia, Lin
Publikováno v:
In Materials Today Bio December 2024 29
Publikováno v:
In European Journal of Pharmaceutical Sciences 1 October 2024 201