Xiao-xu-ming Decoction Improved Synaptic Damage after Acute Cerebral Ischemia and Reperfusion via JAK2/STAT3 Pathway in Rats.

Autor: Lan R; The Department of Encephalopathy, The First Affiliated Hospital of Henan University of Chinese Medicine, Henan 450000, China., Zhang Y; The Department of Traditional Chinese Medicine, The Third Affiliated Hospital of Zhengzhou University, Henan 450000, China., Fu XQ; Henan University of Chinese Medicine, Henan 450000, China., Wang MM; Henan University of Chinese Medicine, Henan 450000, China., Zou XH; Henan University of Chinese Medicine, Henan 450000, China., Wang WW; Henan University of Chinese Medicine, Henan 450000, China., Shen XM; The Department of Encephalopathy, The First Affiliated Hospital of Henan University of Chinese Medicine, Henan 450000, China., Zhang ZQ; The Department of Encephalopathy, The First Affiliated Hospital of Henan University of Chinese Medicine, Henan 450000, China; Henan University of Chinese Medicine, Henan 450000, China. Electronic address: zhang_zhenqiang@126.com.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2024 Dec 16, pp. 119261. Date of Electronic Publication: 2024 Dec 16.

A rare complex structural variant of novel intragenic inversion combined with reciprocal translocation t(X;1)(p21.2;p13.3) in Duchenne muscular dystrophy.

Autor: Wang Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Wen X; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Shen XM; Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic, Rochester, MN 55905, USA., Di L; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Sun Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Li Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Zhang S; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Wen Q; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Wang J; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Duo J; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Huang Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Lu Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Xu M; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Wang M; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Chen H; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Zhu W; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China., Da Y; Department of Neurology, Xuanwu Hospital, Capital Medical University, No. 45 Changchun Street, Xicheng District, Beijing 100053, China. Electronic address: dayuwei100@hotmail.com.

Publikováno v: Neuromuscular disorders : NMD [Neuromuscul Disord] 2024 Jun; Vol. 39, pp. 24-29. Date of Electronic Publication: 2024 Apr 12.

TLR4 inhibition ameliorated glucolipotoxicity-induced differentiation suppression in osteoblasts via RIAM regulation of NF-κB nuclear translocation

Autor: Shen Xm, Li Cc, Lan C, Lin Yf, Cheng L, Zhang Yz, Yan Sj

Publikováno v: Molecular and cellular endocrinology. 543

TLR4 is a key innate immune signal that mediates glucolipid toxicity through yet unclear mechanisms. Here, TLR4 truncation ameliorated bone metabolism disorders in diabetic rats, and the underlying mechanisms were explored by proteomics. Our study sh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e19adc68a99870258ae4fa5afc96fb
https://pubmed.ncbi.nlm.nih.gov/34929310

Impaired gating of γ- and ε-AChR respectively causes Escobar syndrome and fast-channel myasthenia.

Autor: Shen XM; Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic, Rochester, Minnesota, USA., Nakata T; Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Pediatrics, Nagoya University Graduate School of Medicine, Nagoya, Japan., Mizuno S; Department of Pediatrics, Central Hospital, Aichi Human Service Center, Kasugai, Japan., Imoto I; Aichi Cancer Center Research Institute, Nagoya, Japan., Selcen D; Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic, Rochester, Minnesota, USA., Ohno K; Division of Neurogenetics, Center for Neurological Diseases and Cancer, Nagoya University Graduate School of Medicine, Nagoya, Japan., Engel AG; Department of Neurology and Neuromuscular Research Laboratory, Mayo Clinic, Rochester, Minnesota, USA.

Publikováno v: Annals of clinical and translational neurology [Ann Clin Transl Neurol] 2023 May; Vol. 10 (5), pp. 732-743. Date of Electronic Publication: 2023 Mar 09.

Diselenide-Based Dual-Responsive Prodrug as Pyroptosis Inducer Potentiates Cancer Immunotherapy.

Autor: Wan SC; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Ye MJ; School of Materials and Energy and Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing, 400715, P. R. China., Yang QC; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Zhang T; School of Materials and Energy and Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing, 400715, P. R. China., Zhang MJ; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Ma XB; School of Materials and Energy and Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing, 400715, P. R. China., Xu JM; School of Materials and Energy and Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing, 400715, P. R. China., Wang S; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Wu ZZ; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Yang LL; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Shen XM; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China., Xu Z; School of Materials and Energy and Chongqing Engineering Research Center for Micro-Nano Biomedical Materials and Devices, Southwest University, Chongqing, 400715, P. R. China., Sun ZJ; The State Key Laboratory Breeding Base of Basic Science of Stomatology (Hubei-MOST) & Key Laboratory of Oral Biomedicine Ministry of Education, School & Hospital of Stomatology, Wuhan University, Wuhan, 430079, China.

Publikováno v: Advanced healthcare materials [Adv Healthc Mater] 2023 Mar; Vol. 12 (7), pp. e2202135. Date of Electronic Publication: 2022 Dec 11.