Výsledky vyhledávání - "Shelton M. Charles"

Pregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms

Autor: Heather L. Mertz, Shelton M. Charles, Delrae M. Eckman, Lorna G. Moore, Charles R. Rosenfeld, Ridhima Gupta, Timothy M. Morgan

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 303:R368-R375

Myogenic tone (MT) is a primary modulator of blood flow in the resistance vasculature of the brain, kidney, skeletal muscle, and perhaps in other high-flow organs such as the pregnant uterus. MT is known to be regulated by endothelium-derived factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5103d4a8c6965da39942b02ba315a6cc
https://doi.org/10.1152/ajpregu.00490.2011

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Roles of cytosolic Ca2+concentration and myofilament Ca2+sensitization in age-dependent cerebrovascular myogenic tone

Autor: William J. Pearce, Lubo Zhang, John N. Buchholz, Shelton M. Charles, Marilyn J. Cipolla

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology. 299:H1034-H1044

In light of evidence that immature arteries contain a higher proportion of noncontractile smooth muscle cells than found in fully differentiated mature arteries, the present study explored the hypothesis that age-related differences in the smooth mus

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a5cf02892ea552795adda3089882f2d
https://doi.org/10.1152/ajpheart.00214.2010

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Postnatal maturation attenuates pressure-evoked myogenic tone and stretch-induced increases in Ca2+in rat cerebral arteries

Autor: John N. Buchholz, William J. Pearce, Lubo Zhang, Lawrence D. Longo, Shelton M. Charles

Publikováno v: American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 293:R737-R744

Although postnatal maturation potently modulates agonist-induced cerebrovascular contractility, its effects on the mechanisms mediating cerebrovascular myogenic tone remain poorly understood. Because the regulation of calcium influx and myofilament c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1046f8ce8b8775d07fac861115881c2
https://doi.org/10.1152/ajpregu.00869.2006

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Effect of radiation and repeated sub-culturing on the transforming growth factor-β1 signaling pathway in FRTL-5 cells

Autor: Cheryl G, Burrell, Daila S, Gridley, Leticia S, Ortloff, Shelton M, Charles, Lora M, Green

Publikováno v: In vivo (Athens, Greece). 29(1)

Fisher rat thyroid cells (FRTL-5) display increased proliferation, reduced follicularization and decreased thyroxin release with repeated sub-culturing. These changes occur earlier and more rapidly following exposure to ionizing radiation. We hypothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3ab052a8025a99bb3a1f99eee765d76c
https://pubmed.ncbi.nlm.nih.gov/25600523

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Higher Estrogen Levels During Pregnancy in Andean Than European Residents of High Altitude Suggest Differences in Aromatase Activity

Autor: Colleen G. Julian, Lorna G. Moore, Enrique Vargas, Shelton M. Charles

Context: Uteroplacental hypoxia has been reported to lower estrogen levels in preeclampsia as the result of reduced aromatase activity. Objective: We asked whether the chronic hypoxia of residence at high altitude in the absence of preeclampsia lower

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d314eb86c49a3991fdca14645a57e70
https://europepmc.org/articles/PMC4121036/

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Diabetes and adverse mental health among African Americans

Autor: David L, Mount, Kristen G, Hairston, Shelton M, Charles

Publikováno v: North Carolina medical journal. 72(5)

This article reviews the connection between diabetes and adverse mental health among African Americans. Concern about safe insulin prescribing and administration is raised, and the importance of integrated physical and mental health care in the preve

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1bf598ed7021c68ea7425d25e4695df5
https://pubmed.ncbi.nlm.nih.gov/22416525

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Humans at high altitude: hypoxia and fetal growth

Autor: Lorna G. Moore, Colleen G. Julian, Shelton M. Charles

High-altitude studies offer insight into the evolutionary processes and physiological mechanisms affecting the early phases of the human lifespan. Chronic hypoxia slows fetal growth and reduces the pregnancy-associated rise in uterine artery (UA) blo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f023542082b88f6d73320c79803d7746
https://europepmc.org/articles/PMC3146554/

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Capsaicin Pre-treatment Provides Neurovascular Protection Against Neonatal Hypoxic-Ischemic Brain Injury in Rats

Autor: John H. Zhang, Jeffrey Chiu, Nikan H. Khatibi, Shelton M. Charles, Vikram Jadhav, John N. Buchholz, Jiping Tang

Publikováno v: Intracerebral Hemorrhage Research ISBN: 9783709106921

Capsaicin, a transient receptor potential vanilloid 1 (TRPV1) agonist, has recently been shown to provide neuroprotection against brain injury in experimental adult models of cerebral ischemia. Accordingly, in this study, we investigated the way in w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4188bc59168655fd72a32c993d58042e
https://doi.org/10.1007/978-3-7091-0693-8_38

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