Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shelly Zaffryar‐Eilot"'
Autor:
Shay Melamed, Shelly Zaffryar-Eilot, Elisabeth Nadjar-Boger, Rohtem Aviram, Huaning Zhao, Wesal Yaseen-Badarne, Rotem Kalev-Altman, Dalit Sela-Donenfeld, Oded Lewinson, Sophie Astrof, Peleg Hasson, Haguy Wolfenson
Publikováno v:
Cell Reports, Vol 42, Iss 5, Pp 112473- (2023)
Summary: Fibronectin fibrillogenesis and mechanosensing both depend on integrin-mediated force transmission to the extracellular matrix. However, force transmission is in itself dependent on fibrillogenesis, and fibronectin fibrils are found in soft
Externí odkaz:
https://doaj.org/article/fffb9389b51746b59ad9414ad8f3f4e2
Autor:
Wesal Yaseen, Ortal Kraft-Sheleg, Shelly Zaffryar-Eilot, Shay Melamed, Chengyi Sun, Douglas P. Millay, Peleg Hasson
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Classically, myogenic precursor cells derive from somites, and connective tissues derive from lateral plate mesoderm (LPM). Here the authors identify LPM derived fibroblasts that turn on a myogenic program and fuse to muscle fibers at muscle-tendon j
Externí odkaz:
https://doaj.org/article/e0a89d8052694add8716e21454d9a0e1
Autor:
Shelly Zaffryar-Eilot, Peleg Hasson
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 19, p 11378 (2022)
Lysyl oxidases have long been considered key secreted extracellular matrix modifying enzymes. As such, their activity has been associated with the crosslinking of collagens and elastin, and as a result, they have been linked to multiple developmental
Externí odkaz:
https://doaj.org/article/0d544589e816463babfee050566cc5e2
Autor:
Chen Rachman-Tzemah, Shelly Zaffryar-Eilot, Moran Grossman, Dario Ribero, Michael Timaner, Joni M. Mäki, Johanna Myllyharju, Francesco Bertolini, Dov Hershkovitz, Irit Sagi, Peleg Hasson, Yuval Shaked
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 774-784 (2017)
Surgery remains the most successful curative treatment for cancer. However, some patients with early-stage disease who undergo surgery eventually succumb to distant metastasis. Here, we show that in response to surgery, the lungs become more vulnerab
Externí odkaz:
https://doaj.org/article/2686e8bc65004844a77588d2f1547c24
Autor:
Shay Melamed, Shelly Zaffryar-Eilot, Elisabeth Nadjar-Boger, Rohtem Aviram, Huaning Zhao, Wesal Yaseen-Badarne, Rotem Kalev-Altman, Dalit Sela-Donenfeld, Oded Lewinson, Sophie Astrof, Peleg Hasson, Haguy Wolfenson
SummaryFibronectin fibrillogenesis and mechanosensing both depend on integrin-mediated force transmission to the extracellular-matrix. However, force transmission is in itself dependent on fibrillogenesis, and fibronectin fibrils are found in soft em
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a16aa6d5edc3fe2189d9830dceb3bb2
https://doi.org/10.1101/2022.11.16.516843
https://doi.org/10.1101/2022.11.16.516843
Autor:
Chengyi Sun, Shay Melamed, Wesal Yaseen-Badarneh, Peleg Hasson, Shelly Zaffryar-Eilot, Douglas P. Millay, Ortal Kraft-Sheleg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-10 (2021)
Nature Communications
Nature Communications
Vertebrate muscles and tendons are derived from distinct embryonic origins yet they must interact in order to facilitate muscle contraction and body movements. How robust muscle tendon junctions (MTJs) form to be able to withstand contraction forces
Autor:
Hagar Grunwald, Kristina L. Hunker, Isabelle Birt, Chen Lulu, Rohtem Aviram, Shelly Zaffryar‐Eilot, Santhi K. Ganesh, Peleg Hasson
Publikováno v:
The FASEB Journal. 35
Crosstalk between multiple components underlies the formation of mature vessels. Although the players involved in angiogenesis have been identified, mechanisms underlying the crosstalk between them are still unclear. Using the ex vivo aortic ring ass
Autor:
Moran Grossman, Dario Ribero, Michael Timaner, Francesco Bertolini, Dov Hershkovitz, Irit Sagi, Johanna Myllyharju, Peleg Hasson, Yuval Shaked, Joni M. Mäki, Shelly Zaffryar-Eilot, Chen Rachman-Tzemah
Publikováno v:
Cell Reports, Vol 19, Iss 4, Pp 774-784 (2017)
Cell Reports
Cell Reports
Summary Surgery remains the most successful curative treatment for cancer. However, some patients with early-stage disease who undergo surgery eventually succumb to distant metastasis. Here, we show that in response to surgery, the lungs become more
Autor:
Ido Livneh, Peleg Hasson, Ravit Gabay Yehezkely, Anna Kaganovsky, Nurit Fainshtain Malka, Rohtem Aviram, Shelly Zaffryar-Eilot
Publikováno v:
Developmental cell. 53(4)
Integration of extracellular matrix (ECM)-derived cues into transcriptional programs is essential primarily in rapidly morphing environments, such as regenerating tissues. Here, we demonstrate that lysyl oxidase (Lox), known for its ECM-modifying act
Autor:
Ofra Kessler, Ortal Kraft-Sheleg, Tatyana Smolkin, Yuval Cinnamon, Gera Neufeld, Shelly Zaffryar-Eilot, Peleg Hasson, Gal Akiri, Olga Genin, Wesal Yaseen, Sharon Soueid-Baumgarten
Publikováno v:
Developmental Cell. 36:550-561
For muscles to function, myofibers have to stretch and anchor at the myotendinous junction (MTJ), a region rich in extracellular matrix (ECM). Integrin signaling is required for MTJ formation, and mutations affecting the cascade lead to muscular dyst