Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Shelly Yishay"'
Autor:
Shelly Yishay, Leonid Gaidukov, Michal Lindenbaum, Peter Bel, Gabriel Amitai, Guy Yacov, Dan S. Tawfik, Shai Teitlboim, R. Adani, Moshe Kushnir, Haim Meshulam, Olga Khersonsky
Publikováno v:
FEBS Journal. 273:1906-1919
We addressed the ability of various organophosphorus (OP) hydrolases to catalytically scavenge toxic OP nerve agents. Mammalian paraoxonase (PON1) was found to be more active than Pseudomonas diminuta OP hydrolase (OPH) and squid O,O-di-isopropyl flu
Autor:
O. Limanovich, Shai Teitlboim, Gabriel Amitai, Shelly Yishay, R. Adani, Lily Raveh, Liat Tveria, Guy Yacov, Haim Meshulam
Publikováno v:
Chemico-biological interactions. 175(1-3)
Organophosphorus hydrolases (OPH) such as mammalian plama paraoxonase (PON1) detoxify asymmetric toxic organophosphorus (OP) nerve agents by preferentially hydrolyzing the less toxic P(+) optical isomer. In order to develop new OPHs with broader ster
Autor:
Liat Tveria, Haim Meshulam, Shelly Yishay, Gabi Amitai, R. Adani, Moshe Kushnir, Osnat Limanovich, Shai Teitlboim, Guy Yacov
Publikováno v:
Toxicology. 233(1-3)
In order to enhance the enzymatic detoxification rate of organophosphorus (OP) nerve agents we have searched for more active variants of recombinant mammalian paraoxonase (PON1). We have previously identified three key positions in PON1 that affect O
Autor:
Gabriel, Amitai, Leonid, Gaidukov, Rellie, Adani, Shelly, Yishay, Guy, Yacov, Moshe, Kushnir, Shai, Teitlboim, Michal, Lindenbaum, Peter, Bel, Olga, Khersonsky, Dan S, Tawfik, Haim, Meshulam
Publikováno v:
The FEBS journal. 273(9)
We addressed the ability of various organophosphorus (OP) hydrolases to catalytically scavenge toxic OP nerve agents. Mammalian paraoxonase (PON1) was found to be more active than Pseudomonas diminuta OP hydrolase (OPH) and squid O,O-di-isopropyl flu