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A Case of Methotrexate Neurotoxicity Presented as Status Epilepticus, Encephalopathy, and High Fever
Autor:
Itay Ayalon MD, Shirley Friedman MD, Yoav Binenbaum MD, Noga Oppenheimer MD, Shelly Shiran MD, Galia Grisaru-Soen MD, Shimrit Uliel-Sibony MD, Miguel Glatstein MD, Jennifer Melissa Kaplan MD, MS, Efraim Sadot MD
Publikováno v:
Journal of Investigative Medicine High Impact Case Reports, Vol 7 (2019)
High-dose methotrexate is used to treat a range of adult and childhood cancers including osteosarcoma. Significant neurotoxicity is reported in 1% to 4.5% of patients treated with high-dose methotrexate and can present in a wide variety of symptoms.
Externí odkaz:
https://doaj.org/article/64b27e7aa5d54d60983e6b1069711110