Výsledky vyhledávání - "Shelly Harel"

Akademický článek

ONX 0914 Lacks Selectivity for the Cardiac Immunoproteasome in CoxsackievirusB3 Myocarditis of NMRI Mice and Promotes Virus-Mediated Tissue Damage

Autor: Hannah Louise Neumaier, Shelly Harel, Karin Klingel, Ziya Kaya, Arnd Heuser, Meike Kespohl, Antje Beling

Publikováno v: Cells, Vol 9, Iss 5, p 1093 (2020)

Inhibition of proteasome function by small molecules is highly efficacious in cancer treatment. Other than non-selective proteasome inhibitors, immunoproteasome-specific inhibitors allow for specific targeting of the proteasome in immune cells and th

Externí odkaz: https://doaj.org/article/c2891531edc74ebe8d9979c4098a2815

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When less is more – Endogenous tagging with TurboID as a tool to study the native interactome of adaptor protein complexes

Autor: Alexander Stockhammer, Laila S. Benz, Shelly Harel, Vini Natalia, Lukas Wiench, Christian Freund, Benno Kuropka, Francesca Bottanelli

In recent years, proximity labelling has established itself as an unbiased and powerful approach to map the interactome of specific proteins. Generally, protein fusions with labelling enzymes are transiently overexpressed to perform these experiments

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::68abb89fc005bb5cd65140a59c2962f6
https://doi.org/10.1101/2021.11.19.469212

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Role of NF-kB RelB in Aryl Hydrocarbon Receptor-Mediated Ligand Specific Effects

Autor: Shelly Harel, Yasuhiro Ishihara, Sarah Y. Kado, Christiane Hoeper, Christoph F.A. Vogel

Publikováno v: International journal of molecular sciences, vol 20, iss 11
International Journal of Molecular Sciences, Vol 20, Iss 11, p 2652 (2019)
International Journal of Molecular Sciences

Here, we investigate the role of RelB in the regulation of genes which were identified to be induced in an aryl hydrocarbon receptor (AhR)-dependent manner and critically involved in regulation of immune responses. We analyzed the expression of genes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db602834f8b6f0216f387eb3481c9ded
http://ir.lib.hiroshima-u.ac.jp/00048679

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