Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Shelly A. Glase"'
Autor:
David Juergen Wustrow, Thomas G. Heffner, Michael Duff Davis, Lynn M. Georgic, Suzanne Ross Kesten, Anthony C. Blackburn, Ronald Rubin, Thomas Richard Belliotti, Shelly Ann Glase, Ann E. Corbin, Hyacinth Akunne, T. A. Pugsley, Norman L. Colbry, Steven Z. Whetzel, Kim Zoski, Lawrence D. Wise, D. R. Johnson
Publikováno v:
Journal of Medicinal Chemistry. 41:760-771
A series of [4-[2(4-arylpiperazin-1-yl)alkyl]cyclohexyl]pyrimidin-2-ylamine s was prepared and found to have receptor binding affinity for D2 and D3 dopamine (DA) receptors and serotonin 5-HT1A receptors. The structural contributions to D2/D3 and 5-H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a87db13947cb7fb22fb6f9cfb72e85f
https://doi.org/10.1021/jm9707378
https://doi.org/10.1021/jm9707378
Autor:
Jonas Nilsson, Sergio Clementi, Manuel Pastor, Shelly Ann Glase, Age K. Smilde, Tom Pugsley, Gabriele Cruciani, Håkan Wikström
Publikováno v:
Journal of Medicinal Chemistry, 6, 833-840. AMER CHEMICAL SOC
Journal of medicinal chemistry, 40(6), 833-840. American Chemical Society
Journal of medicinal chemistry, 40(6), 833-840. American Chemical Society
In the search for drugs against schizophrenia and depression without extrapyramidal side effects, compounds that selectively antagonize the dopamine D3 receptor subtype are thought to be a solution. In order to create a model with which the D3 activi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b420d163ff240a3b9af03e7459f30c
https://doi.org/10.1021/jm9605952
https://doi.org/10.1021/jm9605952
Autor:
Stephen Joseph Johnson, Shelly A. Glase, Suzanne R. Kesten, Peter J. Manley, Lawrence D. Wise, Jon Wright, Thomas G. Heffner, Thomas A. Pugsley, Robert G. MacKenzie, Hyacinth C. Akunne
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:1361-1366
A series of 4-bromo-1-methoxy-N-[2-(4-aryl-1-piperazinyl)ethyl]-2-naphthalenecarboxamide dopamine (DA) D 3 receptor agonists has been identified. These compounds were found to be selective for DA D 3 over D 2 receptors and were shown to be partial to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b944dbffb56fd0b3f3b76b3ac650a3a3
https://doi.org/10.1016/0960-894x(96)00231-4
https://doi.org/10.1016/0960-894x(96)00231-4
Publikováno v:
Journal of Medicinal Chemistry. 38:3132-3137
The pyridine analogs of 5-hydroxy-2-(di-n-propylamino)tetralin (5-OH-DPAT), 4-6, were synthesized, and their biological activity was compared to that of 5-OH-DPAT. Compounds 4 and 6 exhibited activity similar to 5-OH-DPAT in dopamine (DA) D2 and D3 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25111a5975f3cf45f7f89d782a1993a3
https://doi.org/10.1021/jm00016a016
https://doi.org/10.1021/jm00016a016
Publikováno v:
ChemInform. 26
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53933750cd963e35639680f55a2142e7
https://doi.org/10.1002/chin.199551176
https://doi.org/10.1002/chin.199551176
Autor:
Robert G. MacKenzie, Thomas A. Pugsley, Thomas G. Heffner, Juan C. Jaen, Lawrence D. Wise, Sarah Jane Smith, Hyacinth C. Akunne, Shelly A. Glase, Leonard T. Meltzer
Publikováno v:
ChemInform. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40eb649b60fb9c70e4572df2a7eb275f
https://doi.org/10.1002/chin.199648147
https://doi.org/10.1002/chin.199648147
Publikováno v:
ChemInform. 40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e6a604139fd213ab26558f6a3228ff3
https://doi.org/10.1002/chin.200909164
https://doi.org/10.1002/chin.200909164
Publikováno v:
Bioorganicmedicinal chemistry letters. 18(20)
As part of a discovery effort aimed at identifying novel norepinephrine reuptake inhibitors (NRIs), a number of substituted morpholines were designed and synthesized. The target compounds contain vicinal stereogenic centers, and the program was great
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d4d1323cdf376fa3b4907974ebf5169
https://pubmed.ncbi.nlm.nih.gov/18805691
https://pubmed.ncbi.nlm.nih.gov/18805691
Autor:
Shelly Ann Glase, David J. Dooley
Publikováno v:
Annual Reports in Medicinal Chemistry ISBN: 9780120405398
Publisher Summary This chapter presents new therapeutic approaches for the treatment attention-deficit/hyperactivity disorder (ADHD) such as monoamine reuptake inhibitors, Dopamine D 4 antagonists, α 2 -Adrenergic agonists, histamine H 3 antagonists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de89b3352400328183d85337086be0ed
https://doi.org/10.1016/s0065-7743(04)39001-9
https://doi.org/10.1016/s0065-7743(04)39001-9
