Zobrazeno 1 - 10
of 163
pro vyhledávání: '"Shelly, Heimfeld"'
Autor:
Curt I. Civin, Jeanne Kowalski, Greg Riggins, Francisco Martinez-Murillo, Laura Carr, Chen Chen, Shelly Heimfeld, Matthew Malehorn, Vivek Tanadve, Robert W. Georgantas
The human CD34+/CD38−/Lin− cell subset, comprising ∼1–10% of the CD34+ cell population, contains few of the less primitive hematopoietic (lineage-committed) progenitor cells (HPCs) but most of the primitive in vivo engrafting (lympho-)hematop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c6e7f0dbabcb33b62a622de9d94426
https://doi.org/10.1158/0008-5472.c.6493971.v1
https://doi.org/10.1158/0008-5472.c.6493971.v1
Autor:
Curt I. Civin, Jeanne Kowalski, Greg Riggins, Francisco Martinez-Murillo, Laura Carr, Chen Chen, Shelly Heimfeld, Matthew Malehorn, Vivek Tanadve, Robert W. Georgantas
http://tagmapper.ibioinformatics.org/HSC/final_report.htm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be24a799ac3521b0efb09ad4f842251
https://doi.org/10.1158/0008-5472.22363983
https://doi.org/10.1158/0008-5472.22363983
Autor:
Curt I. Civin, Jeanne Kowalski, Greg Riggins, Francisco Martinez-Murillo, Laura Carr, Chen Chen, Shelly Heimfeld, Matthew Malehorn, Vivek Tanadve, Robert W. Georgantas
Supplementary Figures from Microarray and Serial Analysis of Gene Expression Analyses Identify Known and Novel Transcripts Overexpressed in Hematopoietic Stem Cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83bf2a379801961d144f085efd386e4c
https://doi.org/10.1158/0008-5472.22363986.v1
https://doi.org/10.1158/0008-5472.22363986.v1
Autor:
Jennifer E. Adair, Timothy Waters, Kevin G. Haworth, Sara P. Kubek, Grant D. Trobridge, Jonah D. Hocum, Shelly Heimfeld, Hans-Peter Kiem
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Current methods for haematopoietic stem cell gene therapy are laborious and require special licensed facilities. Here the authors develop a semi-automated protocol using a commercially available device to allow for benchtop generation of gene-modifie
Externí odkaz:
https://doaj.org/article/583cfd673dbc436f8e0a56f2549b1b65
Autor:
Marie Bleakley, Alison Sehgal, Stuart Seropian, Melinda A. Biernacki, Elizabeth F. Krakow, Ann Dahlberg, Heather Persinger, Barbara Hilzinger, Paul J. Martin, Paul A. Carpenter, Mary E. Flowers, Jenna Voutsinas, Theodore A. Gooley, Keith Loeb, Brent L. Wood, Shelly Heimfeld, Stanley R. Riddell, Warren D. Shlomchik
Publikováno v:
J Clin Oncol
PURPOSE Graft-versus-host disease (GVHD) causes morbidity and mortality following allogeneic hematopoietic cell transplantation. Naive T cells (TN) cause severe GVHD in murine models. We evaluated chronic GVHD (cGVHD) and other outcomes in three phas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6817d1901eb3d9a3cfc38e9e7430844b
https://europepmc.org/articles/PMC8987226/
https://europepmc.org/articles/PMC8987226/
Autor:
Fang Sun, Suzan Imren, Bowen Li, Fabiola Merriam, Cynthia Nourigat, Shelly Heimfeld, Peng Zhang, Priyesh Jain, Andrew Sinclair, Jianqiang Li, Colleen Delaney, Ryan Basom, Tao Bai, Hsiang-Chieh Hung, Jeffrey J. Delrow, Mary Beth O'Kelly, Shaoyi Jiang
Publikováno v:
Nature Medicine. 25:1566-1575
The ability to expand hematopoietic stem and progenitor cells (HSPCs) ex vivo is critical to fully realize the potential of HSPC-based therapies. In particular, the application of clinically effective therapies, such as cord blood transplantation, ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61aa60737939fcb6da8e3e867a5467b2
https://doi.org/10.1038/s41591-019-0601-5
https://doi.org/10.1038/s41591-019-0601-5
Autor:
Kara A Scheibner, Brianne Teaboldt, Mary Claire Hauer, Xiaochun Chen, Srujana Cherukuri, Yin Guo, Shannon M Kelley, Zhenqiu Liu, Maria R Baer, Shelly Heimfeld, Curt I Civin
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e50895 (2012)
MicroRNAs (miRs) play major roles in normal hematopoietic differentiation and hematopoietic malignancies. In this work, we report that miR-27a, and its coordinately expressed cluster (miR-23a∼miR-27a∼miR-24-2), was down-regulated in acute leukemi
Externí odkaz:
https://doaj.org/article/f3f653cf4b9b49d29412744869333db9
Autor:
Dong Hoon Lee, Michael C. Jensen, Damian J. Green, Lihua E. Budde, Oliver W. Press, Shelly Heimfeld, Philip Olsen, Sang Yun Lee, Shyril O'Steen, Brian G. Till, Stanley R. Riddell, Aimee L. Kenoyer
Publikováno v:
Journal of Immunotherapy. 41:19-31
Chimeric antigen receptor (CAR) based adoptive T cell therapy is a highly promising treatment for lymphoid malignancies, and CD20 is an ideal target antigen. We previously developed a lentiviral construct encoding a 3rd generation CD20-targeted CAR b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1e8997810fc0c5222d9d827f796905f
https://doi.org/10.1097/cji.0000000000000199
https://doi.org/10.1097/cji.0000000000000199
Autor:
Keith M. Sullivan, Linda M. Griffith, Kaitlyn C. Steinmiller, Shelly Heimfeld, Tomeka C. Granderson, Christine W. Czarniecki, Julia S. Goldstein, Richard A. Nash, Carolyn A. Keever-Taylor
Publikováno v:
Biology of Blood and Marrow Transplantation. 23:1463-1472
To ensure comparable grafts for autologous hematopoietic cell transplantation (HCT) in the National Institute of Allergy and Infectious Diseases–sponsored Investigational New Drug protocols for multiple sclerosis (HALT-MS) and systemic sclerosis (S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a3b45c7a71367cf080190e325a7fffe
https://doi.org/10.1016/j.bbmt.2017.05.018
https://doi.org/10.1016/j.bbmt.2017.05.018
Autor:
Ian B. Nicoud, Suzan Imren, Joseph Blake, Jianqiang Li, Shelly Heimfeld, Colleen Delaney, Filippo Milano, Emily Cox, David C. Oliver
Publikováno v:
Biology of Blood and Marrow Transplantation. 23:412-419
Cord blood transplantation (CBT) recipients are at increased risk for delayed engraftment and primary graft failure, complications that are often indistinguishable early post-transplantation. Current assays fail to accurately identify recipients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7885b025484272d11d16f9ac37446fa1
https://doi.org/10.1016/j.bbmt.2016.12.625
https://doi.org/10.1016/j.bbmt.2016.12.625