Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Shelli M. Homan"'
Publikováno v:
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)
Abstract Background Heart disease (HD) is the major cause of morbidity and mortality in patients with hypereosinophilic diseases. Due to a lack of adequate animal models, our understanding of the pathophysiology of eosinophil-mediated diseases with h
Externí odkaz:
https://doaj.org/article/9cf599db28da4f96af20383776ebf485
Autor:
Xinjian Wang, Matthias Eckenweiler, Peter Hedera, Michael Zech, Juliane Winkelmann, Donald L. Gilbert, Derek E. Neilson, Shelli M. Homan, Jesse Slone, Nancy D. Leslie, Brian Gebelein, Lisa M. Gutzwiller, Jianfeng Xiao, Taosheng Huang, Robert B. Hufnagel, Elizabeth J. Leslie, Mark S. LeDoux, Friederike Wilbert
Publikováno v:
Mov Disord
BACKGROUND In a large pedigree with an unusual phenotype of spastic paraplegia or dystonia and autosomal dominant inheritance, linkage analysis previously mapped the disease to chromosome 2q24-2q31. OBJECTIVE The aim of this study is to identify the
Publikováno v:
BMC Genomics
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)
BMC Genomics, Vol 20, Iss 1, Pp 1-15 (2019)
BackgroundHeart disease (HD) is the major cause of morbidity and mortality in patients with hypereosinophilic diseases. Due to a lack of adequate animal models, our understanding of the pathophysiology of eosinophil-mediated diseases with heart compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdc0a0b7a01a1970c59a192ce37d69c4
https://doi.org/10.21203/rs.2.11533/v1
https://doi.org/10.21203/rs.2.11533/v1
BackgroundHeart disease (HD) is the major cause of morbidity and mortality in patients with hypereosinophilic diseases. Due to a lack of adequate animal models, our understanding of the pathophysiology of eosinophil-mediated diseases with heart compl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ca2d376c2343f95b3dacfb89e533e27
Publikováno v:
Am J Physiol Heart Circ Physiol
Hypereosinophilic syndrome is characterized by sustained and marked eosinophilia leading to tissue damage and organ dysfunction. Morbidity and mortality occur primarily due to cardiac and thromboembolic complications. Understanding the cause and mech
Publikováno v:
Blood. 132:3686-3686
Introduction: Hypereosinophilic syndrome is characterized by sustained blood and/or tissue hypereosinophilia leading to tissue damage and organ dysfunction. Nearly half the cases are classified as idiopathic, since no known cause is identified and th