Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Shelli M Morris"'
Autor:
Yanxin Luo, Andrew M Kaz, Samornmas Kanngurn, Piri Welsch, Shelli M Morris, Jianping Wang, James D Lutterbaugh, Sanford D Markowitz, William M Grady
Publikováno v:
PLoS Genetics, Vol 9, Iss 7, p e1003552 (2013)
NTRK3 is a member of the neurotrophin receptor family and regulates cell survival. It appears to be a dependence receptor, and thus has the potential to act as an oncogene or as a tumor suppressor gene. NTRK3 is a receptor for NT-3 and when bound to
Externí odkaz:
https://doaj.org/article/b0e3aaf7df6f4288b736c8dc7a308ba5
Autor:
Quy Le, Brandon Hadland, Jenny L. Smith, Amanda Leonti, Benjamin J. Huang, Rhonda Ries, Tiffany A. Hylkema, Sommer Castro, Thao T. Tang, Cyd N. McKay, LaKeisha Perkins, Laura Pardo, Jay Sarthy, Amy K. Beckman, Robin Williams, Rhonda Idemmili, Scott Furlan, Takashi Ishida, Lindsey Call, Shivani Srivastava, Anisha M. Loeb, Filippo Milano, Suzan Imren, Shelli M. Morris, Fiona Pakiam, Jim M. Olson, Michael R. Loken, Lisa Brodersen, Stanley R. Riddell, Katherine Tarlock, Irwin D. Bernstein, Keith R. Loeb, Soheil Meshinchi
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
The CBFA2T3-GLIS2 (C/G) fusion is a product of a cryptic translocation primarily seen in infants and early childhood and is associated with dismal outcome. Here, we demonstrate that the expression of the C/G oncogenic fusion protein promotes the tran
Externí odkaz:
https://doaj.org/article/134ccd270d5242848fcfcd4f706249e4
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Background: Barrett's esophagus (BE) is a preneoplastic condition in which normal esophageal squamous epithelium (SQ) is replaced by specialized intestinal metaplasia. It is the presumed precursor for esophageal adenocarcinoma (EAC) as well as the st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941857518300e5f67042f08db413d9f4
https://doi.org/10.1158/1055-9965.c.6515770.v1
https://doi.org/10.1158/1055-9965.c.6515770.v1
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Figure S1: Assessment of precision of pyrosequencing assay for methylated B3GAT2 and ZNF793. Supplemental Figure S2: Correlation of pyrosequencing results with HM450 array beta values.Supplemental Figure S3: Methylation status of B3GAT2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e4d95f1274e095f79e0bb852c8f8a50
https://doi.org/10.1158/1055-9965.22437193
https://doi.org/10.1158/1055-9965.22437193
Autor:
William M. Grady, Jill S. Barnholtz-Sloan, Yanwen Chen, Nicholas J. Shaheen, Chao-Jen Wong, Maria Westerhoff, Sharmila Anandabapasathy, Dean E. Brenner, Sanford D. Markowitz, Helen R. Moinova, Joseph E. Willis, Apoorva Chandar, Amitabh Chak, Kelly T. Carter, Shelli M. Morris, Andrew M. Kaz, Rachele M. O'Leary, Ming Yu
Supplemental Table S2: Methylation levels for B3GAT2 and ZNF793 from Human Methylation450 arrays.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d589175f20dad46f6d562232a6a2c92
https://doi.org/10.1158/1055-9965.22437187
https://doi.org/10.1158/1055-9965.22437187
Autor:
Matt Biery, James M. Olson, Carrie Myers, Fiona Pakiam, Shelli M. Morris, Alyssa Noll, Nicholas A Vitanza, Bonnie Cole, Samuel R. Browd, Conrad A Winter
Publikováno v:
Journal of experimental neurology
Diffuse intrinsic pontine glioma (DIPG) is a universally fatal tumor of the brainstem, most commonly affecting young children. Due to its location, surgical resection is not achievable, but consideration of a biopsy has become standard practice at ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08b4a2f43eab2dd508bb27204bc7b383
http://europepmc.org/articles/PMC7990285
http://europepmc.org/articles/PMC7990285
Autor:
Fiona Pakiam, Sabine Mueller, Matt Biery, Emily J. Girard, Carrie Myers, James M. Olson, Ye Zheng, Javad Nazarian, Alyssa Noll, Bonnie Cole, Mi-Youn Brusniak, Raphael Gottardo, Courtney A. Crane, Giulia Park, Justyna M Przystal, Jay F. Sarthy, Sarah Leary, Andrew J. Mhyre, Nicholas A Vitanza, Conrad A Winter, Nicole A P Lieberman, Eric Ferguson, Shelli M. Morris
Publikováno v:
Neuro Oncol
Background Diffuse midline gliomas (DMGs), including diffuse intrinsic pontine gliomas (DIPGs), have a dismal prognosis, with less than 2% surviving 5 years postdiagnosis. The majority of DIPGs and all DMGs harbor mutations altering the epigenetic re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc262c40d12a00059a654cc1ed5c9fae
https://pubmed.ncbi.nlm.nih.gov/33470409
https://pubmed.ncbi.nlm.nih.gov/33470409
Autor:
Carrie Myers, Muhammed Murtaza, Conrad A Winter, Michael E. Berens, Raphael Gottardo, Matt Biery, Shelli M. Morris, Mi-Youn Brusniak, Ye Zheng, Nicholas Vitanza, Alyssa Noll, Danyelle Paine, Emily J. Girard, Jessica B. Foster, Matthew D. Dun, Andrew J. Mhyre, James M. Olson
Publikováno v:
Neuro Oncol
Diffuse intrinsic pontine glioma (DIPG) continues to carry a dismal prognosis despite a growing understanding of its epigenetic regulation. While generally reclassified as diffuse midline glioma, H3 K27M-mutant (DMG), a subgroup of DIPGs do not harbo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c1a0c0190e4003b48b7a4e8ed61e2f
https://doi.org/10.1093/neuonc/noab196.697
https://doi.org/10.1093/neuonc/noab196.697
Autor:
Eric Ferguson, Shelli M. Morris, Emily J. Girard, Nicholas A Vitanza, Mi-Youn Brusniak, Matt Biery, Bonnie Cole, Carrie Myers, Fiona Pakiam, Andrew J. Mhyre, Giulia Park, Alyssa Noll, James M. Olson
Publikováno v:
Neuro-Oncology
As the majority of diffuse intrinsic pontine glioma (DIPG) have H3K27M mutations, epigenetic-targeting agents have been studied, though evaluations have been limited by their model systems, untranslatable drug concentrations, and/or evasive mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe17aa4827f2730bb66a2884cbb67636
https://doi.org/10.1093/neuonc/noaa222.060
https://doi.org/10.1093/neuonc/noaa222.060
Autor:
Andrew J. Mhyre, James M. Olson, Alyssa Noll, Shelli M. Morris, Erin E. Crotty, Ken Brasel, Emily J. Girard
Publikováno v:
Neuro-Oncology
Systemic interferon-γ (IFNγ) has been shown to induce major histocompatibility complex class I (MHC-I) and T cell infiltration in solid tumors in adult patients, demonstrating a potential strategy to abrogate tumor-intrinsic mechanisms of immune es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b621fccf32e04fca40142a43cd4b147
https://doi.org/10.1093/neuonc/noaa222.601
https://doi.org/10.1093/neuonc/noaa222.601