Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shelley M. MacNeil"'
Autor:
Mumtahena Rahman, Shelley M. MacNeil, David F. Jenkins, Gajendra Shrestha, Sydney R. Wyatt, Jasmine A. McQuerry, Stephen R. Piccolo, Laura M. Heiser, Joe W. Gray, W. Evan Johnson, Andrea H. Bild
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-19 (2017)
Abstract Background The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the
Externí odkaz:
https://doaj.org/article/b3272234b5d5417c9646f7557697b3d6
Autor:
Kaanan P. Shah, Jason Perera, Eric Lefkofsky, Jerod Parsons, Aly Khan, Denise Lau, Catherine Iguartua, Robert Tell, Timothy Taxter, Martin Bontrager, Shelly Sorrells, Kimberly Yeatts, Stephen Bush, Jackson Michuda, Nike Beaubier, Shelley M. MacNeil, Kevin P. White, Alan Chang, Timothy Baker, Brett Mahon, Robert Huether, Philip Ellis
Publikováno v:
Oncotarget
We developed and clinically validated a hybrid capture next generation sequencing assay to detect somatic alterations and microsatellite instability in solid tumors and hematologic malignancies. This targeted oncology assay utilizes tumor-normal matc
Autor:
Stephen R. Piccolo, W. Evan Johnson, Shelley M. MacNeil, Andrea H. Bild, Mumtahena Rahman, David Jenkins, Gajendra Shrestha, Sydney Rose Wyatt, Laura M. Heiser, Joe W. Gray, Jasmine A. McQuerry
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-19 (2017)
Genome Medicine
Genome Medicine
Background The growth factor receptor network (GFRN) plays a significant role in driving key oncogenic processes. However, assessment of global GFRN activity is challenging due to complex crosstalk among GFRN components, or pathways, and the inabilit
Autor:
Andrea H. Bild, Sunil Sharma, Gajendra Shrestha, Shelley M. MacNeil, David Jenkins, Jasmine A. McQuerry
Publikováno v:
Seminars in Cell & Developmental Biology. :108-117
The rise in genomic knowledge over the past decade has revealed the molecular etiology of many diseases, and has identified intricate signaling network activity in human cancers. Genomics provides the opportunity to determine genome structure and cap
Publikováno v:
Genome Medicine
Although in some cases individual genomic aberrations may drive disease development in isolation, a complex interplay among multiple aberrations is common. Accordingly, we developed Gene Set Omic Analysis (GSOA), a bioinformatics tool that can evalua