Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Shelley M. Herbrich"'
Autor:
Michael H. McGuire, Shelley M. Herbrich, Santosh K. Dasari, Sherry Y. Wu, Ying Wang, Rajesha Rupaimoole, Gabriel Lopez-Berestein, Keith A. Baggerly, Anil K. Sood
Publikováno v:
EBioMedicine, Vol 43, Iss , Pp 127-137 (2019)
Background: Investigations into the function of non-promoter DNA methylation have yielded new insights into the epigenetic regulation of gene expression. However, integrated genome-wide non-promoter DNA methylation and gene expression analyses across
Externí odkaz:
https://doaj.org/article/b4067c0beb384d1fb79d6c599e204a48
Autor:
Sankaranarayan Kannan, Mary E. Irwin, Shelley M. Herbrich, Tiewei Cheng, LaNisha L. Patterson, Marisa J. L. Aitken, Kapil Bhalla, M. James You, Marina Konopleva, Patrick A. Zweidler-McKay, Joya Chandra
Publikováno v:
Antioxidants, Vol 11, Iss 4, p 717 (2022)
Acute myeloid leukemia (AML) is a molecularly heterogenous hematological malignancy, with one of the most common mutations being internal tandem duplication (ITD) of the juxtamembrane domain of the fms-like tyrosine kinase receptor-3 (FLT3). Despite
Externí odkaz:
https://doaj.org/article/83896798bb5e4678bb764333446a8a57
Autor:
Sherry Y. Wu, Rajesha Rupaimoole, Fangrong Shen, Sunila Pradeep, Chad V. Pecot, Cristina Ivan, Archana S. Nagaraja, Kshipra M. Gharpure, Elizabeth Pham, Hiroto Hatakeyama, Michael H. McGuire, Monika Haemmerle, Viviana Vidal-Anaya, Courtney Olsen, Cristian Rodriguez-Aguayo, Justyna Filant, Ehsan A. Ehsanipour, Shelley M. Herbrich, Sourindra N. Maiti, Li Huang, Ji Hoon Kim, Xinna Zhang, Hee-Dong Han, Guillermo N. Armaiz-Pena, Elena G. Seviour, Sue Tucker, Min Zhang, Da Yang, Laurence J. N. Cooper, Rouba Ali-Fehmi, Menashe Bar-Eli, Ju-Seog Lee, Prahlad T. Ram, Keith A. Baggerly, Gabriel Lopez-Berestein, Mien-Chie Hung, Anil K. Sood
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The formation of blood vessels in tumours, angiogenesis, is a promising target for therapy. Here, the authors show that microRNA192 has anti-angiogenic functions and negatively regulates EGR1 and HOXB9, and that delivery of this microRNA to tumours i
Externí odkaz:
https://doaj.org/article/eb7d16e04f0748669c65e11456597cc9
Autor:
Padmanee Sharma, Sangeeta Goswami, Deblina Raychaudhuri, Bilal A. Siddiqui, Pratishtha Singh, Ashwat Nagarajan, Jielin Liu, Sumit K. Subudhi, Candice Poon, Kristal L. Gant, Shelley M. Herbrich, Swetha Anandhan, Shajedul Islam, Moran Amit, Gayathri Anandappa, James P. Allison
Publikováno v:
Cell. 186:1652-1669
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::74a54a1234fcccf897fc414ba8a1eb5b
https://doi.org/10.1016/j.cell.2023.03.006
https://doi.org/10.1016/j.cell.2023.03.006
Autor:
Patrick A. Zweidler-McKay, Joya Chandra, Charles G. Mullighan, Marina Konopleva, Guangchun Song, Jared K. Burks, Duncan H. Mak, Mandy G. Hall, Leonard S. Golfman, Shelley M. Herbrich, Marisa J.L. Aitken, Sankaranarayanan Kannan
(A) Representative histograms of Annexin V abundance in Ph-like B-ALL patient samples cultured with pate-bound IgG-Fc and and increasing concentrations of DLL1-Fc after 3 days. (B) mRNA expression of Notch target gene HES1 in T-ALL and B-ALL cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0566aa7777ad997647f911e9db4b48b2
https://doi.org/10.1158/1535-7163.22506076.v1
https://doi.org/10.1158/1535-7163.22506076.v1
Autor:
Patrick A. Zweidler-McKay, Joya Chandra, Charles G. Mullighan, Marina Konopleva, Guangchun Song, Jared K. Burks, Duncan H. Mak, Mandy G. Hall, Leonard S. Golfman, Shelley M. Herbrich, Marisa J.L. Aitken, Sankaranarayanan Kannan
Primary Ph-like B-ALL (Pt.B1) was treated with PLK1 inhibitor volasertib (100 nm) for 30 min. Cells were harvested and subjected to single cell time of flight mass cytometry (CyTOF) and analyzed using the Spanning Tree Progression of Density Normaliz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63600c08cb6c4a06f02db55be876a969
https://doi.org/10.1158/1535-7163.22506073
https://doi.org/10.1158/1535-7163.22506073
Autor:
Patrick A. Zweidler-McKay, Joya Chandra, Charles G. Mullighan, Marina Konopleva, Guangchun Song, Jared K. Burks, Duncan H. Mak, Mandy G. Hall, Leonard S. Golfman, Shelley M. Herbrich, Marisa J.L. Aitken, Sankaranarayanan Kannan
U133A microarray (Affymetrix) gene expression data for 172 B-ALL patients, 34 T-ALL patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8cc9052e56f780766e1d9b7e5bed474
https://doi.org/10.1158/1535-7163.22506070.v1
https://doi.org/10.1158/1535-7163.22506070.v1
Autor:
Patrick A. Zweidler-McKay, Joya Chandra, Charles G. Mullighan, Marina Konopleva, Guangchun Song, Jared K. Burks, Duncan H. Mak, Mandy G. Hall, Leonard S. Golfman, Shelley M. Herbrich, Marisa J.L. Aitken, Sankaranarayanan Kannan
In B-cell acute lymphoblastic leukemia (B-ALL), activation of Notch signaling leads to cell-cycle arrest and apoptosis. We aimed to harness knowledge acquired by understanding a mechanism of Notch-induced cell death to elucidate a therapeutically via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e63d71ece1383a2666e7a1efacdf822d
https://doi.org/10.1158/1535-7163.c.6538282.v1
https://doi.org/10.1158/1535-7163.c.6538282.v1
Autor:
Anil K. Sood, Keith A. Baggerly, Wei Hu, Cristina Ivan, Bulent Ozpolat, Gabriel Lopez-Berestein, Rajesha Rupaimoole, Sherry Y. Wu, Heather J. Dalton, Jamie Guenthoer, Robert L. Coleman, Erin K. Crane, Alpa M. Nick, Anna K. Unruh, Shelley M. Herbrich, Kshipra Gharpure, Susan L. Tucker
Purpose: Residual disease following primary cytoreduction is associated with adverse overall survival in patients with epithelial ovarian cancer. Accurate identification of patients at high risk of residual disease has been elusive, lacking external
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46533f3ff2d0b09961ba4518cdc7a35b
https://doi.org/10.1158/1078-0432.c.6523682.v1
https://doi.org/10.1158/1078-0432.c.6523682.v1
Autor:
Anil K. Sood, Keith A. Baggerly, Wei Hu, Cristina Ivan, Bulent Ozpolat, Gabriel Lopez-Berestein, Rajesha Rupaimoole, Sherry Y. Wu, Heather J. Dalton, Jamie Guenthoer, Robert L. Coleman, Erin K. Crane, Alpa M. Nick, Anna K. Unruh, Shelley M. Herbrich, Kshipra Gharpure, Susan L. Tucker
PDF file - 2766KB, Supplementary methods and reports describing all data analyses. Supplementary Table 1. Probesets (N=47) and associated genes (N=38) having consistent differences in expression between residual disease (RD) and No-RD patients in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47a49e1975bfd9ffd55f06a963712a72
https://doi.org/10.1158/1078-0432.22457747.v1
https://doi.org/10.1158/1078-0432.22457747.v1