Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Shelley L. Moores"'
Autor:
Andrew V. Stachulski, Chandrakala Pidathala, Eleanor C. Row, Raman Sharma, Neil G. Berry, Alexandre S. Lawrenson, Shelley L. Moores, Mazhar Iqbal, Joanne Bentley, Sarah A. Allman, Geoffrey Edwards, Alison Helm, Jennifer Hellier, Brent E. Korba, J. Edward Semple, Jean-Francois Rossignol
Publikováno v:
Journal of Medicinal Chemistry. 54:8670-8680
We report the activities of a number of thiazolides [2-hydroxyaroyl-N-(thiazol-2-yl)amides] against hepatitis C virus (HCV) genotypes IA and IB, using replicon assays. The structure-activity relationships (SARs) of thiazolides against HCV are less pr
Autor:
Neil G. Berry, Shelley L. Moores, Eleanor C. Row, Andrew V. Stachulski, I.S. Adagu, A. C. Lilian Low, David C. Warhurst, Jean-Francois Rossignol
Publikováno v:
Journal of Medicinal Chemistry. 49:1450-1454
We report the preparation and antiparasitic activity in vitro and in vivo of a series of isoflavone derivatives related to genistein. These analogues retain the 5,7-dihydroxyisoflavone core of genistein: direct genistein analogues (2-H isoflavones),
Publikováno v:
International journal for parasitology. 37(10)
Neospora caninum represents an important pathogen causing stillbirth and abortion in cattle and neuromuscular disease in dogs. Nitazoxanide (NTZ) and its deacetylated metabolite tizoxanide (TIZ) are nitro-thiazolyl-salicylamide drugs with a broad-spe
Autor:
Chandrakala Pidathala, Andrew Hemphill, Rebecca Stettler, Neil G. Berry, Andrew V. Stachulski, Shelley L. Moores, Marco Esposito, Jean-Francois Rossignol, Norbert Müller
Publikováno v:
Antimicrobial agents and chemotherapy. 49(9)
The thiazolide nitazoxanide [2-acetolyloxy- N -(5-nitro-2-thiazolyl)benzamide] (NTZ) exhibits a broad spectrum of activities against a wide variety of intestinal and tissue-dwelling helminths, protozoa, and enteric bacteria infecting animals and huma
Autor:
Andrew V. Stachulski, Chandrakala Pidathala, EleanorC. Row, Raman Sharma, Neil G. Berry, Alexandre S. Lawrenson, Shelley L. Moores, Mazhar Iqbal, Joanne Bentley, SarahA. Allman, Geoffrey Edwards, Alison Helm, Jennifer Hellier, Brent E. Korba, J. Edward Semple, Jean-Francois Rossignol
Publikováno v:
Journal of Medicinal Chemistry; Dec2011, Vol. 54 Issue 24, p8670-8680, 11p