Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Shelley J Allen"'
Autor:
David C. Emery, Maria Davies, Tanya L. Cerajewska, Jelena Taylor, Mae Hazell, Alex Paterson, Shelley J. Allen-Birt, Nicola X. West
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
IntroductionAlzheimer’s (AD) and Parkinson’s disease (PD) are neurodegenerative conditions characterized by incremental deposition of β-amyloid (Aβ) and α-synuclein in AD and PD brain, respectively, in relatively conserved patterns. Both are a
Externí odkaz:
https://doaj.org/article/a7cd303dce9c44d7a90d409cec47a004
Autor:
David C. Emery, Tanya L. Cerajewska, Joon Seong, Maria Davies, Alex Paterson, Shelley J. Allen-Birt, Nicola X. West
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2021)
The use of Next Generation Sequencing (NGS) techniques has generated a wide variety of blood microbiome data. Due to the large variation in bacterial DNA profiles between studies and the likely high concentrations of cell-free bacterial DNA in the bl
Externí odkaz:
https://doaj.org/article/cd36da9fdd564fbf89183bc9ef81423f
Autor:
Rachel M. Barker, Jeff M. P. Holly, Kalina M. Biernacka, Shelley J. Allen-Birt, Claire M. Perks
Publikováno v:
Frontiers in Endocrinology, Vol 11 (2020)
This minireview is a brief overview examining the roles of insulin-like growth factors (IGFs) and the PI3K/Akt pathway in two apparently unconnected diseases: Alzheimer's dementia and cancer. For both, increased age is a major risk factor, and, in ac
Externí odkaz:
https://doaj.org/article/7a34194ef26b4c369f6d2b778a079135
Autor:
David C. Emery, Deborah K. Shoemark, Tom E. Batstone, Christy M. Waterfall, Jane A. Coghill, Tanya L. Cerajewska, Maria Davies, Nicola X. West, Shelley J. Allen
Publikováno v:
Frontiers in Aging Neuroscience, Vol 9 (2017)
The neurological deterioration associated with Alzheimer’s disease (AD), involving accumulation of amyloid-beta peptides and neurofibrillary tangles, is associated with evident neuroinflammation. This is now seen to be a significant contributor to
Externí odkaz:
https://doaj.org/article/3d2a064b980d4b818b14715f27d86fad
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39fffeee32a6341f9e03dc6e3b5529dd
https://doi.org/10.1016/j.jalz.2018.06.899
https://doi.org/10.1016/j.jalz.2018.06.899
Publikováno v:
Harris, R, Miners, J S, Allen, S & Love, S 2018, ' VEGFR1 and VEGFR2 in Alzheimer's Disease ', Journal of Alzheimer's Disease, vol. 61, no. 2, pp. 741-752 . https://doi.org/10.3233/JAD-170745
Vascular endothelial growth factor (VEGF) is a potent angiogenic factor. Despite upregulation of VEGF in the brain in Alzheimer's disease (AD), probably in response to amyloid-β, vasoconstriction, and tissue hypoxia, there is no consequent increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be0864538d37e047b91d033059479588
https://hdl.handle.net/1983/54bdac0a-b619-4e86-9ab3-012ccf6fae05
https://hdl.handle.net/1983/54bdac0a-b619-4e86-9ab3-012ccf6fae05
Publikováno v:
Gerardo-Aviles, J, Allen-Birt, S & Kehoe, P 2017, Renin-angiotensin system microRNAs : special focus on the brain . in Renin-angiotensin system : past, present and future . Croatia . https://doi.org/10.5772/67080
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression with important roles in cancer, cardiovascular and neurological disorders. Present in the brain, they play numerous regulatory roles shaping the proteome in an orchestrated man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92c73905f049e6d30e6a525b3d8c8816
https://hdl.handle.net/1983/da230ba7-c887-4deb-a49f-c1073e073b63
https://hdl.handle.net/1983/da230ba7-c887-4deb-a49f-c1073e073b63
Autor:
Christy Waterfall, Maria Davies, Shelley J Allen, Deborah K. Shoemark, Nicola X West, Tanya L Cerajewska, David C. Emery, Thomas E Batstone, Jane A. Coghill
Publikováno v:
Emery, D, Shoemark, D, Batstone, T, Waterfall, C, Coghill, J, Cerajewska, T, Davies, M, West, N & Allen-Birt, S 2017, ' 16S rRNA next generation sequencing analysis shows bacteria in Alzheimer’s post-mortem brain ', Frontiers in Aging Neuroscience, vol. 9, 195 . https://doi.org/10.3389/fnagi.2017.00195
Frontiers in Aging Neuroscience, Vol 9 (2017)
Frontiers in Aging Neuroscience
Frontiers in Aging Neuroscience, Vol 9 (2017)
Frontiers in Aging Neuroscience
The neurological deterioration associated with Alzheimer’s disease (AD), involving accumulation of amyloid-beta peptides and neurofibrillary tangles, is associated with evident neuroinflammation. This is now seen to be a significant contributor to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fa9c00e9a33ab30a24f0843e039bdbc
https://research-information.bris.ac.uk/en/publications/c4a9e319-cf53-41f1-a2df-4f0cfe1cd739
https://research-information.bris.ac.uk/en/publications/c4a9e319-cf53-41f1-a2df-4f0cfe1cd739
Autor:
Shelley J. Allen
We now know that the onset of the pathological processes leading to Alzheimer’s disease (AD) may be 15–20 years before symptoms appear. This focuses attention on synaptic changes and the early role of tau, and less on the hallmark amyloid plaques
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3a066150cf3fc45f9c066923b993475e
https://doi.org/10.1093/med/9780198779803.003.0002
https://doi.org/10.1093/med/9780198779803.003.0002
Autor:
Shelley J. Allen-Birt
Publikováno v:
Oxford Medicine Online ISBN: 9780198779803
Providing clinicians with the latest developments in research, this new edition of Alzheimer's Disease is a succinct and practical introduction to the diagnosis, evaluation, and management of Alzheimer’s disease. Part of the Oxford Neuropsychiatry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5062092d62df7040b32d370eee376df9
https://doi.org/10.1093/med/9780198779803.001.0001
https://doi.org/10.1093/med/9780198779803.001.0001