Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Shelley F Stone"'
Autor:
Stephen P J Macdonald, Shelley F Stone, Claire L Neil, Pauline E van Eeden, Daniel M Fatovich, Glenn Arendts, Simon G A Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110678 (2014)
To identify biomarkers which distinguish severe sepsis/septic shock from uncomplicated sepsis in the Emergency Department (ED).Patients with sepsis underwent serial blood sampling, including arrival in the ED and up to three subsequent time points ov
Externí odkaz:
https://doaj.org/article/f0a67426bc2c49529a4e3927be22b38c
Autor:
Shelley F Stone, Anthony Bosco, Anya Jones, Claire L Cotterell, Pauline E van Eeden, Glenn Arendts, Daniel M Fatovich, Simon G A Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101409 (2014)
BACKGROUND: Systemic spread of immune activation and mediator release is required for the development of anaphylaxis in humans. We hypothesized that peripheral blood leukocyte (PBL) activation plays a key role. OBJECTIVE: To characterize PBL genomic
Externí odkaz:
https://doaj.org/article/fa1f3451390d4506a200e25dbfe9e5cf
Autor:
Shelley F Stone, Geoffrey K Isbister, Seyed Shahmy, Fahim Mohamed, Chandana Abeysinghe, Harendra Karunathilake, Ariaranee Ariaratnam, Tamara E Jacoby-Alner, Claire L Cotterell, Simon G A Brown
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 7, Iss 7, p e2326 (2013)
BACKGROUND: Snake bite is one of the most neglected public health issues in poor rural communities worldwide. In addition to the clinical effects of envenoming, treatment with antivenom frequently causes serious adverse reactions, including hypersens
Externí odkaz:
https://doaj.org/article/38975a96e0e44b29b6343b6c51d860ea
Autor:
Pauline E van Eeden, Michael D Wiese, Susan Aulfrey, Belinda J Hales, Shelley F Stone, Simon G A Brown
Publikováno v:
PLoS ONE, Vol 6, Iss 1, p e16741 (2011)
We adapted DELFIA™ (dissociation-enhanced lanthanide fluoroimmunoassay), a time resolved fluorescence method, to quantitate whole venom specific and allergenic peptide-specific IgE (sIgE), sIgG(1) and sIgG(4) in serum from people clinically allergi
Externí odkaz:
https://doaj.org/article/3780bf22d1ca448c96f882caf82f91d1
Autor:
Shelley F. Stone, Glenn Arendts, Christopher W.L. Armstrong, Simon G A Brown, Graeme J. Hankey, Daniel M Fatovich, Pauline E. van Eeden
Publikováno v:
Journal of Clinical Neuroscience. 23:130-134
We present a young woman (with an identical twin sister) who arrived at the Emergency Department (ED) within 1 hour of her initial stroke symptoms. Previous microarray studies have demonstrated differential expression of multiple genes between stroke
Autor:
Erika Bosio, Stephen P J Macdonald, Daniel M Fatovich, Simon G A Brown, Sally Burrows, Shelley F. Stone, Abbie Francis, Glenn Arendts
Publikováno v:
Journal of innate immunity. 11(1)
Background: We have previously identified the upregulation of the innate immune response, neutrophil activation, and apoptosis during anaphylaxis using a microarray approach. This study aimed to validate the differential gene expression and investiga
Publikováno v:
British Journal of Clinical Pharmacology. 78:1-13
Hypersensitivity reactions including anaphylaxis have been reported for nearly all classes of therapeutic reagents and these reactions can occur within minutes to hours of exposure. These reactions are unpredictable, not directly related to dose or t
Autor:
Glenn Arendts, Simon G A Brown, Sally Burrows, Daniel M Fatovich, Yusuf Nagree, Stephen P J Macdonald, Mani Rajee, Erika Bosio, Hugh Mitenko, Shelley F. Stone, Abbie Francis
Publikováno v:
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 47(3)
Background The mechanisms involved in the amplification of the mast cell response during anaphylaxis are unclear. Mouse models of anaphylaxis demonstrate the critical involvement of neutrophils. These innate immune cells are highly abundant in periph
Autor:
Shelley F. Stone, Pauline E. van Eeden, Simon G A Brown, Glenn Arendts, Ellen MacDonald, Daniel M Fatovich
Publikováno v:
Emergency Medicine Australasia. 24:31-36
Autor:
Niamh M. Keane, Martyn A. French, John R. Warmington, Kate Burgess, Shelley F. Stone, Ian James, Patricia Price, Andrew Y. F. Lim
Publikováno v:
Journal of Clinical Immunology. 26:160-167
Extended assessments of memory T-cell responses in HIV patients who have a satisfactory virological response to combination antiretroviral therapy (CART) have been limited by availability of longitudinal samples and of antigens to which most individu