Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Shelley B. Hooks"'
Autor:
Phillip T. Dean, Shelley B. Hooks
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
Glioblastoma (GBM) is the most common and aggressive form of malignant glioma. The GBM tumor microenvironment (TME) is a complex ecosystem of heterogeneous cells and signaling factors. Glioma associated macrophages and microglia (GAMs) constitute a s
Externí odkaz:
https://doaj.org/article/8eb1453e5a984befa61088f2580666a9
Autor:
Menbere Y. Wendimu, Shelley B. Hooks
Publikováno v:
Cells, Vol 11, Iss 13, p 2091 (2022)
Neuroinflammation is a hallmark of many neurodegenerative diseases (NDs) and plays a fundamental role in mediating the onset and progression of disease. Microglia, which function as first-line immune guardians of the central nervous system (CNS), are
Externí odkaz:
https://doaj.org/article/ec6f58041be04c759b00befd73325abc
Publikováno v:
Neurosignals, Vol 22, Iss 1, Pp 43-51 (2014)
G protein-coupled receptors (GPCRs) and their ligands are critical regulators of neural progenitor differentiation, and GPCR signaling pathways are regulated by regulator of G protein signaling (RGS) proteins. RGS protein expression is dynamically re
Externí odkaz:
https://doaj.org/article/daa1ff9327784396a379907c2579e5dd
Autor:
Phillip Callihan, Mourad W. Ali, Hector Salazar, Nhat Quach, Xian Wu, Steven L. Stice, Shelley B. Hooks
Publikováno v:
ASN Neuro, Vol 6 (2014)
The bioactive lysophospholipids lysophosphatidic acid (LPA) and sphingosine 1-phosphate (S1P) have diverse effects on the developing nervous system and neural progenitors, but the molecular basis for their pleiotropic effects is poorly understood. We
Externí odkaz:
https://doaj.org/article/f8802614f5b446bf91f97c609243b37c
Autor:
Dylan W Maixner, David Christy, Lingwei Kong, Viacheslav Viatchenko-Karpinski, Kristen A Horner, Shelley B Hooks, Han-Rong Weng
Publikováno v:
Molecular pain. 18
Spinal neuroinflammation plays a critical role in the genesis of neuropathic pain. Accumulating data suggest that abscisic acid (ABA), a phytohormone, regulates inflammatory processes in mammals. In this study, we found that reduction of the LANCL2 r
Autor:
Elena Faccenda, Adam J Pawson, Kirk M. Druey, David L. Roman, Mackenzie M. Spicer, Michael Spedding, Rory A. Fisher, Mohammed Alqinyah, Hoa Phan, Benita Sjögren, Christopher G. Sobey, Yalda Zolghadri, Arthur Christopoulos, Shelley B. Hooks, Simon D. Harding, Thiruma V. Arumugam, Laurie P. Sutton, Behirda Karaj, Stephen P.H. Alexander, Jae-Kyung Lee, Christopher R. Bodle, Peter Buneman, Eamonn Kelly, Zili Luo, Jörg Striessnig, Jane F. Armstrong, Jamie A. Davies, Vincent Shaw, Keqiang Xie, Shreoshi Pal Choudhuri, Katherine E. Squires, Luke D. Mascarenhas, Katelin E. Ahlers-Dannen, Harrison J. McNabb, Kyle J. Gerber, Menbere Wendimu, John A. Peters, Anthony P. Davenport, Doriano Fabbro, Somayeh Layeghi-Ghalehsoukhteh, Havish S. Kantheti, Emma L. Veale, Bandana Chakravarti, Thomas M. Wilkie, Carolina Montañez-Miranda, John R. Hepler, Kirill A. Martemyanov, Christopher Southan, John A. Cidlowski, Qian Zhang, Alistair Mathie, Josephine Buo Dagner, Osita W. Ogujiofor
The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on select
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3d71b6cad2f29e8755e256dd641b2af
Autor:
Carolina Montañez-Miranda, Mohammed Alqinyah, Thomas M. Wilkie, Benita Sjögren, David L. Roman, Somayeh Layeghi-Ghalehsoukhteh, Yalda Zolghadri, Osita W. Ogujiofor, John R. Hepler, Behirda Karaj, Shelley B. Hooks, Havish S. Kantheti, Menbere Wendimu, Rory A. Fisher, Jae-Kyung Lee, Katherine E. Squires, Qian Zhang, Bandana Chakravarti, Katelin E. Ahlers-Dannen, Keqiang Xie, Josephine Bou Dagher, Vincent Shaw, Christopher Bodle, Shreoshi Pal Choudhuri, Harrison J. McNabb, Kyle J. Gerber, Kirill A. Martemyanov, Mackenzie M. Spicer, Kirk M. Druey, Luke D. Mascarenhas, Hoa Phan Thi Nhu, Zili Luo, Laurie P. Sutton
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2021
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Autor:
Carolina Montañez-Miranda, Kirill A. Martemyanov, John R. Hepler, Yalda Zolghadri, Katelin E. Ahlers-Dannen, Luke D. Mascarenhas, Rory A. Fisher, Kirk M. Druey, Josephine Bou Dagher, Thomas M. Wilkie, Zili Luo, Behirda Karaj, Havish S. Kantheti, David L. Roman, Christopher Bodle, Shreoshi Pal Choudhuri, Kyle J. Gerber, Hoa Phan Thi Nhu, Jae-Kyung Lee, Menbere Wendimu, Katherine E. Squires, Laurie P. Sutton, Bandana Chakravarti, Shelley B. Hooks, Vincent Shaw, Mohammed Alqinyah, Keqiang Xie, Benita Sjögren, Mackenzie M. Spicer
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2020
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Autor:
Havish S. Kantheti, Christopher R. Bodle, Zili Luo, Vincent Shaw, Laurie P. Sutton, John R. Hepler, Mohammed Alqinyah, Shreoshi Pal Choudhuri, Katelin E. Ahlers-Dannen, Kyle J. Gerber, Hoa Phan Thi Nhu, Thomas M. Wilkie, Yalda Zolghadri, Keqiang Xie, Benita Sjögren, Kirill A. Martemyanov, Katherine E. Squires, Mackenzie M. Spicer, Rory A. Fisher, Behirda Karaj, Luke D. Mascarenhas, Bandana Chakravarti, Shelley B. Hooks, Josephine Bou Dagher, Kirk M. Druey, David L. Roman, Jae-Kyung Lee
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2020
Regulator of G protein Signaling, or RGS, proteins serve an important regulatory role in signaling mediated by G protein-coupled receptors (GPCRs). They all share a common RGS domain that directly interacts with active, GTP-bound Gα subunits of hete
Autor:
Phillip Dean, James A. Wohlschlegel, Silvia N.J. Moreno, Faris Almutairi, Menbere Wendimu, Mohammed Alqinyah, Shima Rayatpisheh, Roseanne Davila-Rivera, Stephen A. Vella, Shelley B. Hooks
Publikováno v:
Cell Signal
Chronic activation of microglia is a driving factor in the progression of neuroinflammatory diseases, and mechanisms that regulate microglial inflammatory signaling are potential targets for novel therapeutics. Regulator of G protein Signaling 10 is