Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Shella Saint Fleur-Lominy"'
Autor:
Shella Saint Fleur-Lominy, Mate Maus, Martin Vaeth, Ingo Lange, Isabelle Zee, David Suh, Cynthia Liu, Xiaojun Wu, Anastasia Tikhonova, Iannis Aifantis, Stefan Feske
Publikováno v:
Cell Reports, Vol 24, Iss 11, Pp 3045-3060.e5 (2018)
Summary: T cell acute lymphoblastic leukemia (T-ALL) is commonly associated with activating mutations in the NOTCH1 pathway. Recent reports have shown a link between NOTCH1 signaling and intracellular Ca2+ homeostasis in T-ALL. Here, we investigate t
Externí odkaz:
https://doaj.org/article/cc0941eed6cc4ed6b5ba925eadff02f2
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
Cell line IC50 values
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e42955567a62723486f8dfda7696ce2
https://doi.org/10.1158/1541-7786.22517911.v1
https://doi.org/10.1158/1541-7786.22517911.v1
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
Supplementary materials and methods and supplementary figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02609ec252e8f6b3c330df28d01077e1
https://doi.org/10.1158/1541-7786.22517914
https://doi.org/10.1158/1541-7786.22517914
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
RNAseq Gene Lists
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7985eb3a5f95dead1cf23e568fefcd43
https://doi.org/10.1158/1541-7786.22517905
https://doi.org/10.1158/1541-7786.22517905
Autor:
William L. Carroll, Nikki A. Evensen, Aristotelis Tsirigos, Xiaotu Ma, Jinghui Zhang, Patrick A. Brown, Mignon L. Loh, Jun J. Yang, Kjeld Schmiegelow, David T. Teachey, Tori J. Fuller, Takaya Moriyama, Harrison L. Kilberg, Hannah Fay, Anita Qualls, Ashfiyah Chowdhury, Shella Saint Fleur-Lominy, Gunjan Sethia, Sonali Narang, Jason Saliba, Joanna Pierro
S1. Schematic diagram of NSD2 isoform indicating domains, the location of amino acid E1099 within the SET domain, and the targets of the shRNAs. S2. NSD2 Overexpression in B-ALL Cell Lines Does Not Impart Clonal Advantage. S3. Overexpression of REIIB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55c2a09c674f1974fe7cb26e6b312bc1
https://doi.org/10.1158/1541-7786.22517917.v1
https://doi.org/10.1158/1541-7786.22517917.v1
Autor:
Elaine Xiang, Jamie Chin, Jonathan Weltz, Aaron Sango, Meredith Akerman, Michael L. Grossbard, Shella Saint Fleur-Lominy
Publikováno v:
Blood. 140:10806-10807
Autor:
Alexander Wang, Frank Cirrone, Francis Andrew De Los Reyes, John Papadopoulos, Shella Saint Fleur-Lominy, Elaine Xiang
Publikováno v:
Leukemialymphoma. 63(6)
The backbone induction therapy for primary central nervous system lymphoma (PCNSL) is high dose methotrexate (HD-MTX) and rituximab, which can be combined with other chemotherapeutic agents. The optimal dose of HD-MTX remains unclear, as doses betwee
Autor:
Tibor Moskovits, Akiko Koide, Judith D. Goldberg, Shella Saint-Fleur Lominy, Bruce Raphael, Catherine Diefenbach, Jessica Caro, Jun Choi, Sara A Thannickal, David Kaminetzky, Maxim Kreditor, Kenneth B. Hymes, Kenneth A. Stapleford, Michael L. Grossbard, Shohei Koide
Publikováno v:
medRxiv
Patients with hematologic malignancies are a high priority for SARS-CoV-2 vaccination, yet the benefit they will derive is uncertain. We investigated the humoral response to vaccination in 53 non-Hodgkin lymphoma (NHL), Hodgkin lymphoma (HL), or CLL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b8b62e9137fb1c6c7bd089c6258f49
https://doi.org/10.1101/2021.06.02.21257804
https://doi.org/10.1101/2021.06.02.21257804
Autor:
Elizabeth A. Raetz, Mignon L. Loh, Stephen P. Hunger, Xiaotu Ma, Sonali Narang, Christopher E. Mason, Nikki A. Evensen, Kylie M. Getz, Aristotelis Tsirigos, Jun H. Choi, Shella Saint Fleur-Lominy, Stephen Kelly, Gunjan Sethia, Cem Meydan, Richard C. Harvey, Jun J. Yang, Teena Bhatla, William L. Carroll, Patrick A. Brown, Cheryl L. Willman
Publikováno v:
Cancer Res
Although B-cell acute lymphoblastic leukemia (B-ALL) is the most common malignancy in children and while highly curable, it remains a leading cause of cancer-related mortality. The outgrowth of tumor subclones carrying mutations in genes responsible
Autor:
Aristotelis Tsirigos, Harrison L. Kilberg, Joanna Pierro, David T. Teachey, Xiaotu Ma, Nikki A. Evensen, Ashfiyah Chowdhury, William L. Carroll, Gunjan Sethia, Jinghui Zhang, Mignon L. Loh, Takaya Moriyama, Sonali Narang, Jason Saliba, Shella Saint Fleur-Lominy, Jun J. Yang, Patrick A. Brown, Tori Fuller, Kjeld Schmiegelow, Anita Qualls, Hannah Fay
Publikováno v:
Mol Cancer Res
The NSD2 p.E1099K (EK) mutation is observed in 10% of acute lymphoblastic leukemia (ALL) samples with enrichment at relapse indicating a role in clonal evolution and drug resistance. To discover mechanisms that mediate clonal expansion, we engineered