Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Sheli R Radoshitzky"'
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245024 (2021)
Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved.
Externí odkaz:
https://doaj.org/article/520cc08e80134a52a681afdaa509a001
Autor:
Sheli R Radoshitzky, Gianluca Pegoraro, Xi Olì Chī, Lián D Ng, Chih-Yuan Chiang, Lucas Jozwick, Jeremiah C Clester, Christopher L Cooper, Duane Courier, David P Langan, Knashka Underwood, Kathleen A Kuehl, Mei G Sun, Yíngyún Caì, Shu Qìng Yú, Robin Burk, Rouzbeh Zamani, Krishna Kota, Jens H Kuhn, Sina Bavari
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005466 (2016)
Little is known about the repertoire of cellular factors involved in the replication of pathogenic alphaviruses. To uncover molecular regulators of alphavirus infection, and to identify candidate drug targets, we performed a high-content imaging-base
Externí odkaz:
https://doaj.org/article/cf948883981c49e0880b98d99eb5977c
Autor:
Shu Qìng Yú, Yíngyún Caì, Cassandra Lyons, Reed F Johnson, Elena Postnikova, Steven Mazur, Joshua C Johnson, Sheli R Radoshitzky, Adam L Bailey, Michael Lauck, Tony L Goldberg, David H O'Connor, Peter B Jahrling, Thomas C Friedrich, Jens H Kuhn
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151313 (2016)
Simian hemorrhagic fever (SHF) is an often lethal disease of Asian macaques. Simian hemorrhagic fever virus (SHFV) is one of at least three distinct simian arteriviruses that can cause SHF, but pathogenesis studies using modern methods have been scar
Externí odkaz:
https://doaj.org/article/65ec20aa068948a492e2bcdec36f51d0
Autor:
Yíngyún Caì, Shu Qìng Yú, Elena N Postnikova, Steven Mazur, John G Bernbaum, Robin Burk, Téngfēi Zhāng, Sheli R Radoshitzky, Marcel A Müller, Ingo Jordan, Laura Bollinger, Lisa E Hensley, Peter B Jahrling, Jens H Kuhn
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112060 (2014)
Middle East respiratory syndrome coronavirus (MERS-CoV) is a recently isolated betacoronavirus identified as the etiologic agent of a frequently fatal disease in Western Asia, Middle East respiratory syndrome. Attempts to identify the natural reservo
Externí odkaz:
https://doaj.org/article/7f52b184f1244d619c5045dcfc1e7e4b
Autor:
Jeffrey R Kugelman, Michael S Lee, Cynthia A Rossi, Sarah E McCarthy, Sheli R Radoshitzky, John M Dye, Lisa E Hensley, Anna Honko, Jens H Kuhn, Peter B Jahrling, Travis K Warren, Chris A Whitehouse, Sina Bavari, Gustavo Palacios
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50316 (2012)
To identify polymorphic sites that could be used as biomarkers of Ebola virus passage history, we repeatedly amplified Ebola virus (Kikwit variant) in vitro and in vivo and performed deep sequencing analysis of the complete genomes of the viral subpo
Externí odkaz:
https://doaj.org/article/0466352d395d41a49030f3e220a3038d
Autor:
I-Chueh Huang, Charles C Bailey, Jessica L Weyer, Sheli R Radoshitzky, Michelle M Becker, Jessica J Chiang, Abraham L Brass, Asim A Ahmed, Xiaoli Chi, Lian Dong, Lindsay E Longobardi, Dutch Boltz, Jens H Kuhn, Stephen J Elledge, Sina Bavari, Mark R Denison, Hyeryun Choe, Michael Farzan
Publikováno v:
PLoS Pathogens, Vol 7, Iss 1, p e1001258 (2011)
Interferon-inducible transmembrane proteins 1, 2, and 3 (IFITM1, 2, and 3) are recently identified viral restriction factors that inhibit infection mediated by the influenza A virus (IAV) hemagglutinin (HA) protein. Here we show that IFITM proteins r
Externí odkaz:
https://doaj.org/article/32c1e55b700c48ae8fdacde354b2f707
Autor:
Sheli R Radoshitzky, Lindsay E Longobardi, Jens H Kuhn, Cary Retterer, Lian Dong, Jeremiah C Clester, Krishna Kota, John Carra, Sina Bavari
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21398 (2011)
Machupo virus (MACV) is a highly pathogenic New World arenavirus that causes hemorrhagic fever in humans. MACV, as well as other pathogenic New World arenaviruses, enter cells after their GP1 attachment glycoprotein binds to their cellular receptor,
Externí odkaz:
https://doaj.org/article/50dbc88b0a534956810954568203dea6
Autor:
Jonathan Abraham, Jo Ann Kwong, César G Albariño, Jiajie G Lu, Sheli R Radoshitzky, Jorge Salazar-Bravo, Michael Farzan, Christina F Spiropoulou, Hyeryun Choe
Publikováno v:
PLoS Pathogens, Vol 5, Iss 4, p e1000358 (2009)
The ability of a New World (NW) clade B arenavirus to enter cells using human transferrin receptor 1 (TfR1) strictly correlates with its ability to cause hemorrhagic fever. Amapari (AMAV) and Tacaribe (TCRV), two nonpathogenic NW clade B arenaviruses
Externí odkaz:
https://doaj.org/article/beb879c296f74e959df4baba2bec631c
Autor:
Jens H. Kuhn, Scott Adkins, Sergey V. Alkhovsky, Tatjana Avšič-Županc, María A. Ayllón, Justin Bahl, Anne Balkema-Buschmann, Matthew J. Ballinger, Martina Bandte, Martin Beer, Nicolas Bejerman, Éric Bergeron, Nadine Biedenkopf, Laurent Bigarré, Carol D. Blair, Kim R. Blasdell, Steven B. Bradfute, Thomas Briese, Paul A. Brown, Rémy Bruggmann, Ursula J. Buchholz, Michael J. Buchmeier, Alexander Bukreyev, Felicity Burt, Carmen Büttner, Charles H. Calisher, Thierry Candresse, Jeremy Carson, Inmaculada Casas, Kartik Chandran, Rémi N. Charrel, Yuya Chiaki, Anya Crane, Mark Crane, Laurent Dacheux, Elena Dal Bó, Juan Carlos de la Torre, Xavier de Lamballerie, William M. de Souza, Rik L. de Swart, Nolwenn M. Dheilly, Nicholas Di Paola, Francesco Di Serio, Ralf G. Dietzgen, Michele Digiaro, J. Felix Drexler, W. Paul Duprex, Ralf Dürrwald, Andrew J. Easton, Toufic Elbeaino, Koray Ergünay, Guozhong Feng, Claudette Feuvrier, Andrew E. Firth, Anthony R. Fooks, Pierre B. H. Formenty, Juliana Freitas-Astúa, Selma Gago-Zachert, María Laura García, Adolfo García-Sastre, Aura R. Garrison, Scott E. Godwin, Jean-Paul J. Gonzalez, Joëlle Goüy de Bellocq, Anthony Griffiths, Martin H. Groschup, Stephan Günther, John Hammond, Jussi Hepojoki, Melanie M. Hierweger, Seiji Hongō, Masayuki Horie, Hidenori Horikawa, Holly R. Hughes, Adam J. Hume, Timothy H. Hyndman, Dàohóng Jiāng, Gilda B. Jonson, Sandra Junglen, Fujio Kadono, David G. Karlin, Boris Klempa, Jonas Klingström, Michel C. Koch, Hideki Kondō, Eugene V. Koonin, Jarmila Krásová, Mart Krupovic, Kenji Kubota, Ivan V. Kuzmin, Lies Laenen, Amy J. Lambert, Jiànróng Lǐ, Jun-Min Li, François Lieffrig, Igor S. Lukashevich, Dongsheng Luo, Piet Maes, Marco Marklewitz, Sergio H. Marshall, Shin-Yi L. Marzano, John W. McCauley, Ali Mirazimi, Peter G. Mohr, Nick J. G. Moody, Yasuaki Morita, Richard N. Morrison, Elke Mühlberger, Rayapati Naidu, Tomohide Natsuaki, José A. Navarro, Yutaro Neriya, Sergey V. Netesov, Gabriele Neumann, Norbert Nowotny, Francisco M. Ochoa-Corona, Gustavo Palacios, Laurane Pallandre, Vicente Pallás, Anna Papa, Sofia Paraskevopoulou, Colin R. Parrish, Alex Pauvolid-Corrêa, Janusz T. Pawęska, Daniel R. Pérez, Florian Pfaff, Richard K. Plemper, Thomas S. Postler, Françoise Pozet, Sheli R. Radoshitzky, Pedro L. Ramos-González, Marius Rehanek, Renato O. Resende, Carina A. Reyes, Víctor Romanowski, Dennis Rubbenstroth, Luisa Rubino, Artemis Rumbou, Jonathan A. Runstadler, Melanie Rupp, Sead Sabanadzovic, Takahide Sasaya, Heike Schmidt-Posthaus, Martin Schwemmle, Torsten Seuberlich, Stephen R. Sharpe, Mang Shi, Manuela Sironi, Sophie Smither, Jin-Won Song, Kirsten M. Spann, Jessica R. Spengler, Mark D. Stenglein, Ayato Takada, Robert B. Tesh, Jana Těšíková, Natalie J. Thornburg, Nicole D. Tischler, Yasuhiro Tomitaka, Keizō Tomonaga, Noël Tordo, Kenta Tsunekawa, Massimo Turina, Ioannis E. Tzanetakis, Anna Maria Vaira, Bernadette van den Hoogen, Bert Vanmechelen, Nikos Vasilakis, Martin Verbeek, Susanne von Bargen, Jiro Wada, Victoria Wahl, Peter J. Walker, Anna E. Whitfield, John V. Williams, Yuri I. Wolf, Junki Yamasaki, Hironobu Yanagisawa, Gongyin Ye, Yong-Zhen Zhang, Arnfinn Lodden Økland
Publikováno v:
Archives of Virology, 167(12), 2857-2906. Springer Vienna
Archives of Virology, 167(12), 2857-2906
Archives of Virology
Archives of Virology, 2022, 167 (12), pp.2857-2906. ⟨10.1007/s00705-022-05546-z⟩
Archives of Virology 167 (2022) 12
Archives of Virology, 167(12), 2857-2906
Archives of Virology
Archives of Virology, 2022, 167 (12), pp.2857-2906. ⟨10.1007/s00705-022-05546-z⟩
Archives of Virology 167 (2022) 12
50 Pág.
In March 2022, following the annual International Committee on Taxonomy of Viruses (ICTV) ratifcation vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by two new families (bunyavir
In March 2022, following the annual International Committee on Taxonomy of Viruses (ICTV) ratifcation vote on newly proposed taxa, the phylum Negarnaviricota was amended and emended. The phylum was expanded by two new families (bunyavir
Autor:
Sheli R. Radoshitzky, Patrick Iversen, Xianghan Lu, Jing Zou, Suzanne J. F. Kaptein, Kelly S. Stuthman, Sean A. Van Tongeren, Jesse Steffens, Ruoyu Gong, Hoa Truong, Annapurna A. Sapre, Huiling Yang, Xiaodong Xie, Jia Jun Chia, Zhijuan J. Song, Stacey M. Leventhal, Josolyn Chan, Alex Shornikov, Xin Zhang, David Cowfer, Helen Yu, Travis Warren, Tomas Cihlar, Danielle P. Porter, Johan Neyts, Pei-Yong Shi, Jay Wells, John P. Bilello, Joy Y. Feng
Publikováno v:
Scientific Reports. 13
Remdesivir (GS-5734; VEKLURY) is a single diastereomer monophosphoramidate prodrug of an adenosine analog (GS-441524). Remdesivir is taken up by target cells and metabolized in multiple steps to form the active nucleoside triphosphate (GS-443902), wh