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pro vyhledávání: '"Sheldon Spector"'
Data on the oral CRTh2 antagonist QAW039 (fevipiprant) in patients with uncontrolled allergic asthma
Autor:
Veit J. Erpenbeck, Todor A. Popov, David Miller, Steven F. Weinstein, Sheldon Spector, Baldur Magnusson, Wande Osuntokun, Paul Goldsmith, Markus Weiss, Jutta Beier
Publikováno v:
Data in Brief, Vol 9, Iss C, Pp 199-205 (2016)
This article contains data on clinical endpoints (Peak Flow Expiratory Rate, fractional exhaled nitric oxide and total IgE serum levels) and plasma pharmacokinetic parameters concerning the use of the oral CRTh2 antagonist QAW039 (fevipiprant) in mil
Externí odkaz:
https://doaj.org/article/1fbdbd306fae4599b5b54cee145b776c
Autor:
Sheldon Spector, M.D *
Publikováno v:
In Clinical and Applied Immunology Reviews 2001 1(3):229-234
Autor:
Abdelkader Rahmaoui, Sheldon Spector, Carsten Bindslev-Jensen, Emel Bülbül Başkan, Sarbjit S. Saini, Mary S. Bradley, Karin Rosén, Oral Alpan, Jean-Jacques Grob, Marcus Maurer, Janice Canvin, Panayiotis Georgiou
Publikováno v:
The Journal of Investigative Dermatology
Saini, S S, Bindslev-Jensen, C, Maurer, M, Grob, J-J, Bülbül Baskan, E, Bradley, M S, Canvin, J, Rahmaoui, A, Georgiou, P, Alpan, O, Spector, S & Rosén, K 2015, ' Efficacy and safety of omalizumab in patients with chronic idiopathic/spontaneous urticaria who remain symptomatic on H1 antihistamines : a randomized, placebo-controlled study ', Journal of Investigative Dermatology, vol. 135, no. 1, pp. 67-75 . https://doi.org/10.1038/jid.2014.306
Saini, S S, Bindslev-Jensen, C, Maurer, M, Grob, J-J, Bülbül Baskan, E, Bradley, M S, Canvin, J, Rahmaoui, A, Georgiou, P, Alpan, O, Spector, S & Rosén, K 2015, ' Efficacy and Safety of Omalizumab in Patients with Chronic Idiopathic/Spontaneous Urticaria who Remain Symptomatic on H1 Antihistamines: A Randomized, Placebo-Controlled Study : Corrigendum ', Journal of Investigative Dermatology, vol. 135, no. 3, pp. 925 . https://doi.org/10.1038/jid.2014.512
Saini, S S, Bindslev-Jensen, C, Maurer, M, Grob, J-J, Bülbül Baskan, E, Bradley, M S, Canvin, J, Rahmaoui, A, Georgiou, P, Alpan, O, Spector, S & Rosén, K 2015, ' Efficacy and safety of omalizumab in patients with chronic idiopathic/spontaneous urticaria who remain symptomatic on H1 antihistamines : a randomized, placebo-controlled study ', Journal of Investigative Dermatology, vol. 135, no. 1, pp. 67-75 . https://doi.org/10.1038/jid.2014.306
Saini, S S, Bindslev-Jensen, C, Maurer, M, Grob, J-J, Bülbül Baskan, E, Bradley, M S, Canvin, J, Rahmaoui, A, Georgiou, P, Alpan, O, Spector, S & Rosén, K 2015, ' Efficacy and Safety of Omalizumab in Patients with Chronic Idiopathic/Spontaneous Urticaria who Remain Symptomatic on H1 Antihistamines: A Randomized, Placebo-Controlled Study : Corrigendum ', Journal of Investigative Dermatology, vol. 135, no. 3, pp. 925 . https://doi.org/10.1038/jid.2014.512
ASTERIA I was a 40-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of subcutaneous omalizumab as add-on therapy for 24 weeks in patients with chronic idiopathic urticaria/spontaneous urticaria (CIU/CSU) wh
Autor:
Veit J. Erpenbeck, Paul Goldsmith, Steven Weinstein, Markus Weiss, Todor A. Popov, Sheldon Spector, Jutta Beier, Wande Osuntokun, Baldur Magnusson, S. David Miller
Publikováno v:
5.1 Airway Pharmacology and Treatment.
Aim: To collect clinical and pharmacokinetic (PK) data for QAW039 (fevipiprant), a novel oral CRTh2 receptor antagonist, for asthma treatment. Methods: We assessed efficacy (change in trough FEV 1 from baseline to day 29), ACQ scores, PK of QAW039 an
Autor:
M.D Sheldon Spector
Publikováno v:
Clinical and Applied Immunology Reviews. 1:229-234
The link between the upper and lower airways in allergic disease has been demonstrated through associations found in epidemiology, pathophysiology and response to therapy. The upper and lower airways are closely linked in function and disease and are
Autor:
Bruce M. Prenner, Steven Machtinger, William Berger, William N. Sokol, Sherwin Gillman, Stanley P. Galant, Michael Welch, William Ziering, Gary Incaudo, Arthur McLean, Lewis J. Kanter, Sheldon Spector, Alan Goldsobel
Publikováno v:
Annals of Allergy, Asthma & Immunology. 81:203-210
Background The number of allergy skin tests required to evaluate patients with respiratory allergy has recently been challenged by the managed care community. Objectives The purpose of this study was to determine which aeroallergens are prevalent in
Autor:
Jay, Portnoy, Jeffrey D, Miller, P Brock, Williams, Ginger L, Chew, J David, Miller, Fares, Zaitoun, Wanda, Phipatanakul, Kevin, Kennedy, Charles, Barnes, Carl, Grimes, Désirée, Larenas-Linnemann, James, Sublett, David, Bernstein, Joann, Blessing-Moore, David, Khan, David, Lang, Richard, Nicklas, John, Oppenheimer, Christopher, Randolph, Diane, Schuller, Sheldon, Spector, Stephen A, Tilles, Dana, Wallace
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 111(6)
Jay Portnoy, MD; Jeffrey D. Miller, MD; P. Brock Williams, PhD; Ginger L. Chew, ScD *; J. David Miller, PhD; Fares Zaitoun, MD; Wanda Phipatanakul, MD, MS; Kevin Kennedy, MPH; Charles Barnes, PhD; Carl Grimes, CIEC; Desiree Larenas-Linnemann, MD; Jam
Autor:
Parameswaran Nair, Vibeke Backer, Sheldon Spector, Tulin Shekar, Davis Gates, Hendrik Nolte, Frederick E. Hargreave, Ian D. Pavord
Publikováno v:
Respiratory medicine. 107(5)
Summary Objective A well-controlled study in patients with allergic asthma was warranted to assess dose-dependency between fractional concentration of exhaled nitric oxide (FeNO) and sputum eosinophils to a combination of an inhaled corticosteroid pl
Autor:
Sheldon Spector, Ricardo Tan
Publikováno v:
Annals of Allergy, Asthma & Immunology. 100:88-89
Autor:
Mark S Dykewicz, Stanley Fineman, Richard Nicklas, Rufus Lee, Joann Blessing-Moore, James T Li, I Leonard Bernstein, William Berger, Sheldon Spector, Diane Schuller
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 81(5 Pt 2)
The algorithm and text annotations in this document are intended to assist clinical decision making about patients who present with symptoms of rhinitis. This document complements the Executive Summary of Joint Task Force Practice Parameters for Diag