Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Sheldon Rowan"'
Autor:
Anupam K. Mondal, Daniel C. Brock, Sheldon Rowan, Zhi-Hong Yang, Krishna Vamsi Rojulpote, Kelsey M. Smith, Sarah G. Francisco, Eloy Bejarano, Milton A. English, Amy Deik, Sarah Jeanfavre, Clary B. Clish, Alan T. Remaley, Allen Taylor, Anand Swaroop
Publikováno v:
iScience, Vol 27, Iss 2, Pp 108979- (2024)
Summary: A high glycemic index (HGI) diet induces hyperglycemia, a risk factor for diseases affecting multiple organ systems. Here, we evaluated tissue-specific adaptations in the liver and retina after feeding HGI diet to mice for 1 or 12 month. In
Externí odkaz:
https://doaj.org/article/b13e6864cc514103b6dadb00ab4c518b
Autor:
Eloy Bejarano, Elizabeth A. Whitcomb, Rebecca L. Pfeiffer, Kristie L. Rose, Maria José Asensio, José Antonio Rodríguez-Navarro, Alejandro Ponce-Mora, Antolín Canto, Inma Almansa, Kevin L. Schey, Bryan W. Jones, Allen Taylor, Sheldon Rowan
Publikováno v:
Redox Biology, Vol 66, Iss , Pp 102869- (2023)
The lens proteome undergoes dramatic composition changes during development and maturation. A defective developmental process leads to congenital cataracts that account for about 30% of cases of childhood blindness. Gene mutations are associated with
Externí odkaz:
https://doaj.org/article/c11db368416d4869b614ebeb6daca586
Publikováno v:
Bone Reports, Vol 14, Iss , Pp 101065- (2021)
Whole bone strength and resistance to fracture are determined by a combination of bone quantity and bone quality – key factors in determining risk for osteoporosis and age-related fractures. Recent preclinical studies have shown that alterations to
Externí odkaz:
https://doaj.org/article/c6cc216833c641e19c6f6e06f6d6f3fe
Autor:
Phuong T. Lam, Stephanie L. Padula, Thanh V. Hoang, Justin E. Poth, Lin Liu, Chun Liang, Adam S. LeFever, Lindsay M. Wallace, Ruth Ashery-Padan, Penny K. Riggs, Jordan E. Shields, Ohad Shaham, Sheldon Rowan, Nadean L. Brown, Tom Glaser, Michael L. Robinson
Publikováno v:
Human Genomics, Vol 13, Iss 1, Pp 1-17 (2019)
Abstract Background Despite a number of different transgenes that can mediate DNA deletion in the developing lens, each has unique features that can make a given transgenic line more or less appropriate for particular studies. The purpose of this wor
Externí odkaz:
https://doaj.org/article/9f6272314a7f4109ad3fa2c419988d59
Autor:
Gemma Aragonès, Sheldon Rowan, Sarah G. Francisco, Elizabeth A. Whitcomb, Wenxin Yang, Giuliana Perini-Villanueva, Casper G. Schalkwijk, Allen Taylor, Eloy Bejarano
Publikováno v:
Cells, Vol 10, Iss 8, p 1852 (2021)
The glyoxalase system is critical for the detoxification of advanced glycation end-products (AGEs). AGEs are toxic compounds resulting from the non-enzymatic modification of biomolecules by sugars or their metabolites through a process called glycati
Externí odkaz:
https://doaj.org/article/4952ec86a10c4e1eb7a448087ba35769
Autor:
Gemma Aragonès, Sheldon Rowan, Sarah G Francisco, Wenxin Yang, Jasper Weinberg, Allen Taylor, Eloy Bejarano
Publikováno v:
Antioxidants, Vol 9, Iss 11, p 1062 (2020)
Hyperglycemia, a defining characteristic of diabetes, combined with oxidative stress, results in the formation of advanced glycation end products (AGEs). AGEs are toxic compounds that have adverse effects on many tissues including the retina and lens
Externí odkaz:
https://doaj.org/article/c35aadbbe6f74defa29ae874154bfa17
Autor:
Raymond M Anchan, Salil A Lachke, Behzad Gerami-Naini, Jennifer Lindsey, Nicholas Ng, Catherine Naber, Michael Nickerson, Resy Cavallesco, Sheldon Rowan, Jennifer L Eaton, Qiongchao Xi, Richard L Maas
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115106 (2014)
Embryonic stem (ES) cells provide a potentially useful in vitro model for the study of in vivo tissue differentiation. We used mouse and human ES cells to investigate whether the lens regulatory genes Pax6 and Six3 could induce lens cell fate in vitr
Externí odkaz:
https://doaj.org/article/0e56d67adf9f403b80914b144a7a171e
Autor:
Sheldon, Rowan R., Marenco, Christopher W., Do, Woo S., Forte, Dominic M., Weiss, Jessica B., Sohn, Vance Y.
Publikováno v:
In Journal of Surgical Education November-December 2020 77(6):e209-e213
Autor:
Sheldon, Rowan, Eckert, Matthew
Publikováno v:
In Surgical Clinics of North America December 2017 97(6):1425-1447
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