Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Sheldon R, Garrison"'
Autor:
Katy Phelan, Luigi Boccuto, Craig M. Powell, Tobias M. Boeckers, Conny van Ravenswaaij-Arts, R. Curtis Rogers, Carlo Sala, Chiara Verpelli, Audrey Thurm, William E. Bennett, Christopher J. Winrow, Sheldon R. Garrison, Roberto Toro, Thomas Bourgeron
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-4 (2022)
Abstract Phelan-McDermid syndrome (PMS) was initially called the 22q13 deletion syndrome based on its etiology as a deletion of the distal long arm of chromosome 22. These included terminal and interstitial deletions, as well as other structural rear
Externí odkaz:
https://doaj.org/article/399efd35b13d49aca4c80ce2e31e1dfa
Autor:
Christine M. Cutillo, Angela Navarrete-Opazo, Ainslie Tisdale, Sheldon R. Garrison, Maharaj Singh
Publikováno v:
Genetics in Medicine
PURPOSE The vast majority of rare diseases (RDs) are complex, disabling, and life-threatening conditions with a genetic origin. RD patients face significant health challenges and limited treatments, yet the extent of their impact within health care i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96d75468db7c9032a5e70a6501dbbc48
http://europepmc.org/articles/PMC8553605
http://europepmc.org/articles/PMC8553605
Autor:
Katherine J Zappia, Sheldon R Garrison, Oleg Palygin, Andy D Weyer, Marie E Barabas, Michael W Lawlor, Alexander Staruschenko, Cheryl L Stucky
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151602 (2016)
Keratinocytes are the first cells that come into direct contact with external tactile stimuli; however, their role in touch transduction in vivo is not clear. The ion channel Transient Receptor Potential Ankyrin 1 (TRPA1) is essential for some mechan
Externí odkaz:
https://doaj.org/article/0222bd77823f49c692ddc43a9403d6c5
Publikováno v:
Neurol Clin Pract
BackgroundThere is an unmet need for reliable biomarkers to predict disease severity, prognosis, and treatment effect in patients with spinal muscular atrophy (SMA). The purpose of this review is to evaluate the clinical utility of blood-based biomar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a50bc3ebe23de564354947d396bb36eb
https://doi.org/10.1212/cpj.0000000000000872
https://doi.org/10.1212/cpj.0000000000000872
Publikováno v:
Journal of Rehabilitation Medicine-Clinical Communications
Objective Total knee arthroplasty is an effective surgical approach used to treat arthritis and knee trauma. Its utilization has grown, as has the accompanying financial impact, resulting in an equal need to advance physical therapy practice. One eme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8ee5bcfe18ce73f1c3cc139300b067b
https://pubmed.ncbi.nlm.nih.gov/33884118
https://pubmed.ncbi.nlm.nih.gov/33884118
Publikováno v:
Pain. 155:2476-2485
Sickle cell disease (SCD) is associated with acute vaso-occlusive crises that trigger painful episodes and frequently involves ongoing, chronic pain. In addition, both humans and mice with SCD experience heightened cold sensitivity. However, studies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f55a5cac3c3687711e1903abe21fcd31
https://doi.org/10.1016/j.pain.2014.05.030
https://doi.org/10.1016/j.pain.2014.05.030
Autor:
Sheldon R. Garrison, Cheryl L. Stucky
Publikováno v:
Arthritis & Rheumatology. 66:2380-2390
Objective To investigate age-related differences in mechanical sensitivity to inflammatory pain and determine the contribution of transient receptor potential ankyrin 1 (TRPA1) to mechanical hypersensitivity during chronic inflammation in young and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4aa30f3fe139ac4971510dc5dafb3e5c
https://doi.org/10.1002/art.38724
https://doi.org/10.1002/art.38724
Publikováno v:
Pain. 155:896-905
Therapeutic use of general sodium channel blockers, such as lidocaine, can substantially reduce the enhanced activity in sensory neurons that accompanies chronic pain after nerve or tissue injury. However, because these general blockers have signific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68584d44c40f464acc72e6870cd6b469
https://doi.org/10.1016/j.pain.2014.01.012
https://doi.org/10.1016/j.pain.2014.01.012
Autor:
Sheldon R. Garrison, Madhavi Latha Yadav Bangaru, Andrew S. Koopmeiners, Quinn H. Hogan, Daniel Vilceanu, Marko Ljubkovic, Cheryl L. Stucky, Marcel Rigaud, Samantha Mueller, Geza Gemes, Damir Sapunar, Philipp Lirk
Publikováno v:
The Journal of Physiology. 591:1111-1131
The T-junction of sensory neurons in the dorsal root ganglion (DRG) is a potential impediment to action potential (AP) propagation towards the CNS. Using intracellular recordings from rat DRG neuronal somata during stimulation of the dorsal root, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ece4ea9d649e9656bf19b20c8177b8
https://doi.org/10.1113/jphysiol.2012.242750
https://doi.org/10.1113/jphysiol.2012.242750
Publikováno v:
Journal of Neurophysiology. 107:913-922
The cellular proteins that underlie mechanosensation remain largely enigmatic in mammalian systems. Mechanically sensitive ion channels are thought to distinguish pressure, stretch, and other types of tactile signals in skin. Transient receptor poten
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f8de2b3b5dc725da987b30612ee2a97
https://doi.org/10.1152/jn.00658.2011
https://doi.org/10.1152/jn.00658.2011