Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Shelby M King"'
Autor:
Yasar Torres-Yaghi, Nobutaka Hattori, Olivier Rascol, Yu Nakajima, Shelby M. King, Akihisa Mori, Fernando Pagan
Publikováno v:
Clinical Parkinsonism & Related Disorders, Vol 9, Iss , Pp 100224- (2023)
Background: In patients with Parkinson’s Disease (PD), two distinct motor subtypes, tremor dominant (TD) and postural instability and gait difficulty (PIGD), can be differentiated using Unified Parkinson’s Disease Rating Scale (UPDRS) sub-scores.
Externí odkaz:
https://doaj.org/article/37d194e6dc424dd7a3cce9a6f61c24a4
The Pharmacological Potential of Adenosine A2A Receptor Antagonists for Treating Parkinson’s Disease
Publikováno v:
Molecules, Vol 27, Iss 7, p 2366 (2022)
The adenosine A2A receptor subtype is recognized as a non-dopaminergic pharmacological target for the treatment of neurodegenerative disorders, notably Parkinson’s disease (PD). The selective A2A receptor antagonist istradefylline is approved in th
Externí odkaz:
https://doaj.org/article/5fac48f488994ae48da8a548382e877e
Autor:
Eoghainín Ó hAinmhire, Suzanne M Quartuccio, Whay Cheng, Roshan A Ahmed, Shelby M King, Joanna E Burdette
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89553 (2014)
Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transformin
Externí odkaz:
https://doaj.org/article/f96d07137ceb4af39b4e4d5c53e1082f
Publikováno v:
Molecular Biology of the Cell
The authors show that PI(3,4,5)P3 in recycling endosomes is needed for AP-1B recruitment and AP-1Bdependent sorting to the basolateral membrane. Interestingly, AP-1B expression itself triggers the formation of PI(3,4,5)P3 in this location.
Polar
Polar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::299afb9a6036b238bfcdb68ace43f626
https://doi.org/10.1091/mbc.e09-01-0036
https://doi.org/10.1091/mbc.e09-01-0036
Autor:
Roshan A. Ahmed, Suzanne M. Quartuccio, Joanna E. Burdette, Whay Cheng, Shelby M. King, Eoghainín Ó hAinmhire
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89553 (2014)
PLoS ONE
PLoS ONE
Ovarian cancer is the most lethal gynecological disease affecting women in the US. The Cancer Genome Atlas Network identified p53 mutations in 96% of high-grade serous ovarian carcinomas, demonstrating its critical role. Additionally, the Transformin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::895dd216a65bef350f57da4d5edd93ac
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586866/pdf/?tool=EBI
https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24586866/pdf/?tool=EBI
Publikováno v:
Carcinogenesis. 34(5)
Ovarian cancer is the deadliest gynecological malignancy due to detection of cancer at a late stage when the disease has metastasized. One likely progenitor cell type of ovarian cancer is the ovarian surface epithelium (OSE), which proliferates rapid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ab8f2346845edd70efde57312d30bd
https://pubmed.ncbi.nlm.nih.gov/23299406
https://pubmed.ncbi.nlm.nih.gov/23299406
Autor:
Joanna E. Burdette, Randal C. Jaffe, Asgerally T. Fazleabas, Lucia Y. Wu, Shelby M. King, Tyvette S. Hilliard
Ovarian cancer is the most lethal gynecological malignancy affecting American women. Current hypotheses concerning the etiology of ovarian cancer propose that a reduction in the lifetime number of ovulations decreases ovarian cancer risk. Advanced se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::983ff927a0605aeaacb7a7f321f238d2
https://europepmc.org/articles/PMC3638747/
https://europepmc.org/articles/PMC3638747/
Autor:
Shelby M. King, Joanna E. Burdette
Publikováno v:
BMB reports. 44(7)
Serous ovarian cancer is one of the most lethal gynecological malignancies. Progress on effective diagnostics and therapeutics for this disease are hampered by ambiguity as to the cellular origins of this histotype of ovarian cancer, as well as limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aff8cba0961d6c102115a6ce8e24e440
https://pubmed.ncbi.nlm.nih.gov/21777513
https://pubmed.ncbi.nlm.nih.gov/21777513
Publikováno v:
Journal of Visualized Experiments.
Ovarian cancer is the fifth leading cause of cancer deaths in women and has a 63% mortality rate in the United States(1). The cell type of origin for ovarian cancers is still in question and might be either the ovarian surface epithelium (OSE) or the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26f8433402f2a17425ae04fc5ce18ad4
https://doi.org/10.3791/2804-v
https://doi.org/10.3791/2804-v
Publikováno v:
Nature cell biology. 5(12)
It has long been speculated that intracellular pH is a critical regulator of both invertebrate and vertebrate sperm motility1,2,3, and sodium–hydrogen exchange has been suggested as a mediator of such pHi regulation in various instances4,5. Two sod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c73b4efacf715e29e33bb4611163aaa
https://pubmed.ncbi.nlm.nih.gov/14634667
https://pubmed.ncbi.nlm.nih.gov/14634667