Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Shelby L. Steele"'
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 6, Pp 811-822 (2017)
Clustered regularly interspaced palindromic repeats (CRISPR)/Cas-based adaptive immunity against pathogens in bacteria has been adapted for genome editing and applied in zebrafish (Danio rerio) to generate frameshift mutations in protein-coding genes
Externí odkaz:
https://doaj.org/article/29ce7481a4684be6aac67abb6a355c5f
Autor:
Jaime N Wertman, Nicole Melong, Matthew R Stoyek, Olivia Piccolo, Stewart Langley, Benno Orr, Shelby L Steele, Babak Razaghi, Jason N Berman
Publikováno v:
eLife, Vol 9 (2020)
Dose-limiting toxicities for cisplatin administration, including ototoxicity and nephrotoxicity, impact the clinical utility of this effective chemotherapy agent and lead to lifelong complications, particularly in pediatric cancer survivors. Using a
Externí odkaz:
https://doaj.org/article/e581ec34dd7945d49d654d0b84030aa1
Autor:
Jessica E. MacLean, Jaime N. Wertman, Sergey V. Prykhozhij, Emily Chedrawe, Stewart Langley, Shelby L. Steele, Kevin Ban, Kim Blake, Jason N. Berman
Publikováno v:
Genes; Volume 14; Issue 5; Pages: 1086
CHARGE syndrome typically results from mutations in the gene encoding chromodomain helicase DNA-binding protein 7 (CHD7). CHD7 is involved in regulating neural crest development, which gives rise to tissues of the skull/face and the autonomic nervous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225fa1f3777845e7d2c0388d629e52e6
https://doi.org/10.3390/genes14051086
https://doi.org/10.3390/genes14051086
Autor:
Frank M. Smith, Mary Margaret Brown, Craig Midgen, Kim Blake, Roger P. Croll, Jason N. Berman, Matthew R. Stoyek, Shelby L. Steele, Kellie Cloney, Sergey V. Prykhozhij
Publikováno v:
The FEBS Journal. 285:2125-2140
CHARGE syndrome is linked to autosomal-dominant mutations in the CHD7 gene and results in a number of physiological and structural abnormalities, including heart defects, hearing and vision loss, and gastrointestinal (GI) problems. Of these challenge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e2bcd4b3f02b5afa7c8413d006073d
https://doi.org/10.1111/febs.14473
https://doi.org/10.1111/febs.14473
Autor:
Mads Daugaard, Jessica A. Hill, Nicolas Crapoulet, Simi Chacko, Poul H. Sorensen, Lindsay A. McDonald, Matthew D. Cooper, Stephen M. Lewis, Babak Razaghi, Sergey V. Prykhozhij, Matthew R. Stoyek, Shelby L. Steele, William Lin, Jason N. Berman, Ian C. Scott
Publikováno v:
Developmental Dynamics. 247:289-303
BACKGROUND In this study, we reveal a previously undescribed role of the HACE1 (HECT domain and Ankyrin repeat Containing E3 ubiquitin-protein ligase 1) tumor suppressor protein in normal vertebrate heart development using the zebrafish (Danio rerio)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9625030a4f3c030f38cd54bc1deb6417
https://doi.org/10.1002/dvdy.24600
https://doi.org/10.1002/dvdy.24600
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 6, Pp 811-822 (2017)
Disease Models & Mechanisms
Disease Models & Mechanisms
Clustered regularly interspaced palindromic repeats (CRISPR)/Cas-based adaptive immunity against pathogens in bacteria has been adapted for genome editing and applied in zebrafish (Danio rerio) to generate frameshift mutations in protein-coding genes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4ed2011559edf68e9da854bb4c3a82
http://dmm.biologists.org/content/10/6/811
http://dmm.biologists.org/content/10/6/811
Autor:
Sergey V. Prykhozhij, Shelby L. Steele, Adam Shlien, Chansey J. Veinotte, Charlotte Fuller, Christopher R. McMaster, Johane M Robitaille, Babak Razaghi, David Malkin, Jason N. Berman
Publikováno v:
Nucleic Acids Research
We have optimized point mutation knock-ins into zebrafish genomic sites using clustered regularly interspaced palindromic repeats (CRISPR)/Cas9 reagents and single-stranded oligodeoxynucleotides. The efficiency of knock-ins was assessed by a novel ap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781c808558e6d92428fbebea16547ae8
https://pubmed.ncbi.nlm.nih.gov/29905858
https://pubmed.ncbi.nlm.nih.gov/29905858
Autor:
Jason N. Berman, Amina Zoubeidi, Colin Collins, Shelby L. Steele, Alice Holly, Graham Dellaire, Morgan MacDonald, Nicole Melong
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
The zebrafish has become a popular human tumour xenograft model, particularly for solid tumours including prostate cancer (PCa). To date PCa xenotransplantation studies in zebrafish have not been performed in the presence of testosterone, even when e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f3a43a962c140d388a5b0064d176acf
https://doi.org/10.1038/s41598-017-14413-w
https://doi.org/10.1038/s41598-017-14413-w
Autor:
Babak, Razaghi, Shelby L, Steele, Sergey V, Prykhozhij, Matthew R, Stoyek, Jessica A, Hill, Matthew D, Cooper, Lindsay, McDonald, William, Lin, Mads, Daugaard, Nicolas, Crapoulet, Simi, Chacko, Stephen M, Lewis, Ian C, Scott, Poul H B, Sorensen, Jason N, Berman
Publikováno v:
Developmental dynamics : an official publication of the American Association of Anatomists. 247(2)
In this study, we reveal a previously undescribed role of the HACE1 (HECT domain and Ankyrin repeat Containing E3 ubiquitin-protein ligase 1) tumor suppressor protein in normal vertebrate heart development using the zebrafish (Danio rerio) model. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::23d04ca6ce5d702fd7e4cc1f6b3ef297
https://pubmed.ncbi.nlm.nih.gov/29024245
https://pubmed.ncbi.nlm.nih.gov/29024245
Autor:
Patricia A. Wright, Shelby L. Steele, Ian A. Johnston, James R. Kinghorn, Jorge M.O. Fernandes, Matthew G. Mackenzie, Yuzuru Suzuki
Publikováno v:
Comparative Biochemistry and Physiology Part D: Genomics and Proteomics. 1:35-45
Myogenin (Myog) is a muscle-specific basic helix-loop-helix transcription factor that plays an essential role in the specification and differentiation of myoblasts. The myogenin genes from the tiger pufferfish, Takifugu rubripes, and green-spotted pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5f77b8324e0fe173dae3a36d5fb50f
https://doi.org/10.1016/j.cbd.2005.09.003
https://doi.org/10.1016/j.cbd.2005.09.003