Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Shelby L. Hemker"'
Autor:
John C. Fyfe, Shelby L. Hemker, Alycia Frampton, Karthik Raj, Peter L. Nagy, Kristi J. Gibbon, Urs Giger
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-10 (2018)
Abstract Background Three Komondor dogs in a small family and 3 sporadic cases exhibited a constellation of signs that included juvenile-onset of failure-to-thrive, inappetence, vomiting and/or diarrhea, and weakness. In each we documented dyshematop
Externí odkaz:
https://doaj.org/article/87d4179d3299478a9d866223f83ed94c
Autor:
Katherine Pfister, Andrew J. Bodnar, Yijen L. Wu, Jacqueline Ho, Takuto Chiba, Yao Li, Kai Shaikh, Débora M. Cerqueira, Shelby L. Hemker, Elina Mukherjee, Brandon T. Sanders, Yu Leng Phua, Patrick J. Pagano, Sunder Sims-Lucas
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Damage to the renal microvasculature is a hallmark of renal ischemia-reperfusion injury (IRI)–mediated AKI. The miR-17∼92 miRNA cluster (encoding miR-17, -18a, -19a, -20a, -19b-1, and -92a-1) regulates angiogenesis in multiple setting
Autor:
Ryan McAnally, Rachel King, Brian C. Schutte, Shelby L. Hemker, John C. Fyfe, Katharina M. Freiberger, Vicki N. Meyers-Wallen
Publikováno v:
The Cleft Palate-Craniofacial Journal. 58:230-236
Objective: To investigate the gestational timing of morphologic events in normal canine secondary palate development as a baseline for studies in dog models of isolated cleft palate (CP). Methods: Beagle and beagle/cocker spaniel-hybrid fetal dogs we
Autor:
Michael B. Butterworth, April K. Marrone, Andrew Clugston, Dennis Kostka, Kevin Hong Chen, Yu Leng Phua, Andrew J. Bodnar, Jacqueline Ho, Shelby L. Hemker, Xiaoning Liu
Publikováno v:
American Journal of Physiology-Renal Physiology. 316:F993-F1005
We have previously demonstrated that loss of miR-17~92 in nephron progenitors in a mouse model results in renal hypodysplasia and chronic kidney disease. Clinically, decreased congenital nephron endowment because of renal hypodysplasia is associated
Autor:
Peter L. Nagy, Urs Giger, Kristi J. Gibbon, John C. Fyfe, Shelby L. Hemker, Karthik Raj, Alycia Frampton
Publikováno v:
BMC Veterinary Research, Vol 14, Iss 1, Pp 1-10 (2018)
BMC Veterinary Research
BMC Veterinary Research
Background Three Komondor dogs in a small family and 3 sporadic cases exhibited a constellation of signs that included juvenile-onset of failure-to-thrive, inappetence, vomiting and/or diarrhea, and weakness. In each we documented dyshematopoiesis, i
Autor:
Shelby L. Hemker, Dennis Kostka, Andrew J. Bodnar, Débora M. Cerqueira, Melissa J Anslow, Kasey R Cargill, Andrew Clugston, Jacqueline Ho, Sunder Sims-Lucas
Publikováno v:
FASEB J
Low nephron number results in an increased risk for developing hypertension and chronic kidney disease. Intrauterine growth restriction is associated with a nephron deficit in humans, and is commonly caused by placental insufficiency, which results i
Autor:
Andrew J. Bodnar, Jacqueline Ho, Shelby L. Hemker, Loren D. Walensky, Débora M. Cerqueira, Rachel Freer, Yu Leng Phua, Neil A. Hukriede
Publikováno v:
The FASEB Journal. 31:3540-3554
Low nephron endowment at birth has been associated with an increased risk for developing hypertension and chronic kidney disease. We demonstrated in an earlier study that conditional deletion of the microRNA (miRNA)-processing enzyme Dicer from nephr
Autor:
Corynn N Appolonia, Jacqueline Ho, Sunder Sims-Lucas, Daniella M. Ortiz, Débora M. Cerqueira, Radhika Muzumdar, Zhenwei Gong, Elina Mukherjee, Shelby L. Hemker, Andrew J. Bodnar, Favour O. Oladipupo
Publikováno v:
Am J Physiol Renal Physiol
The incidence of diabetes mellitus has significantly increased among women of childbearing age, and it has been shown that prenatal exposure to maternal diabetes increases the risk of associated congenital anomalies of the kidney. Congenital anomalie
Autor:
Dennis Kostka, Jiao Liu, Shelby L. Hemker, Andrew Clugston, Carlton M. Bates, Kasey R Cargill, Andrew J. Bodnar, Anjana Murali, Sunder Sims-Lucas, Jacqueline Ho, Zubaida Saifudeen, Eric S. Goetzman, Elina Mukherjee, Daniel Bushnell
Publikováno v:
J Am Soc Nephrol
BACKGROUND: Nephron progenitors, the cell population that give rise to the functional unit of the kidney, are metabolically active and self-renew under glycolytic conditions. A switch from glycolysis to mitochondrial respiration drives these cells to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8e8a72c8707b21c003c1efc2cf5ba0c
https://europepmc.org/articles/PMC6622426/
https://europepmc.org/articles/PMC6622426/
Autor:
Yu Leng, Phua, Kevin Hong, Chen, Shelby L, Hemker, April K, Marrone, Andrew J, Bodnar, Xiaoning, Liu, Andrew, Clugston, Dennis, Kostka, Michael B, Butterworth, Jacqueline, Ho
Publikováno v:
Am J Physiol Renal Physiol
We have previously demonstrated that loss of miR-17~92 in nephron progenitors in a mouse model results in renal hypodysplasia and chronic kidney disease. Clinically, decreased congenital nephron endowment because of renal hypodysplasia is associated