Výsledky vyhledávání - "Shelby C. Martin"

Sustained inhibition of deacetylases is required for the antitumor activity of the histone deactylase inhibitors panobinostat and vorinostat in models of colorectal cancer

Autor: Shelby C. Martin, Robert D. Ladner, Stephanie T. Kuwahara, Peter M. Wilson, Anthony B. El-Khoueiry, Heinz-Josef Lenz, Melissa J. LaBonte

Publikováno v: Investigational new drugs. 31(4)

Despite compelling preclinical data in colorectal cancer (CRC), the efficacy of HDACIs has been disappointing in the clinic. The goal of this study was to evaluate the effectiveness of vorinostat and panobinostat in a dose- and exposure-dependent man

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dcaec7a078db25f0d9e79e6f9225792
https://pubmed.ncbi.nlm.nih.gov/23299388

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání