Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Shelby A. Blythe"'
Autor:
Elizabeth Eck, Jonathan Liu, Maryam Kazemzadeh-Atoufi, Sydney Ghoreishi, Shelby A Blythe, Hernan G Garcia
Publikováno v:
eLife, Vol 9 (2020)
Thermodynamic models of gene regulation can predict transcriptional regulation in bacteria, but in eukaryotes, chromatin accessibility and energy expenditure may call for a different framework. Here, we systematically tested the predictive power of m
Externí odkaz:
https://doaj.org/article/49acf740508d4b0bbc748b4b5ed78210
Publikováno v:
eLife, Vol 9 (2020)
Because chromatin determines whether information encoded in DNA is accessible to transcription factors, dynamic chromatin states in development may constrain how gene regulatory networks impart embryonic pattern. To determine the interplay between ch
Externí odkaz:
https://doaj.org/article/68ac1b33544f4e35893a6eb094be0309
Autor:
Marissa. M. Gaskill, Isabella V. Soluri, Annemarie E. Branks, Alan P. Boka, Michael R. Stadler, Katherine Vietor, Hao-Yu S. Huang, Tyler J. Gibson, Mustafa Mir, Shelby A. Blythe, Melissa M. Harrison
/SummaryThe eukaryotic genome is organized to enable the precise regulation of gene expression required for development. This organization is established during early development when the embryo transitions from a fertilized germ cell to the totipote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f3267f26c9efa30151a8e471cae5ccc
https://doi.org/10.1101/2022.11.29.518380
https://doi.org/10.1101/2022.11.29.518380
Publikováno v:
eLife, Vol 6 (2017)
In Drosophila, graded expression of the maternal transcription factor Bicoid (Bcd) provides positional information to activate target genes at different positions along the anterior-posterior axis. We have measured the genome-wide binding profile of
Externí odkaz:
https://doaj.org/article/1367d50710f1482c839f3241eba6cbb2
Establishment and maintenance of heritable chromatin structure during early Drosophila embryogenesis
Autor:
Shelby A Blythe, Eric F Wieschaus
Publikováno v:
eLife, Vol 5 (2016)
During embryogenesis, the initial chromatin state is established during a period of rapid proliferative activity. We have measured with 3-min time resolution how heritable patterns of chromatin structure are initially established and maintained durin
Externí odkaz:
https://doaj.org/article/30fb68e0c80c4e1bb3b4b4894dc6cb10
Autor:
Joseph Q Nguyen, Richard W. Carthew, Shelby A. Blythe, Yong Jae Kwon, Kevin G. Nyberg, Greg J. Beitel
Publikováno v:
Fly. 14:34-48
Genome editing via homology-directed repair (HDR) has made possible precise and deliberate modifications to gene sequences. CRISPR/Cas9-mediated HDR is the simplest means to carry this out. However...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::076e8cb6ebf1097b00e623dd2f15ceb4
https://doi.org/10.1080/19336934.2020.1832416
https://doi.org/10.1080/19336934.2020.1832416
Autor:
Jonathan Liu, Hernan G. Garcia, Sydney Ghoreishi, Shelby A. Blythe, Elizabeth Eck, Maryam Kazemzadeh-Atoufi
Publikováno v:
eLife
eLife, Vol 9 (2020)
eLife, Vol 9 (2020)
Thermodynamic models of gene regulation can predict transcriptional regulation in bacteria, but in eukaryotes, chromatin accessibility and energy expenditure may call for a different framework. Here, we systematically tested the predictive power of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0985360836a25adecd4fb4c71e0ac0c
https://doi.org/10.7554/elife.56429
https://doi.org/10.7554/elife.56429
Autor:
Richard W. Carthew, Yong Jae Kwon, Joseph Q Nguyen, Greg J. Beitel, Shelby A. Blythe, Kevin G. Nyberg
Genome editing via homology-directed repair (HDR) has made possible precise and deliberate modifications to gene sequences. CRISPR/Cas9-mediated HDR is the simplest means to carry this out. However, technical challenges remain to improve efficiency a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53e1ac94ee3bc191dbb0b9801279035d
https://doi.org/10.1101/2020.05.07.080762
https://doi.org/10.1101/2020.05.07.080762