Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Shekhar Kadam"'
Autor:
Suresh R. Giri, Bibhuti Bhoi, Chitrang Trivedi, Akshyaya Rath, Rohan Rathod, Anish Sharma, Ramchandra Ranvir, Shekhar Kadam, Kailash Ingale, Hiren Patel, Abraham Nyska, Mukul R. Jain
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Saroglitazar is a novel PPAR-α/γ agonist with predominant PPAR-α activity. In various preclinical models, saroglitazar has been shown to prevent & reverse symptoms of NASH. In view of these observations, and the fact that NASH
Externí odkaz:
https://doaj.org/article/20294723c6a8452ea710ad36979e2b91
Autor:
Dheerendra Pandey, Rajesh Bahekar, Brijesh Sutariya, Dipam Patel, Ramchandra Ranvir, Vishal Patel, Hiren Patel, Amit Joharapurkar, Samadhan Kshirsagar, Mukul R. Jain, Maulik Patel, Shekhar Kadam
Publikováno v:
Cardiovascular & Hematological Agents in Medicinal Chemistry. 16:35-43
Background Obesity, diabetes and dyslipidemica are the key pathogenic stimulus that enhances progression of Non-Alcoholic Fatty Liver Disease (NAFLD). Coagonist of Glucagon Like- Peptide-1 (GLP-1) Receptor (GLP-1R) and Glucagon Receptor (GCGR) are be
Autor:
Dipam Patel, Hiren M. Patel, Shekhar Kadam, Brijesh Sutariya, Mukul R. Jain, Rajesh Bahekar, Amit Joharapurkar, Vishal Patel, Samadhan Kshirsagar, Dheerendra Pandey, Maulik Patel, Ramchandra Ranvir
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 96:587-596
Nonalcoholic fatty liver disease (NAFLD) is often associated with obesity and type 2 diabetes. Coagonists of glucagon-like peptide-1 receptor (GLP-1R) and glucagon receptor (GCGR) are under clinical investigation for the treatment of obesity and type
Autor:
Upendra Bhatnagar, Mukul R. Jain, G.J. Nataraju, Ramchandra Ranvir, B.V. Ravichandra, Shekhar Kadam, Viren R. Kothule
Publikováno v:
Experimental and Toxicologic Pathology. 68:1-13
A retrospective analysis was undertaken at Zydus Research Centre to understand the incidences of spontaneous lesions in endocrine glands of Wistar rats and beagle dogs. The data from a total of 841 Wistar rats (418 males and 423 females) and 144 beag
Autor:
Jaideep Singh, Poonam Giri, Lakshmikant Gupta, Priyal Trivedi, Prashant Delvadia, Manoranjan Sharma, Abhijit Chatterjee, Nuggehally R. Srinivas, Nirmal Patel, Shekhar Kadam
Pharmacokinetics of voriconazole, an anti-fungal agent, was determined in collagen-induced arthritic (CIA) and healthy DBA/1J mice. CIA was confirmed in DBA/1J mice by clinical scoring and histological analysis.In vivo oral pharmacokinetic study (3 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c94a2af68dcf6a2dcdd5a33415c2a8a0
Publikováno v:
Ultrasonics Sonochemistry. 23:302-307
The effect of ultrasound pre-treatment on the drying kinetics of brown seaweed Ascophyllum nodosum under hot-air convective drying was investigated. Pretreatments were carried out at ultrasound intensity levels ranging from 7.00 to 75.78 Wcm(-2) for
Publikováno v:
International Journal of Food Science & Technology. 50:24-31
Summary Brown algae are rich sources of bioactive compounds such as polysaccharides, peptides, omega-3 fatty acids, carotenoids, phenolics, vitamins and minerals. Laminarin is low-molecular-weight polysaccharide and bioactive compound present in brow
Autor:
Brijesh Sutariya, Ramchandra Ranvir, Vishal Patel, Hiren M. Patel, Dipam Patel, Maulik Patel, Shekhar Kadam, Dhreerendra Pandey, Amit Joharapurkar, Rajesh Bahekar, Samadhan Kshirsagar, Mukul R. Jain
Publikováno v:
Chemico-biological interactions. 282
Dyslipidemia enhances progression of atherosclerosis. Coagonist of GLP-1 and glucagon are under clinical investigation for the treatment of obesity and diabetes. Earlier, we have observed that coagonist reduced circulating and hepatic lipids, indepen
Autor:
Akshyaya Rath, Hiren Patel, Sib Sankar Roy, Rohan Manubhai. Rathod, Suresh Giri, Bibhuti Bhoi, Ramchandra Ranvir, Shekhar Kadam, Chitrang Trivedi, Eshani Karmakar, Pankaj R. Patel, Walter Wahli, Prabodha Swain, Mukul R. Jain, Nabanita Das
Publikováno v:
Liver international : official journal of the International Association for the Study of the Liver. 38(6)
Background & Aims: Non‐alcoholic fatty liver disease (NAFLD) and non‐alcoholic steatohepatitis (NASH) are common clinico‐pathological conditions that affect millions of patients worldwide. In this study, the efficacy of saroglitazar, a novel PP
Autor:
Manoranjan Sharma, Abhijit Chatterjee, Umar Malik, Dheerendra Pandey, Akshaya Wagh, Shekhar Kadam, Mukul R. Jain, Jogeswar Mohapatra, Anuj Kumar Singh, Gourang B. Shah, Hiren M. Patel
Publikováno v:
International Immunopharmacology. 17:229-236
Emerging evidence suggest that tumor necrosis factor (TNF)-α plays a major role in pathogenesis of auto-immune hepatitis (AIH) induced liver injury. Blockade of TNF-α synthesis or bio-activity protects against experimental AIH. TNF-α converting en