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Akademický článek

EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis.

Autor: Kevin H M Kuo, Shekeb Khan, Margaret L Rand, Hira S Mian, Elena Brnjac, Linda E Sandercock, Indira Akula, Jean-Philippe Julien, Emil F Pai, Alden E Chesney

Publikováno v: PLoS ONE, Vol 11, Iss 3, p e0149830 (2016)

EspP (E. coli secreted serine protease, large plasmid encoded) is an extracellular serine protease produced by enterohemorrhagic E. coli (EHEC) O157:H7, a causative agent of diarrhea-associated Hemolytic Uremic Syndrome (D+HUS). The mechanism by whic

Externí odkaz: https://doaj.org/article/e477ab7f2c2e4941aa3a8ea2ceaae7a4

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Crystal Structure of the Passenger Domain of the Escherichia coli Autotransporter EspP

Autor: Emil F. Pai, Linda E. Sandercock, Nickolay Y. Chirgadze, Shekeb Khan, Hira S. Mian

Publikováno v: Journal of Molecular Biology. 413:985-1000

Autotransporters represent a large superfamily of known and putative virulence factors produced by Gram-negative bacteria. They consist of an N-terminal “passenger domain” responsible for the specific effector functions of the molecule and a C-te

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce6cba71cbf19f5dcca08f372e2bc4d0
https://doi.org/10.1016/j.jmb.2011.09.028

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EspP, an Extracellular Serine Protease from Enterohemorrhagic E. coli, Reduces Coagulation Factor Activities, Reduces Clot Strength, and Promotes Clot Lysis

Autor: Alden Chesney, Shekeb Khan, Kevin H.M. Kuo, Emil F. Pai, Hira S. Mian, Elena Brnjac, Margaret L. Rand, Jean-Philippe Julien, Linda E. Sandercock, Indira Akula

Publikováno v: PLoS ONE
PLoS ONE, Vol 11, Iss 3, p e0149830 (2016)

Background EspP (E. coli secreted serine protease, large plasmid encoded) is an extracellular serine protease produced by enterohemorrhagic E. coli (EHEC) O157:H7, a causative agent of diarrhea-associated Hemolytic Uremic Syndrome (D+HUS). The mechan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b6c6c8d6c4156bfba066d0ea2dc9b68
https://doi.org/10.1371/journal.pone.0149830

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EspP, An Extracellular Serine Protease From Enterohemorrhagic E. Coli, Induces Coagulopathy In Human Whole Blood and Plasma

Autor: Emil F. Pai, Kevin H.M. Kuo, Alden Chesney, Shekeb Khan, Elena Brnjac

Publikováno v: Blood. 116:4416-4416

Abstract 4416 EspP (E. coli secreted serine protease, large plasmid encoded) is an extracellular serine protease produced by enterohemorrhagic E. coli (EHEC) O157:H7. Brunder et al. (Mol Microbiol 1997, 24:767–78) have shown that EspP cleaves, amon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3f86b278e8bf80699d2dd82a62ab7a1e
https://doi.org/10.1182/blood.v116.21.4416.4416

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