Výsledky vyhledávání - "Sheila Worrall"

Immunohistochemical detection of IgM and IgG in lung tissue of dogs with leptospiral pulmonary haemorrhage syndrome (LPHS)

Autor: Sheila Worrall, Thierry Francey, John J. Callanan, Barbara Kohn, Robert Klopfleisch, Simone Schuller, Horst Posthaus, Jarlath E. Nally, Ariane Schweighauser

Publikováno v: Comparative Immunology, Microbiology and Infectious Diseases. 40:47-53

Leptospiral pulmonary haemorrhage syndrome (LPHS) is a severe form of leptospirosis. Pathogenic mechanisms are poorly understood. Lung tissues from 26 dogs with LPHS, 5 dogs with pulmonary haemorrhage due to other causes and 6 healthy lungs were labe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::312f6e93e63617089c8352cccd1997c3
https://doi.org/10.1016/j.cimid.2015.04.002

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Application of quantitative real-time polymerase chain reaction for the diagnosis of toxoplasmosis and enzootic abortion of ewes

Autor: John Fagan, D. J. Sammin, Máire C. McElroy, Stephen W. Maley, Bryan Markey, C. Brady, H. F. Bassett, J. O’Donovan, P.X. Marques, David Buxton, Jarlath E. Nally, Jorge Gutiérrez, A. Proctor, Sheila Worrall

Publikováno v: Journal of Veterinary Diagnostic Investigation. 24:846-854

Toxoplasma gondii and Chlamydophila abortus are the 2 most common infectious causes of ovine abortion worldwide. These obligate intracellular pathogens are associated with severe placentitis leading to abortion or stillbirth in pregnant ewes, and res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::918fd61963bd477dcfd3059b1002f086
https://doi.org/10.1177/1040638712452730

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Interferon-γ expression in trophoblast cells in pregnant ewes challenged with Chlamydophila abortus

Autor: H. F. Bassett, E. J. Williams, Bryan Markey, D. J. Sammin, J. O’Donovan, Jorge Gutiérrez, A. Proctor, C.R. Reid, P.X. Marques, Jarlath E. Nally, Sheila Worrall

Publikováno v: Journal of Reproductive Immunology. 90:214-219

Pregnant ewes were challenged with Chlamydia abortus at 91-98 days of gestation and euthanised at 14, 21 and 28 days post-challenge. IFNγ mRNA labelling appeared to be co-localised with Chlamydial lipopolysaccharide within trophoblast cells in discr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b89d9edb855322e56311655ed825d54c
https://doi.org/10.1016/j.jri.2011.03.011

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The expression of mucin genes and the presence of mucin gene products in the equine endometrium

Autor: Raúl Miranda-CasoLuengo, E. Fitzpatrick, Carolyn A. Cummins, Wim G. Meijer, Karine Rousseau, Eva Maischberger, Colm J. Reid, David J. Thornton, Mary Gallagher, Jane A. Irwin, Sheila Worrall, Stephen D. Carrington, Vivienne Duggan

Publikováno v: Research in veterinary science. 95(1)

In the equine reproductive tract, little is known about mucin gene expression and the role of mucins in barrier function and host-cell interaction. The aims of the study were to identify equine orthologs of mammalian mucin genes using available equin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e838f4b285d28b9c9cb9771e851f1d12
https://pubmed.ncbi.nlm.nih.gov/23583093

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Detection of Toxoplasma gondii antigens reactive with antibodies from serum, amniotic, and allantoic fluids from experimentally infected pregnant ewes

Autor: David Buxton, C. Brady, H. F. Bassett, Stephen W. Maley, Máire C. McElroy, Jarlath E. Nally, P.X. Marques, D. J. Sammin, E. J. Williams, Bryan Markey, Jorge Gutiérrez, Sheila Worrall, J. O’ Donovan, A. Proctor

Publikováno v: Veterinary parasitology. 185(2-4)

Toxoplasma gondii, an intracellular protozoan parasite, is one of the major causes of infectious abortion in sheep. To further understand the pathogenesis of toxoplasmosis, serum, amniotic and allantoic fluids and foetal stomach contents were collect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c862a187d8e7ac6e5896720e0d3e733a
https://pubmed.ncbi.nlm.nih.gov/22088616

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Amniotic and allantoic fluids from experimentally infected sheep contain immunoglobulin specific for Chlamydophila abortus

Autor: Jarlath E. Nally, Jorge Gutiérrez, Bryan Markey, C. Brady, Máire C. McElroy, James O’ Donovan, A. Proctor, Puneet Souda, P.X. Marques, Sheila Worrall, Julian P. Whitelegge, E. J. Williams, Hugh Basset, D. J. Sammin

Publikováno v: Veterinary immunology and immunopathology. 140(1-2)

Chlamydophila abortus, the aetiological agent of enzootic abortion of ewes (EAE), replicates in trophoblast cells leading to their destruction and dissemination of the bacterium to foetal organs. To further understand the pathogenesis of EAE, amnioti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f0c1d57e961f549718d82b7a0937289
https://pubmed.ncbi.nlm.nih.gov/21126774

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Monitoring clinical outcomes, pathological changes and shedding of Chlamydophila abortus following experimental challenge of periparturient ewes utilizing the natural route of infection

Autor: C. Brady, Jarlath E. Nally, D. J. Sammin, H. F. Bassett, E. J. Williams, J. O’Donovan, Jorge Gutiérrez, A. Proctor, Bryan Markey, P.X. Marques, Sheila Worrall, Máire C. McElroy

Publikováno v: Veterinary microbiology. 147(1-2)

Enzootic abortion of ewes (EAE) caused by Chlamydophila abortus is an important disease resulting in significant lamb loss in most sheep producing countries. Ewes are considered to be naturally infected with C. abortus via the oral–nasal route and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd7bdd5ce29d8aebe69ba32d9e69dcb3
https://pubmed.ncbi.nlm.nih.gov/20638204

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Detection and quantification of Toxoplasma gondii in ovine maternal and foetal tissues from experimentally infected pregnant ewes using real-time PCR

Autor: Jorge Gutiérrez, Stephen W. Maley, D. J. Sammin, Bryan Markey, Jarlath E. Nally, E. J. Williams, David Buxton, A. Proctor, C. Brady, H. F. Bassett, J. O’Donovan, Sheila Worrall, Máire C. McElroy, P.X. Marques

Publikováno v: Veterinary parasitology. 172(1-2)

A real-time PCR (rt-PCR) targeting the 529-bp repeat element (RE) of Toxoplasma gondii was used to detect and quantify the parasite burden in maternal and foetal tissues in 18 seronegative ewes infected with 3000 toxoplasma oocysts on day 90 of pregn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a8933707ff18916484be196f665dea7
https://pubmed.ncbi.nlm.nih.gov/20510517

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Identification of Immunologically Relevant Proteins of Chlamydophila abortus Using Sera from Experimentally Infected Pregnant Ewes

Autor: Julian P. Whitelegge, Puneet Souda, Jarlath E. Nally, Jorge Gutiérrez, Sheila Worrall, D. J. Sammin, E. J. Gutierrez, Máire C. McElroy, P.X. Marques, A. Proctor, J. O’Donovan, H. F. Basset, B. E. Markey, C. Brady

Publikováno v: Clinical and Vaccine Immunology. 17:1491-1491

Chlamydophila abortus is an intracellular pathogen and the etiological agent of enzootic abortion of ewes (EAE). C. abortus has a biphasic development cycle; extracellular infectious elementary bodies (EB) attach and penetrate host cells, where they

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a1272e84d047b729147ae004edbb1a1
https://doi.org/10.1128/cvi.00319-10

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