Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Sheila Willatts"'
Autor:
Sheila Willatts, E. M. Spencer
Publikováno v:
Anaesthesia. 49:422-428
Publikováno v:
Anaesthesia. 49:751-754
Summary The incidence of Gram-negative bacteraemia in 100 patients with sepsis syndrome receiving antibiotics, and admitted to the Intensive Therapy Unit, was only 12%. If endotoxin antibody is only effective in bacteraemic patients and these results
Autor:
Richard Beale, Marc Boehme, Karl F. Rothe, Michael Adolph, Donald L. Bredle, Andreas Meier-Hellmann, Sheila Willatts, Helmuth Forst, Konrad Reinhart, Dieter Boehm, Joerg E. Hoffmann
Publikováno v:
Critical Care Medicine. 32:1662-1668
An initial phase II trial to investigate the safety and therapeutic effect of the endotoxin adsorber system EN 500 in septic patients suffering from presumed Gram-negative infection.Open, controlled, prospective, randomized, multiple-center, parallel
Autor:
Charles L. Sprung, Massimo Antonelli, Arnaldo de Mendonça, Rui Moreno, Sheila Willatts, Francis Cantraine, Jean Louis Vincent, Ricardo Matos, L. G. Thijs, Jukka Takala, Hajo A. Bruining
Publikováno v:
Intensive Care Medicine, 25, 686-696. Springer-Verlag
Objective: To evaluate the performance of total maximum sequential organ failure assessment (SOFA) score and a derived measure, delta SOFA (total maximum SOFA score minus admission total SOFA) as a descriptor of multiple organ dysfunction/failure in
Autor:
A. de Mendonça, Hajo A. Bruining, P. M. Suter, R. Moreno, C. K. Reinhart, Jukka Takala, Sheila Willatts, Jean Louis Vincent, L. G. Thijs
Publikováno v:
Intensive Care Medicine. 22:707-710
Autor:
David F. Treacher, Jurgen Eiselstein, Carola Wiegand-Lohnert, Sheila Willatts, Joachim Eckart, Friedrich Grimminger, Lothar Daum, Felix Stockenhuber, Stuart Withington, Joachim Kempeni, Martin Kaul, Dietmar Krausch, Carmen Bouza, Konrad Reinhart
Publikováno v:
Critical Care Medicine. 24:733-742
To investigate the safety, biological effects, and efficacy of the anti-tumor necrosis factor (TNF) antibody fragment, MAK 195F, in a phase II trial in patient with severe sepsis.Prospective, randomized, open label, placebo-controlled, dose-ranging,
Publikováno v:
Critical Care Medicine. 23:1033-1039
Objective : To assess the benefit gained from administration of the antiendotoxic drug, taurolidine, on outcome in critically ill patients with sepsis syndrome. Design : A prospective, randomized, double-blind trial Setting : The general intensive th
Autor:
E. M. Spencer, Sheila Willatts
Publikováno v:
Intensive Care Medicine. 18:415-421
Objective: To compare isoflurane with midazolam for prolonged sedation in ventilated patients.Design: Randomised controlled study.Setting: General intensive care unit in university teaching hospital.Patients: Sixty patients aged 17–80 years who req
Autor:
D. C. E. Speller, Hilary Humphreys, R. J. Winter, A. Pick, Sheila Willatts, Alasdair P. Macgowan
Publikováno v:
Journal of Antimicrobial Chemotherapy. 30:73-87
Nosocomial infection is a major problem in intensive therapy units (ITUs) and a significant cause of mortality. Selective decontamination of the digestive tract (SDD) has been advocated as a means to reduce ITU morbidity and mortality. Ninety-one pat
Autor:
Jay S. Steingrub, Sheila Willatts, Carl Arneson, José A. Lorente, Jill Donaldson, Jan Bakker, Michael S. Silverman, Robert Grover, Steven H. Grossman, Laurent Holzapfel, Jukka Takala, Desmond P. Breen, Antonio Anzueto, A McLuckie, Ángel Juan Gordo López, Michael Brockway, Geraldine Grove
Publikováno v:
Critical care medicine. 32(1)
Objective: To assess the safety and efficacy of the nitric oxide synthase inhibitor 546C88 in patients with septic shock. The predefined primary efficacy objective was survival at day 28. Design: Multiple-center, randomized, two-stage, double-blind,