Zobrazeno 1 - 10
of 94
pro vyhledávání: '"Sheila V. Graham"'
Publikováno v:
Tumour Virus Research, Vol 18, Iss , Pp 200296- (2024)
Connexins are essential for intercellular communication through gap junctions and the maintenance of cellular and tissue homeostasis. Connexin 43 (Cx43) is the most ubiquitously expressed connexin. As well as regulating homeostasis, Cx43 hemichannels
Externí odkaz:
https://doaj.org/article/f1c37dc1e91442fb9097415266069fd6
Autor:
Sheila V. Graham
Publikováno v:
Viruses, Vol 16, Iss 5, p 783 (2024)
Papillomavirus gene regulation is largely post-transcriptional due to overlapping open reading frames and the use of alternative polyadenylation and alternative splicing to produce the full suite of viral mRNAs. These processes are controlled by a wi
Externí odkaz:
https://doaj.org/article/636200dd969e422998e81299f3e63cce
Autor:
Daniel Guerendiain, Raluca Grigorescu, Anna Kirk, Andrew Stevenson, Matthew T. G. Holden, Jiafeng Pan, Kim Kavanagh, Sheila V. Graham, Kate Cuschieri
Publikováno v:
Cancer Medicine, Vol 11, Iss 22, Pp 4193-4203 (2022)
Abstract Background The incidence of anal cancer is increasing globally. Evidence‐based improvement in early detection and management of this morbid cancer is thus required. In other cancers associated with Human Papillomavirus (HPV), viral status
Externí odkaz:
https://doaj.org/article/035f4eebc22e4d84abc1a54e83c6734b
Autor:
Gladys Kaba, Andrew Stevenson, Samuel Asamoah Sakyi, Thomas Okpoti Konney, Ramya Bhatia, Nicholas A. Titiloye, Samuel A. Oppong, Francis Agyemang-Yeboah, Kate Cuschieri, Sheila V. Graham
Publikováno v:
Tumour Virus Research, Vol 15, Iss , Pp 200261- (2023)
Human papillomavirus (HPV) E6 and E7 oncogene expression is essential for cervical carcinogenesis. Evidence exists that E6/E7 variants may have different transforming activities while the risk of HPV-16 variants (A/D) differs by race/ethnicity. We de
Externí odkaz:
https://doaj.org/article/41807f5df2e64931b63c2a49400da9ca
Publikováno v:
EBioMedicine, Vol 91, Iss , Pp 104577- (2023)
Summary: Background: Hyperthermia is a well-accepted cancer therapy. Microwaves provide a very precise, targeted means of hyperthermia and are currently used to treat plantar warts caused by cutaneous-infective human papillomaviruses (HPVs). Other HP
Externí odkaz:
https://doaj.org/article/2ea15e0d8e684674add8d7e3703bddc0
Autor:
Peng Sun, Li Dong, Alasdair I. MacDonald, Shahrzad Akbari, Michael Edward, Malcolm B. Hodgins, Scott R. Johnstone, Sheila V. Graham
Publikováno v:
Viruses, Vol 7, Iss 10, Pp 5243-5256 (2015)
Human papillomavirus type 16 (HPV16) causes a range of cancers including cervical and head and neck cancers. HPV E6 oncoprotein binds the cell polarity regulator hDlg (human homologue of Drosophila Discs Large). Previously we showed in vitro, and now
Externí odkaz:
https://doaj.org/article/6bbe3dad8df74e00b54f025852508abe
Autor:
Natalia Saiz-Ros, Rafal Czapiewski, Ilaria Epifano, Andrew Stevenson, Selene K. Swanson, Charles R. Dixon, Dario B. Zamora, Marion McElwee, Swetha Vijayakrishnan, Christine A. Richardson, Li Dong, David A. Kelly, Lior Pytowski, Martin W. Goldberg, Laurence Florens, Sheila V. Graham, Eric C. Schirmer
Publikováno v:
Cells, Vol 8, Iss 2, p 120 (2019)
The primary envelopment/de-envelopment of Herpes viruses during nuclear exit is poorly understood. In Herpes simplex virus type-1 (HSV-1), proteins pUL31 and pUL34 are critical, while pUS3 and some others contribute; however, efficient membrane fusio
Externí odkaz:
https://doaj.org/article/c41c1533b52c4d7e86870eed76c105f9
Autor:
Sheila V. Graham
Publikováno v:
Viruses, Vol 9, Iss 9, p 245 (2017)
Human papillomaviruses (HPVs) cause diseases ranging from benign warts to invasive cancers. HPVs infect epithelial cells and their replication cycle is tightly linked with the differentiation process of the infected keratinocyte. The normal replicati
Externí odkaz:
https://doaj.org/article/0453b31b07c24a448907e38a9e6eae81
Autor:
Harry Scott, Li Dong, Andrew Stevenson, Alasdair I. MacDonald, Sharmila Srinivasan, Paola Massimi, Lawrence Banks, Patricia E. Martin, Scott R. Johnstone, Sheila V. Graham
Publikováno v:
Journal of Cell Science.
Gap junction channels, composed of connexins, allow direct cell-to-cell communication. Connexin 43 (Cx43) is widely expressed in tissues, including the epidermis. In a previous study of human papillomavirus-positive cervical epithelial tumour cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55d6a3ed5250f90cc03e93e729df23ea
https://doi.org/10.1242/jcs.259984
https://doi.org/10.1242/jcs.259984
Autor:
Andrew Stevenson, Hegel Hernandez-Lopez, Sally Roberts, Megan E Griffiths, Sarah Mole, Arwa Ali A. Faizo, Sheila V. Graham
Publikováno v:
The Journal of General Virology
The infectious life cycle of human papillomaviruses (HPVs) is tightly linked to keratinocyte differentiation. Evidence suggests a sophisticated interplay between host gene regulation and virus replication. Alternative splicing is an essential process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8653973ad416f8ded9bfed21a4f776
http://europepmc.org/articles/PMC7414453
http://europepmc.org/articles/PMC7414453