Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Sheila Rydziel"'
Autor:
Sheila Rydziel, Lisa Stadmeyer, Deena Durant, Ernesto Canalis, Stefano Zanotti, Anna Smerdel-Ramoya
Publikováno v:
Journal of Biological Chemistry. 282:19762-19772
Nephroblastoma overexpressed (Nov), a member of the Cyr 61, connective tissue growth factor, Nov (CCN) family of proteins, is expressed by osteoblasts, but its function in cells of the osteoblastic lineage is not known. We investigated the effects of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::116ba95937741418bfcf78e221fa4df8
https://doi.org/10.1074/jbc.m700212200
https://doi.org/10.1074/jbc.m700212200
Publikováno v:
Bone. 40:619-626
CCAAT enhancer-binding protein (C/EBP) homologous protein (CHOP), is a member of the C/EBP family of nuclear proteins and plays a role in osteoblastic and adipocytic cell differentiation. CHOP is necessary for normal bone formation, but the consequen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556647d85f7c28867450e78b5223a7bd
https://doi.org/10.1016/j.bone.2006.09.028
https://doi.org/10.1016/j.bone.2006.09.028
Publikováno v:
Journal of Biological Chemistry. 279:5397-5404
Collagenase 3 degrades collagen fibrils and is necessary for bone resorption. Cortisol increases collagenase 3 mRNA in osteoblasts by stabilizing collagenase 3 transcripts. To understand mechanisms involved, we used RNA electrophoretic mobility shift
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cfede60e39e295de980b88b84c79df3
https://doi.org/10.1074/jbc.m311984200
https://doi.org/10.1074/jbc.m311984200
Autor:
Sheila Rydziel, Z. Du, Elizabetta Gazzerro, Leah Priest, Ernesto Canalis, R. D. Devlin, Aris N. Economides
Publikováno v:
Bone. 32:111-119
Noggin is a glycoprotein that binds bone morphogenetic proteins (BMPs) selectively and, when added to osteoblasts, it opposes the effects of BMPs. However, the consequences of its continued expression in stromal cells are not known. We investigated t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4338b6df28c1bb55013325cf7386537c
https://doi.org/10.1016/s8756-3282(02)00948-1
https://doi.org/10.1016/s8756-3282(02)00948-1
Publikováno v:
Journal of Cellular Physiology. 182:239-246
During development, bone morphogenetic proteins (BMPs) induce the differentiation of mesenchymal progenitor cells to enter into the osteoblastic lineage, and BMPs enhance osteoblastic function. BMPs and noggin, a specific binding protein that blocks
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::daa63fe4e831301407131b3a755916f6
https://doi.org/10.1002/(sici)1097-4652(200002)182:2<239::aid-jcp13>3.0.co
https://doi.org/10.1002/(sici)1097-4652(200002)182:2<239::aid-jcp13>3.0.co
Publikováno v:
Journal of Cellular Physiology. 184:326-333
Platelet-derived growth factor (PDGF) BB is a mitogen that stimulates bone resorption and increases collagenase 3 transcription in osteoblasts, although the mechanisms involved are as yet unknown. We examined the effect of PDGF BB on collagenase 3 tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32b75a4bc09cdeb8a6e36a87763144e1
https://doi.org/10.1002/1097-4652(200009)184:3<326::aid-jcp6>3.0.co
https://doi.org/10.1002/1097-4652(200009)184:3<326::aid-jcp6>3.0.co
Insulin-Like Growth Factor II Promoter Expression in Cultured Rodent Osteoblasts and Adult Rat Bone*
Publikováno v:
Endocrinology. 139:2287-2292
Insulin-like growth factor (IGF)-II stimulates bone formation by increasing the replication of cells of the osteoblastic lineage and by enhancing the differentiated function of the osteoblast. Although IGF-II is synthesized by skeletal cells, little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c695389c761fc2cf2aab83a5f4bbd34
https://doi.org/10.1210/endo.139.5.5964
https://doi.org/10.1210/endo.139.5.5964
Publikováno v:
Journal of Cellular Biochemistry. 67:176-183
Insulin-like growth factor (IGF) I is an autocrine regulator of bone remodeling which inhibits bone collagen degradation and interstitial collagenase 3 mRNA levels. The mechanism of this inhibitory effect on collagenase 3 expression is not known. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::800c4e3245ecdae6171f0655a3c74590
https://doi.org/10.1002/(sici)1097-4644(19971101)67:2<176::aid-jcb3>3.0.co
https://doi.org/10.1002/(sici)1097-4644(19971101)67:2<176::aid-jcb3>3.0.co
Publikováno v:
Journal of Cellular Physiology. 170:145-152
Transforming growth factor (TGF) β1 is an autocrine regulator of bone cell function. We demonstrated that TGF β1 enhances bone collagen synthesis, but its effects on collagen degradation are not well characterized. We tested the effects of TGF β1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df02c4dbdf7bce21bce5ec3c0a3ddce9
https://doi.org/10.1002/(sici)1097-4652(199702)170:2<145::aid-jcp6>3.0.co
https://doi.org/10.1002/(sici)1097-4652(199702)170:2<145::aid-jcp6>3.0.co
Publikováno v:
Endocrinology. 137:4665-4670
Insulin-like growth factors (IGF)-I and -II are presumed to act as autocrine regulators of bone formation. Recently, we demonstrated that IGF-I and -II inhibit bone collagen degradation and collagenase-3 synthesis in osteoblast cultures. Therefore, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c87f5f7553a90cdccb87aff9f77694d
https://doi.org/10.1210/endo.137.11.8895331
https://doi.org/10.1210/endo.137.11.8895331