Zobrazeno 1 - 10
of 114
pro vyhledávání: '"Sheila Riazi"'
Autor:
Stanley N. Caroff, Christopher B. Roberts, Henry Rosenberg, Joseph R. Tobin, Stacey Watt, Darlene Mashman, Sheila Riazi, Rosalind M. Berkowitz
Publikováno v:
BMC Anesthesiology, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background Intravenous dantrolene is often prescribed for hypermetabolic syndromes other than the approved indication of malignant hyperthermia (MH). To clarify the extent of and indications for dantrolene use in conditions other than MH, we
Externí odkaz:
https://doaj.org/article/bd5522478214462f84e889f394e38c24
Autor:
Yukari Endo, Linda Groom, Alper Celik, Natalia Kraeva, Chang Seok Lee, Sung Yun Jung, Lois Gardner, Marie-Anne Shaw, Susan L. Hamilton, Philip M. Hopkins, Robert T. Dirksen, Sheila Riazi, James J. Dowling
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
The genetic cause(s) of malignant hyperthermia and exertional heat illness are unknown in approximately 30% of cases. To address this barrier, the authors performed genome sequencing on a large cohort of cases, identifying rare variants in ASPH, a ge
Externí odkaz:
https://doaj.org/article/0f7dda93f47146bdbbcd6f5b2e4e2f5d
Autor:
Eshwar R Tammineni, Lourdes Figueroa, Carlo Manno, Disha Varma, Natalia Kraeva, Carlos A Ibarra, Amira Klip, Sheila Riazi, Eduardo Rios
Publikováno v:
eLife, Vol 12 (2023)
Calcium ion movements between cellular stores and the cytosol govern muscle contraction, the most energy-consuming function in mammals, which confers skeletal myofibers a pivotal role in glycemia regulation. Chronic myoplasmic calcium elevation (“c
Externí odkaz:
https://doaj.org/article/5333c0d70b9d492dab05f804a377068f
Autor:
Mohammed Ali Azam, MBBS, PhD, Praloy Chakraborty, MD, Mahmoud M. Bokhari, MBBS, Keith Dadson, PhD, Beibei Du, MD, PhD, Stéphane Massé, MASc, Daoyuan Si, MD, PhD, Ahmed Niri, BEng, Arjun K. Aggarwal, Patrick F.H. Lai, MSc, Sheila Riazi, MD, MSc, Filio Billia, MD, PhD, Kumaraswamy Nanthakumar, MD
Publikováno v:
Heart Rhythm O2, Vol 2, Iss 6, Pp 733-741 (2021)
Background: Doxorubicin (Dox) is a potent chemotherapeutic agent, but its usage is limited by dose-dependent cardiotoxicity. Intracellular calcium dysregulation has been reported to be involved in doxorubicin-induced cardiomyopathy (DICM). The cardio
Externí odkaz:
https://doaj.org/article/520ddf0a2c92488dace35e0269037145
Autor:
Sara Wasef, Isabelle Laksono, Paras Kapoor, David Tang-Wei, David Gold, Aparna Saripella, Sheila Riazi, Sazzadul Islam, Marina Englesakis, Jean Wong, Frances Chung
Publikováno v:
BMC Anesthesiology, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Subjective cognitive decline may represent at-risk persons progressing to mild cognitive impairment (MCI), which can be exacerbated by effects of anesthesia and surgery. The objective of this systematic review is to identify the m
Externí odkaz:
https://doaj.org/article/54ecec10358f44d49615c0d834bfce77
Autor:
Aparna Saripella, Sara Wasef, Mahesh Nagappa, Sheila Riazi, Marina Englesakis, Jean Wong, Frances Chung
Publikováno v:
BMC Anesthesiology, Vol 21, Iss 1, Pp 1-11 (2021)
Abstract Background The elderly population is highly susceptible to develop post-operative complications after major surgeries. It is not clear whether the comprehensive geriatric care models are effective in reducing adverse events. The objective of
Externí odkaz:
https://doaj.org/article/fe1c0f5135f94e4383e70ad8a269124c
Autor:
Hui J. Wang, Chang Seok Lee, Rachel Sue Zhen Yee, Linda Groom, Inbar Friedman, Lyle Babcock, Dimitra K. Georgiou, Jin Hong, Amy D. Hanna, Joseph Recio, Jong Min Choi, Ting Chang, Nadia H. Agha, Jonathan Romero, Poonam Sarkar, Nicol Voermans, M. Waleed Gaber, Sung Yun Jung, Matthew L. Baker, Robia G. Pautler, Robert T. Dirksen, Sheila Riazi, Susan L. Hamilton
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-20 (2020)
Individuals with malignant hyperthermia susceptibility (MHS) suffer from lifethreatening responses to heat. Here the authors demonstrate that adaptive thermogenesis from brown adipose tissue contributes to this heat sensitivity in a preclinical mouse
Externí odkaz:
https://doaj.org/article/1dca01fbb1744c91925d570cd3ada4fa
Publikováno v:
EClinicalMedicine, Vol 25, Iss , Pp 100464- (2020)
Background: A country level exploratory analysis was conducted to assess the impact of timing and type of national health policy/actions undertaken towards COVID-19 mortality and related health outcomes. Methods: Information on COVID-19 policies and
Externí odkaz:
https://doaj.org/article/f3f673f785e343fda8392b8e9dd17190
Autor:
Eshwar R Tammineni, Natalia Kraeva, Lourdes Figueroa, Carlo Manno, Carlos A Ibarra, Amira Klip, Sheila Riazi, Eduardo Rios
Publikováno v:
eLife, Vol 9 (2020)
Most glucose is processed in muscle, for energy or glycogen stores. Malignant Hyperthermia Susceptibility (MHS) exemplifies muscle conditions that increase [Ca2+]cytosol. 42% of MHS patients have hyperglycemia. We show that phosphorylated glycogen ph
Externí odkaz:
https://doaj.org/article/3ca236418179487d915c08daff42b9d2
Autor:
Luuk R. van den Bersselaar, Nens van Alfen, Nick Kruijt, Erik-Jan Kamsteeg, Miguel A. Fernandez-Garcia, Susan Treves, Sheila Riazi, Chu-Ya Yang, Ignacio Malagon, Lucas T. van Eijk, Baziel G.M. van Engelen, Gert-Jan Scheffer, Heinz Jungbluth, Marc M.J. Snoeck, Nicol C. Voermans
Publikováno v:
Journal of Neuromuscular Diseases. :1-14
Background: Variants in RYR1, the gene encoding the ryanodine receptor-1, can give rise to a wide spectrum of neuromuscular conditions. Muscle imaging abnormalities have been demonstrated in isolated cases of patients with a history of RYR1-related m