Výsledky vyhledávání - "Sheila R. Gillespie"

IL-10 Inhibits FcεRI Expression in Mouse Mast Cells

Autor: Gregorio Gomez, Sandra Odom, Juan Rivera, Randall R. DeMartino, Hey Jin Chong, Paria Mirmonsef, L.Andrew Bouton, Daniel P. Bailey, Anita Gharse, Sheila R. Gillespie, John J. Ryan, Krista Fischer-Stenger, Jingfang Zhu, Carlos Ramírez, Christopher P. Shelburne

Publikováno v: The Journal of Immunology. 172:3181-3188

FcεRI expression and function is a central aspect of allergic disease. Using bone marrow-derived mouse mast cell populations, we have previously shown that the Th2 cytokine IL-4 inhibits FcεRI expression and function. In the current study we show t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::96e589f6d21d7b3fd1f8e6250f5227d6
https://doi.org/10.4049/jimmunol.172.5.3181

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Stat5 expression is critical for mast cell development and survival

Publikováno v: Blood. 102:1290-1297

Interleukin-3 (IL-3) and stem cell factor (SCF) are important mast cell growth and differentiation factors. Since both cytokines activate the transcription factor signal transducer and activator of transcription 5 (Stat5), a known regulator of prolif

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39802adcdfe7f278b05604171e96b102
https://doi.org/10.1182/blood-2002-11-3490

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Stat5: an essential regulator of mast cell biology

Autor: Paria Mirmonsef, Hey Jin Chong, Meredith N. Mann, John J. Ryan, Christopher P. Shelburne, Chris S. Lantz, Mohit Kashyap, Carlos Ramírez, L.Andrew Bouton, Roland P. Piekorz, Anita Gharse, Harry V. Wright, Veronica V. Sexl, Daniel P. Bailey, Sheila R. Gillespie, Margaret E. McCoy

Publikováno v: Molecular Immunology. 38:1187-1191

Interleukin-3 (IL-3) and stem cell factor (SCF) are important mast cell growth and differentiation factors. Since both cytokines activate the transcription factor Stat5, a known regulator of proliferation and survival, we investigated the effects of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64208c242d4262396e348bb3dc5832ea
https://doi.org/10.1016/s0161-5890(02)00061-5

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Combined Stimulation with the T Helper Cell Type 2 Cytokines Interleukin (Il)-4 and IL-10 Induces Mouse Mast Cell Apoptosis

Autor: C. Fitzhugh Yeatman, Lawrence Andrew Bouton, Sarah M. Jacobs-Helber, John J. Ryan, Stephen T. Sawyer, Paria Mirmonsef, Christopher P. Shelburne, Henrietta A. Collins, Sheila R. Gillespie

Publikováno v: The Journal of Experimental Medicine

Mast cells are found in connective and mucosal tissues throughout the body. Their activation via immunoglobulin E (IgE)–antigen interactions is promoted by T helper cell type 2 (Th2) cytokines and leads to the sequelae of allergic disease. We now r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b05478bfea7872fbbd0006fe7be08c97
https://doi.org/10.1084/jem.192.8.1093

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Effect of Preexisting Immunity to Salmonella on the Immune Response to Recombinant Salmonella enterica Serovar Typhimurium Expressing a Porphyromonas gingivalis Hemagglutinin

Autor: Latha Pathangey, T A Brown, Sheila R. Gillespie, James J. Kohler

Publikováno v: Infection and Immunity. 68:3116-3120

Recombinant attenuated Salmonella strains have received much attention recently for their potential as antigen delivery systems for mucosal immunization (4, 14, 20). One concern with the use of Salmonella strains as a vaccine carrier expressing heter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c6e8edae757d9490a35c3e468aca19
https://doi.org/10.1128/iai.68.6.3116-3120.2000

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IL-10 inhibits Fc epsilon RI expression in mouse mast cells

Autor: Sheila R, Gillespie, Randall R, DeMartino, Jingfang, Zhu, Hey Jin, Chong, Carlos, Ramirez, Christopher P, Shelburne, L Andrew, Bouton, Daniel P, Bailey, Anita, Gharse, Paria, Mirmonsef, Sandra, Odom, Gregorio, Gomez, Juan, Rivera, Krista, Fischer-Stenger, John J, Ryan

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 172(5)

FcepsilonRI expression and function is a central aspect of allergic disease. Using bone marrow-derived mouse mast cell populations, we have previously shown that the Th2 cytokine IL-4 inhibits FcepsilonRI expression and function. In the current study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c386cb353e1b0a7fb36c925e98a029e0
https://pubmed.ncbi.nlm.nih.gov/14978125

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