Zobrazeno 1 - 10
of 164
pro vyhledávání: '"Sheila M Keating"'
Autor:
Magnus Gisslen, Sheila M Keating, Serena Spudich, Victor Arechiga, Sophie Stephenson, Henrik Zetterberg, Clara Di Germanio, Kaj Blennow, Dietmar Fuchs, Lars Hagberg, Philip J Norris, Julia Peterson, Barbara L Shacklett, Constantin T Yiannoutsos, Richard W Price
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0250987 (2021)
ObjectiveTo characterize the evolution of central nervous system (CNS) inflammation in HIV-1 infection applying a panel of cerebrospinal fluid (CSF) inflammatory biomarkers to grouped subjects representing a broad spectrum of systemic HIV-1 immune su
Externí odkaz:
https://doaj.org/article/2ec0545adb214b17b48bc2f6ac37006b
Autor:
Shannon Kelly, Evan S Jacobs, Mars Stone, Sheila M Keating, Tzong-Hae Lee, Daniel Chafets, John Heitman, Melanie Dimapasoc, Eva Operskalski, Ward Hagar, Elliott Vichinsky, Michael P Busch, Philip J Norris, Brian Custer, Recipient Epidemiology and Donor Evaluation Study (REDS-III)
Publikováno v:
PLoS ONE, Vol 15, Iss 4, p e0218880 (2020)
People with sickle cell disease (SCD) are reported to have low rates of HIV infection, slower progression to AIDS and lower HIV-associated mortality compared to the general population. Mechanisms of potential resistance to HIV in SCD are incompletely
Externí odkaz:
https://doaj.org/article/cf2e5f2095cc40c79070e2ba6fcd672f
Autor:
Daniel I S Rosenbloom, Peter Bacchetti, Mars Stone, Xutao Deng, Ronald J Bosch, Douglas D Richman, Janet D Siliciano, John W Mellors, Steven G Deeks, Roger G Ptak, Rebecca Hoh, Sheila M Keating, Melanie Dimapasoc, Marta Massanella, Jun Lai, Michele D Sobolewski, Deanna A Kulpa, Michael P Busch, Reservoir Assay Validation and Evaluation Network (RAVEN) Study Group
Publikováno v:
PLoS Computational Biology, Vol 15, Iss 4, p e1006849 (2019)
Quantitative viral outgrowth assays (QVOA) use limiting dilutions of CD4+ T cells to measure the size of the latent HIV-1 reservoir, a major obstacle to curing HIV-1. Efforts to reduce the reservoir require assays that can reliably quantify its size
Externí odkaz:
https://doaj.org/article/b5955aac1a054bdaae557617f2bee089
Autor:
Sheila M Keating, Wes Rountree, Eduard Grebe, Andrea L Pappas, Mars Stone, Dylan Hampton, Christopher A Todd, Marek S Poniewierski, Ana Sanchez, Cassandra G Porth, Thomas N Denny, Michael P Busch, EQAPOL Limiting Antigen (LAg) Incidence Assay External Quality Assurance (EQA) Program
Publikováno v:
PLoS ONE, Vol 14, Iss 9, p e0222290 (2019)
Laboratory assays for identifying recent HIV-1 infections are widely used for estimating incidence in cross-sectional population-level surveys in global HIV-1surveillance. Adequate assay and laboratory performance are required to ensure accurate inci
Externí odkaz:
https://doaj.org/article/d55a41e9565d4576b93b4d0c95f00e09
Autor:
Joseph B Sempa, Alex Welte, Michael P Busch, Jake Hall, Dylan Hampton, Shelley N Facente, Sheila M Keating, Kara Marson, Neil Parkin, Christopher D Pilcher, Gary Murphy, Eduard Grebe, Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA)
Publikováno v:
PLoS ONE, Vol 14, Iss 7, p e0220345 (2019)
BackgroundTwo manufacturers, Maxim Biomedical and Sedia Biosciences Corporation, supply CDC-approved versions of the HIV-1 Limiting Antigen Avidity EIA (LAg) for detecting 'recent' HIV infection in cross-sectional incidence estimation. This study ass
Externí odkaz:
https://doaj.org/article/d84c3385c34e4c6ca1a449a372057bd7
Autor:
Nathan W Cummins, Stacey Rizza, Mark R Litzow, Stephane Hua, Guinevere Q Lee, Kevin Einkauf, Tae-Wook Chun, Frank Rhame, Jason V Baker, Michael P Busch, Nicolas Chomont, Patrick G Dean, Rémi Fromentin, Ashley T Haase, Dylan Hampton, Sheila M Keating, Steven M Lada, Tzong-Hae Lee, Sekar Natesampillai, Douglas D Richman, Timothy W Schacker, Stephen Wietgrefe, Xu G Yu, Joseph D Yao, John Zeuli, Mathias Lichterfeld, Andrew D Badley
Publikováno v:
PLoS Medicine, Vol 14, Iss 11, p e1002461 (2017)
BACKGROUND:Notwithstanding 1 documented case of HIV-1 cure following allogeneic stem cell transplantation (allo-SCT), several subsequent cases of allo-SCT in HIV-1 positive individuals have failed to cure HIV-1 infection. The aim of our study was to
Externí odkaz:
https://doaj.org/article/6cb0f7ce4309430794213dddfb5bf122
Autor:
Sheila M Keating, Jennifer L Dodge, Philip J Norris, John Heitman, Stephen J Gange, Audrey L French, Marshall J Glesby, Brian R Edlin, Patricia S Latham, Maria C Villacres, Ruth M Greenblatt, Marion G Peters, Women’s Interagency HIV Study
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0181004 (2017)
Hepatitis C virus infection induces inflammation and while it is believed that HIV co-infection enhances this response, HIV control may reduce inflammation and liver fibrosis in resolved or viremic HCV infection. Measurement of systemic biomarkers in
Externí odkaz:
https://doaj.org/article/09bb6db1c27f444eab88b3eeb836c2e7
Autor:
Katherine E Schlusser, Christopher Pilcher, Esper G Kallas, Breno R Santos, Steven G Deeks, Shelley Facente, Sheila M Keating, Michael P Busch, Gary Murphy, Alex Welte, Thomas Quinn, Susan H Eshleman, Oliver Laeyendecker
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0172283 (2017)
BACKGROUND:Assays have been developed for cross-sectional HIV incidence estimation using plasma samples. Large scale surveillance programs are planned using dried blood spot (DBS) specimens for incidence assessment. However, limited information exist
Externí odkaz:
https://doaj.org/article/c8d8837d099f42939e6108262bf7bd6c
Autor:
Bhavna Hora, Sheila M Keating, Yue Chen, Ana M Sanchez, Ester Sabino, Gillian Hunt, Johanna Ledwaba, John Hackett, Priscilla Swanson, Indira Hewlett, Viswanath Ragupathy, Sai Vikram Vemula, Peibin Zeng, Kok-Keng Tee, Wei Zhen Chow, Hezhao Ji, Paul Sandstrom, Thomas N Denny, Michael P Busch, Feng Gao, REDS-III and EQAPOL programs
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0157340 (2016)
HIV-1 subtypes and drug resistance are routinely tested by many international surveillance groups. However, results from different sites often vary. A systematic comparison of results from multiple sites is needed to determine whether a standardized
Externí odkaz:
https://doaj.org/article/fd61fb7c5f364bf39e8a490d1d34f696
Autor:
Nath Zungsontiporn, Raquel R Tello, Guangxiang Zhang, Brooks I Mitchell, Matthew Budoff, Kalpana J Kallianpur, Beau K Nakamoto, Sheila M Keating, Philip J Norris, Lishomwa C Ndhlovu, Scott A Souza, Cecilia M Shikuma, Dominic C Chow
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149143 (2016)
BACKGROUND:Persistent inflammation and immune activation has been hypothesized to contribute to increased prevalence of subclinical atherosclerosis and cardiovascular disease (CVD) risk in patients with chronic HIV infection. In this study, we examin
Externí odkaz:
https://doaj.org/article/c3589e2f6c3f4ace861f4ecf0437a849