Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Sheila J.M. O'Connor"'
Publikováno v:
Haematologica, Vol 105, Iss 7 (2020)
Central nervous system involvement in multiple myeloma is a rare complication but carries a very poor prognosis. We provide a review of current literature, including presentation, treatment and survival data, and describe our experience in a regional
Externí odkaz:
https://doaj.org/article/5dd3f509ca994e96906a69778cf586f4
Publikováno v:
Haematologica
Central nervous system involvement in multiple myeloma is a rare complication but carries a very poor prognosis. We provide a review of current literature, including presentation, treatment and survival data, and describe our experience in a regional
Publikováno v:
Methods in Molecular Biology ISBN: 9781071606223
Fluorescent in situ hybridization (FISH) techniques can be used to identify a range of chromosome abnormalities that are clinically significant in many cancers. Multicolor FISH can be used to identify multiple targets, which can be simultaneously det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::00115a6bc13754b39245bfbe2437bf4b
https://doi.org/10.1007/978-1-0716-0623-0_3
https://doi.org/10.1007/978-1-0716-0623-0_3
Autor:
Blanca Gonzalez-Farre, Leticia Quintanilla-Martinez, Dennis D. Weisenburger, Guillem Clot, Fina Climent, Sergi Beltran, Renata Woroniecka, Luis Veloza, David Torrents, Elias Campo, Judith A. Ferry, Dolors Costa, Inmaculada Ribera-Cortada, Jan Delabie, Estella Matutes, Andreas Rosenwald, Sílvia Beà, Kai Fu, Steven H. Swerdlow, Blanca Espinet, Daphne de Jong, Xose S. Puente, Sheila J.M. O’Connor, Miriam Prieto, Eric D. Hsi, Itziar Salaverria, Rafael Valdés-Mas, Alba Navarro, Reiner Siebert, Laurence de Leval, Elaine S. Jaffe, Carlos López-Otín, German Ott, David Martín-García, Susanne Bens, Grzegorz Rymkiewicz, Jesús Gutiérrez-Abril
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Mantle cell lymphoma (MCL) is characterized by the t(11;14)(q13;q32) translocation resulting in overexpression of cyclin D1. However, a small subset of cyclin D1− MCL has been recognized, and approximately one-half of them harbor CCND2 translocatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc15c76b6740c91f0cbb8b83c264fd2f
https://europepmc.org/articles/PMC6396173/
https://europepmc.org/articles/PMC6396173/
Autor:
Rosalind J. Hastings, H B Beverloo, Nicola Foot, E. van den Berg, Dolors Costa, Nick Telford, P Talley, Katrina Rack, Claudia Haferlach, Jacqueline Schoumans, K Martin, Zuzana Zemanova, Sheila J.M. O’Connor, Sabine Stioui, Blanca Espinet, S Jeffries
Publikováno v:
Leukemia
Leukemia, 33(8), 1851-1867. Nature Publishing Group
Leukemia, 33(8), 1851-1867. Nature Publishing Group
Data de publicació electrónica: 29-01-2019 Cytogenomic investigations of haematological neoplasms, including chromosome banding analysis, fluorescence in situ hybridisation (FISH) and microarray analyses have become increasingly important in the cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db37998f9c8dbaf5e816f9ffe539917a
http://hdl.handle.net/10230/41730
http://hdl.handle.net/10230/41730
Autor:
Guy Pratt, John A. Snowden, Hannah Hunter, Treen C. M. Morris, David A Cairns, Jim Cavet, Ernest Heartin, Mark T. Drayson, Sheila J.M. O’Connor, Kwee Yong, Gordon Cook, Sally Chown, Jamie Cavenagh, Anna Hockaday, Jenny Bird, Julia Brown, Cathy D. Williams, A John Ashcroft, Christopher Parrish
Publikováno v:
The Lancet Haematology. 3:e340-e351
The Myeloma X trial previously reported improved durability of response (time to disease progression) in patients with relapsed multiple myeloma with salvage autologous stem-cell transplantation (ASCT) compared with oral cyclophosphamide in patients
Autor:
David A Cairns, Treen C. M. Morris, Jenny Bird, John A. Snowden, Kwee Yong, Gordon Cook, Cathy D. Williams, Julia Brown, Marie Fletcher, Jim Cavet, Hanna Hunter, Anna Chalmers, Christopher Parrish, Jamie Cavenagh, A John Ashcroft, Sheila J.M. O’Connor, Mark T. Drayson
Publikováno v:
The Lancet Oncology. 15:874-885
Summary Background Relapsed multiple myeloma has no standard treatment, and the role of autologous stem-cell transplantation (ASCT) has not been fully defined. We aimed to compare high-dose melphalan plus salvage ASCT with cyclophosphamide in patient
Autor:
Reuben Tooze, Paul Evans, Peter Hillmen, Praveen Baskaran, Darren J. Newton, Sheila J.M. O’Connor, Lisa Worrillow, Andy C. Rawstron, Talha Munir, Abraham M. Varghese, Matthew A. Care, Lee Hazelwood
Chronic lymphocytic leukaemia (CLL) is the most common clonal B-cell disorder characterized by clonal diversity, a relapsing and remitting course, and in its aggressive forms remains largely incurable. Current front-line regimes include agents such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ba773712385a98525f7e953ef0a9a37
https://eprints.whiterose.ac.uk/96412/1/TP_53finalsubmitted.pdf
https://eprints.whiterose.ac.uk/96412/1/TP_53finalsubmitted.pdf
Autor:
Paul Evans, Abraham M. Varghese, Marwan Kwok, Paul Moreton, Darren J. Newton, Sheila J.M. O’Connor, Andy C. Rawstron, Peter Hillmen, Chi Doughty
Publikováno v:
Blood. 128(24)
Minimal residual disease (MRD) negativity, defined as
Autor:
Ruth M. de Tute, Stephen J. Richards, James A. L. Fenton, Peter Hillmen, Fiona Bennett, Marwan Kwok, Marieth Plummer, Andy C. Rawstron, Roger G. Owen, Andrew Jack, Sheila J.M. O’Connor
Publikováno v:
New England Journal of Medicine. 359:575-583
A diagnosis of chronic lymphocytic leukemia (CLL) requires a count of over 5000 circulating CLL-phenotype cells per cubic millimeter. Asymptomatic persons with fewer CLL-phenotype cells have monoclonal B-cell lymphocytosis (MBL). The goal of this stu